Depletion of Pleckstrin Homology Domain Leucine-rich Repeat Protein Phosphatases 1 and 2 by Bcr-Abl Promotes Chronic Myelogenous Leukemia Cell Proliferation through Continuous Phosphorylation of Akt Isoforms
Hirano, Isao, Nakamura, Satoki, Yokota, Daisuke, Ono, Takaaki, Shigeno, Kazuyuki, Fujisawa, Shinya, Shinjo, Kaori, Ohnishi, Kazunori
Published in The Journal of biological chemistry (14.08.2009)
Published in The Journal of biological chemistry (14.08.2009)
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Arsenic trioxide therapy in relapsed or refractory Japanese patients with acute promyelocytic leukemia : Updated outcomes of the phase II study and postremission therapies
SHIGENO, Kazuyuki, NAITO, Kensuke, SAHARA, Naohi, KOBAYASHI, Miki, NAKAMURA, Satoki, FUJISAWA, Sinya, SHINJO, Kaori, TAKESHITA, Akihiro, OHNO, Ryuzo, OHNISHI, Kazunori
Published in International journal of hematology (01.10.2005)
Published in International journal of hematology (01.10.2005)
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Two cases of acute promyelocytic leukemia complicated by torsade de pointes during arsenic trioxide therapy
NAITO, Kensuke, KOBAYASHI, Miki, SAHARA, Naohi, SHIGENO, Kazuyuki, NAKAMURA, Satoki, SHINJO, Kaori, TOBITA, Tadasu, TAKESHITA, Akihiro, OHNO, Ryuzo, OHNISHI, Kazunori
Published in International journal of hematology (01.05.2006)
Published in International journal of hematology (01.05.2006)
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Journal Article
HOXA10 expression induced by Abl kinase inhibitors enhanced apoptosis through PI3K pathway in CML cells
Sugimoto, Yuya, Nakamura, Satoki, Okinaka, Keiji, Hirano, Isao, Ono, Takaaki, Shigeno, Kazuyuki, Shinjo, Kaori, Ohnishi, Kazunori
Published in Leukemia research (01.06.2008)
Published in Leukemia research (01.06.2008)
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KIS induces proliferation and the cell cycle progression through the phosphorylation of p27Kip1 in leukemia cells
Nakamura, Satoki, Okinaka, Keiji, Hirano, Isao, Ono, Takaaki, Sugimoto, Yuya, Shigeno, Kazuyuki, Fujisawa, Shinya, Shinjo, Kaori, Ohnishi, Kazunori
Published in Leukemia research (01.09.2008)
Published in Leukemia research (01.09.2008)
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Etodolac induces apoptosis and inhibits cell adhesion to bone marrow stromal cells in human myeloma cells
Nakamura, Satoki, Kobayashi, Miki, Shibata, Kiyoshi, Sahara, Naohi, Shigeno, Kazuyuki, Shinjo, Kaori, Naito, Kensuke, Hayashi, Hideharu, Ohnishi, Kazunori
Published in Leukemia research (01.02.2006)
Published in Leukemia research (01.02.2006)
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Delayed Recovery of Normal Hematopoiesis in Arsenic Trioxide Treatment of Acute Promyelocytic Leukemia: A Comparison to All-trans Retinoic Acid Treatment
SHINJO, Kaori, TAKESHITA, Akihiro, SAHARA, Naohi, KOBAYASHI, Miki, NAKAMURA, Satoki, SHIGENO, Kazuyuki, NAITO, Kensuke, MAEKAWA, Masato, OHNISHI, Kazunori, OHNO, Ryuzo
Published in Internal Medicine (01.08.2005)
Published in Internal Medicine (01.08.2005)
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Two patients with all-trans retinoic acid-resistant acute promyelocytic leukemia treated successfully with gemtuzumab ozogamicin as a single agent
TAKESHITA, Akihiro, SHINJO, Kaori, YADA, Yoshihiro, TESHIMA, Hirofumi, TAKEUCHI, Jin, OHNISHI, Kazunori, OHNO, Ryuzo, NAITO, Kensuke, MATSUI, Hirotaka, SAHARA, Naohi, SHIGENO, Kazuyuki, SUZUMURA, Taeko, HORII, Toshinobu, SHIRAI, Naohito, MAEKAWA, Masato
Published in International journal of hematology (01.12.2005)
Published in International journal of hematology (01.12.2005)
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New Flow Cytometric Method for Detection of Minimally Expressed Multidrug Resistance P‐Glycoprotein on Normal and Acute Leukemia Cells Using Biotinylated MRK16 and Streptavidin‐RED670 Conjugate
Takeshita, Akihiro, Shinjo, Kaori, Ohnishl, Kazunori, Ohno, Ryuzo
Published in Cancer science (01.06.1995)
Published in Cancer science (01.06.1995)
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All-trans Retinoic Acid (ATRA) Differentiates Acute Promyelocytic Leukemia Cells Independently of P-Glycoprotein (P-gp) Related Multidrug Resistance
Takeshita, Akihiro, Shigeno, Kazuyuki, Shinjo, Kaori, Naito, Kensuke, Ohnishi, Kazunori, Hayashi, Hideharu, Tanimoto, Mitsune, Ohno, Ryuzo
Published in Leukemia & lymphoma (2001)
Published in Leukemia & lymphoma (2001)
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Good prognosis of patients with acute promyelocytic leukemia who achieved second complete remission (CR) with a new retinoid, Am80, after relapse from CR induced by all-trans-retinoic acid
Shinjo, K, Takeshita, A, Ohnishi, K, Sakura, T, Miyawaki, S, Hiraoka, A, Takeuchi, M, Tomoyasu, S, Wakita, H, Ata, K, Fukutani, H, Ueda, R, Ohno, R
Published in International journal of hematology (01.12.2000)
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Published in International journal of hematology (01.12.2000)
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Spicamycin and KRN5500 Induce Apoptosis in Myeloid and Lymphoid Cell Lines with Down‐regulation of Bcl‐2 Expression and Modulation of Promyelocytic Leukemia Protein
Zhang, Wen Jie, Ohnishi, Kazunori, Yoshida, Hitoshi, Pan, Ling, Maksumova, Lola, Muratkhodjaev, Farkhad, Luo, Jian Min, Shigeno, Kazuyuki, Fujisawa, Shinya, Naito, Kensuke, Nakamura, Satoki, Shinjo, Kaori, Takeshita, Akihiro, Ohno, Ryuzo
Published in Cancer science (01.06.2000)
Published in Cancer science (01.06.2000)
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CMC‐544 (inotuzumab ozogamicin) shows less effect on multidrug resistant cells: analyses in cell lines and cells from patients with B‐cell chronic lymphocytic leukaemia and lymphoma
Takeshita, Akihiro, Shinjo, Kaori, Yamakage, Nozomi, Ono, Takaaki, Hirano, Isao, Matsui, Hirotaka, Shigeno, Kazuyuki, Nakamura, Satoki, Tobita, Tadasu, Maekawa, Masato, Ohnishi, Kazunori, Sugimoto, Yoshikazu, Kiyoi, Hitoshi, Naoe, Tomoki, Ohno, Ryuzo
Published in British journal of haematology (01.07.2009)
Published in British journal of haematology (01.07.2009)
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Pharmacokinetics of arsenic species in Japanese patients with relapsed or refractory acute promyelocytic leukemia treated with arsenic trioxide
FUJISAWA, Shinya, OHNO, Ryuzo, HASHIMOTO, Hisakuni, KINOSHITA, Kenji, SHIMOYA, Masahito, KAISE, Toshikazu, OHNISHI, Kazunori, SHIGENO, Kazuyuki, SAHARA, Naohi, NAKAMURA, Satoki, NAITO, Kensuke, KOBAYASHI, Miki, SHINJO, Kaori, TAKESHITA, Akihiro, SUZUKI, Yoshinari
Published in Cancer chemotherapy and pharmacology (01.03.2007)
Published in Cancer chemotherapy and pharmacology (01.03.2007)
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Retraction: Depletion of pleckstrin homology domain leucine-rich repeat protein phosphatases 1 and 2 by Bcr-Abl promotes chronic myelogenous leukemia cell proliferation through continuous phosphorylation of Akt isoforms
Hirano, Isao, Nakamura, Satoki, Yokota, Daisuke, Ono, Takaaki, Shigeno, Kazuyuki, Fujisawa, Shinya, Shinjo, Kaori, Ohnishi, Kazunori
Published in The Journal of biological chemistry (14.05.2010)
Published in The Journal of biological chemistry (14.05.2010)
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Journal Article
Depletion of pleckstrin homology domain leucine-rich repeat protein phosphatases 1 and 2 by Bcr-Abl promotes chronic myelogenous leukemia cell proliferation through continuous phosphorylation of Akt isoforms
Hirano, Isao, Nakamura, Satoki, Yokota, Daisuke, Ono, Takaaki, Shigeno, Kazuyuki, Fujisawa, Shinya, Shinjo, Kaori, Ohnishi, Kazunori
Published in The Journal of biological chemistry (14.05.2010)
Published in The Journal of biological chemistry (14.05.2010)
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Journal Article
Prolongation of the QT interval and ventricular tachycardia in patients treated with arsenic trioxide for acute promyelocytic leukemia
Ohnishi, K, Yoshida, H, Shigeno, K, Nakamura, S, Fujisawa, S, Naito, K, Shinjo, K, Fujita, Y, Matsui, H, Takeshita, A, Sugiyama, S, Satoh, H, Terada, H, Ohno, R
Published in Annals of internal medicine (05.12.2000)
Published in Annals of internal medicine (05.12.2000)
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Abstract 5053: Depletion of PHLPP1 and 2 by Bcr-Abl promotes CML cell proliferation
Hirano, Isao, Nakamura, Satoki, Takemura, Tomonari, Yokota, Daisuke, Ono, Taka-aki, Shinjo, Kaori, Shigeno, Kazuyuki, Fujisawa, Shin-ya, Ohnishi, Kazunori
Published in Cancer research (Chicago, Ill.) (15.04.2010)
Published in Cancer research (Chicago, Ill.) (15.04.2010)
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