Structural analysis reveals TLR7 dynamics underlying antagonism
Tojo, Shingo, Zhang, Zhikuan, Matsui, Hiroyuki, Tahara, Masahiro, Ikeguchi, Mitsunori, Kochi, Mami, Kamada, Mami, Shigematsu, Hideki, Tsutsumi, Akihisa, Adachi, Naruhiko, Shibata, Takuma, Yamamoto, Masaki, Kikkawa, Masahide, Senda, Toshiya, Isobe, Yoshiaki, Ohto, Umeharu, Shimizu, Toshiyuki
Published in Nature communications (15.10.2020)
Published in Nature communications (15.10.2020)
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Journal Article
Crystal Structures and Structure–Activity Relationships of Imidazothiazole Derivatives as IDO1 Inhibitors
Tojo, Shingo, Kohno, Tetsuya, Tanaka, Tomoyuki, Kamioka, Seiji, Ota, Yosuke, Ishii, Takayuki, Kamimoto, Keiko, Asano, Shigehiro, Isobe, Yoshiaki
Published in ACS medicinal chemistry letters (09.10.2014)
Published in ACS medicinal chemistry letters (09.10.2014)
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Journal Article
One-step assembling reaction to the pentacyclic acetal of pinnatoxins
Ishihara, J, Tojo, S, Kamikawa, A, Murai, A
Published in Chemical communications (Cambridge, England) (01.01.2001)
Published in Chemical communications (Cambridge, England) (01.01.2001)
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Journal Article
Abstract 3069: DSP-0692, a novel and selective stearoyl-CoA desaturase (SCD) inhibitor targeting cancer stem cells
Sugaru, Eiji, Furuta, Yudai, Fukunaga, Yuichi, Umehara, Hiroki, Otsubo, Tsuguteru, Watanabe, Manabu, Hasegawa, Futoshi, Tojo, Shingo, Hashizume, Miki, Ban, Hitoshi
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Journal Article
Abstract 3595: DSP-0692, a selective SCD inhibitor, enhances the anti-tumor activity of anti-PD1 antibody
Sugaru, Eiji, Furuta, Yudai, Nagagaki, Yoshikazu, Ikeda, Satoshi, Fukunaga, Yuichi, Umehara, Hiroki, Otsubo, Tsuguteru, Watanabe, Manabu, Tojo, Shingo, Hashizume, Miki, Matsuki, Yasushi, Ban, Hitoshi
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Journal Article
1,4-disubstituted imidazole derivative
Hasegawa, Futoshi, Ban, Hitoshi, Kusagi, Manabu, Hashizume, Miki, Tojo, Shingo
Year of Publication 30.05.2023
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Year of Publication 30.05.2023
Patent
AMINE DERIVATIVE
ASAMITSU, Yuko, WATANABE, Hitoshi, KAWAHATA, Wataru, URABE, Daisuke, MORIYAMA, Hideki, TOJO, Shingo
Year of Publication 02.10.2024
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Year of Publication 02.10.2024
Patent
AMINE DERIVATIVE
ASAMITSU, Yuko, WATANABE, Hitoshi, KAWAHATA, Wataru, URABE, Daisuke, MORIYAMA, Hideki, TOJO, Shingo
Year of Publication 12.09.2024
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Year of Publication 12.09.2024
Patent
NOVEL AMINE DERIVATIVES
ASAMITSU, Yuko, WATANABE, Hitoshi, KAWAHATA, Wataru, URABE, Daisuke, MORIYAMA, Hideki, TOJO, Shingo
Year of Publication 16.11.2023
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Year of Publication 16.11.2023
Patent
AMINE DERIVATIVE
ASAMITSU, Yuko, WATANABE, Hitoshi, KAWAHATA, Wataru, URABE, Daisuke, MORIYAMA, Hideki, TOJO, Shingo
Year of Publication 26.07.2023
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Year of Publication 26.07.2023
Patent
AMINE DERIVATIVE
ASAMITSU, Yuko, WATANABE, Hitoshi, KAWAHATA, Wataru, URABE, Daisuke, MORIYAMA, Hideki, TOJO, Shingo
Year of Publication 18.05.2023
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Year of Publication 18.05.2023
Patent
PURINE DERIVATIVES AS TLR7 INHIBITORS FOR TREATING E.G. SYSTEMIC LUPUS ERYTHEMATOSUS
ISOBE, Yoshiaki, FUJIWARA, Hiroaki, URABE, Daisuke, IDEUE, Eiji, TOJO, Shingo
Year of Publication 18.08.2021
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Year of Publication 18.08.2021
Patent
NOVEL ALKYNE DERIVATIVES
SAWA, Ayako, ASAMITSU, Yuko, KAWAHATA, Wataru, URABE, Daisuke, MORIYAMA, Hideki, SAWA, Masaaki, IWATA, Yasuhiro, TOJO, Shingo
Year of Publication 04.05.2023
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Year of Publication 04.05.2023
Patent
1,4-DISUBSTITUTED IMIDAZOLE DERIVATIVE
Hasegawa, Futoshi, Ban, Hitoshi, Kusagi, Manabu, Hashizume, Miki, Tojo, Shingo
Year of Publication 10.06.2021
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Year of Publication 10.06.2021
Patent
1,4-DISUBSTITUTED IMIDAZOLE DERIVATIVE
Hasegawa, Futoshi, Ban, Hitoshi, Kusagi, Manabu, Hashizume, Miki, Tojo, Shingo
Year of Publication 07.01.2021
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Year of Publication 07.01.2021
Patent
1,4-disubstituted imidazole derivative
Hasegawa, Futoshi, Ban, Hitoshi, Kusagi, Manabu, Hashizume, Miki, Tojo, Shingo
Year of Publication 20.10.2020
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Year of Publication 20.10.2020
Patent