Discovery of MDV6058 (PF-06952229), a selective and potent TGFβR1 inhibitor: Design, synthesis and optimization
Pujala, Brahmam, Ramachandran, Sreekanth A., Sonawane, Mukesh, Kamble, Maruti M., Panpatil, Dayanand, Adhikari, Swati, Soni, Sanjeev, Subbareddy, Venkata, Shinde, Bharat U., Nayak, Anjan K., Bansal, Chandni, Gupta, Ashu, Mukherjee, Kakoli, Agarwal, Anil K., Guerrero, Javier, Herrera, Francisco J., Bernales, Sebastian, Guha, Mausumee, Chakravarty, Sarvajit, Pham, Son M., Rai, Roopa
Published in Bioorganic & medicinal chemistry letters (01.11.2022)
Published in Bioorganic & medicinal chemistry letters (01.11.2022)
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Journal Article
Discovery of Pyrazolopyrimidine Derivatives as Novel Dual Inhibitors of BTK and PI3Kδ
Pujala, Brahmam, Agarwal, Anil K, Middya, Sandip, Banerjee, Monali, Surya, Arjun, Nayak, Anjan K, Gupta, Ashu, Khare, Sweta, Guguloth, Rambabu, Randive, Nitin A, Shinde, Bharat U, Thakur, Anamika, Patel, Dhananjay I, Raja, Mohd, Green, Michael J, Alfaro, Jennifer, Avila, Patricio, Pérez de Arce, Felipe, Almirez, Ramona G, Kanno, Stacy, Bernales, Sebastián, Hung, David T, Chakravarty, Sarvajit, McCullagh, Emma, Quinn, Kevin P, Rai, Roopa, Pham, Son M
Published in ACS medicinal chemistry letters (08.12.2016)
Published in ACS medicinal chemistry letters (08.12.2016)
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Journal Article
Discovery of MDV6058 (PF-06952229), a selective and potent TGF?R1 inhibitor: Design, synthesis and optimization
Pujala, Brahmam, Ramachandran, Sreekanth A., Sonawane, Mukesh, Kamble, Maruti M., Panpatil, Dayanand, Adhikari, Swati, Soni, Sanjeev, Subbareddy, Venkata, Shinde, Bharat U., Nayak, Anjan K., Bansal, Chandni, Gupta, Ashu, Mukherjee, Kakoli, Agarwal, Anil K., Guerrero, Javier, Herrera, Francisco J., Bernales, Sebastian, Guha, Mausumee, Chakravarty, Sarvajit, Pham, Son M., Rai, Roopa
Published in Bioorganic & medicinal chemistry letters (01.11.2022)
Published in Bioorganic & medicinal chemistry letters (01.11.2022)
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Journal Article