Scalable synthesis of bryostatin 1 and analogs, adjuvant leads against latent HIV
Wender, Paul A., Hardman, Clayton T., Ho, Stephen, Jeffreys, Matthew S., Maclaren, Jana K., Quiroz, Ryan V., Ryckbosch, Steven M., Shimizu, Akira J., Sloane, Jack L., Stevens, Matthew C.
Published in Science (American Association for the Advancement of Science) (13.10.2017)
Published in Science (American Association for the Advancement of Science) (13.10.2017)
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Journal Article
Characterization of designed, synthetically accessible bryostatin analog HIV latency reversing agents
Marsden, Matthew D., Wu, Xiaomeng, Navab, Sara M., Loy, Brian A., Schrier, Adam J., DeChristopher, Brian A., Shimizu, Akira J., Hardman, Clayton T., Ho, Stephen, Ramirez, Christina M., Wender, Paul A., Zack, Jerome A.
Published in Virology (New York, N.Y.) (01.07.2018)
Published in Virology (New York, N.Y.) (01.07.2018)
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Journal Article
Designed PKC-targeting bryostatin analogs modulate innate immunity and neuroinflammation
Abramson, Efrat, Hardman, Clayton, Shimizu, Akira J., Hwang, Soonmyung, Hester, Lynda D., Snyder, Solomon H., Wender, Paul A., Kim, Paul M., Kornberg, Michael D.
Published in Cell chemical biology (15.04.2021)
Published in Cell chemical biology (15.04.2021)
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Journal Article
Function-Oriented Synthesis: Design, Synthesis, and Evaluation of Highly Simplified Bryostatin Analogues
Wender, Paul A, Sloane, Jack L, Luu-Nguyen, Quang H, Ogawa, Yasuyuki, Shimizu, Akira J, Ryckbosch, Steven M, Tyler, Jefferson H, Hardman, Clayton
Published in Journal of organic chemistry (04.12.2020)
Published in Journal of organic chemistry (04.12.2020)
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Journal Article
Bryostatin 1 Promotes Synaptogenesis and Reduces Dendritic Spine Density in Cortical Cultures through a PKC-Dependent Mechanism
Ly, Calvin, Shimizu, Akira J, Vargas, Maxemiliano V, Duim, Whitney C, Wender, Paul A, Olson, David E
Published in ACS chemical neuroscience (03.06.2020)
Published in ACS chemical neuroscience (03.06.2020)
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Journal Article
APOL1 억제제로서의 4-페닐-2-(1H-1,2,3-트리아졸-4-일)피페리딘-4-올 유도체 및 이를 사용하는 방법
GARCIA BARRANTES PEDRO M, SENTER TIMOTHY J, SHIMIZU AKIRA J, DAKIN LESLIE A, BRODNEY MICHAEL A, DOLGIKH ELENA, STONE STEVEN D, MEDEK ALES, TSAY CHARLENE, OLSEN JESSICA H, DANIEL KEVIN B
Year of Publication 30.08.2024
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Year of Publication 30.08.2024
Patent
4-PHENYL-2-(1H-1,2,3-TRIAZOL-4-YL)PIPERIDIN-4-OL DERIVATIVES AS INHIBITORS OF APOL1 AND METHODS OF USING SAME
DOLGIKH, Elena, SENTER, Timothy J, MEDEK, Ales, BRODNEY, Michael A, GARCIA BARRANTES, Pedro M, OLSEN, Jessica H, STONE, Steven D, DANIEL, Kevin B, DAKIN, Leslie A, TSAY, Charlene, SHIMIZU, Akira J
Year of Publication 09.10.2024
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Year of Publication 09.10.2024
Patent
2-METHYL-4',5'-DIHYDROSPIRO[PIPERIDINE-4,7'-THIENO[2,3-C]PYRAN] DERIVATIVES AS INHIBITORS OF APOL1 AND METHODS OF USING SAME
CAO, Jingrong, WANG, Tiansheng, SENTER, Timothy J, KRUEGER, Elaine B, ANGLE, Samantha, GALE-DAY, Zachary, OLSEN, Jessica H, STONE, Steven D, COME, Jon, DAKIN, Leslie A, SHIMIZU, Akira J
Year of Publication 22.08.2024
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Year of Publication 22.08.2024
Patent
4',5'-DIHYDROSPIRO[PIPERIDINE-4,7'-THIENO[2,3-C]PYRAN] DERIVATIVES AS INHIBITORS OF APOL1 AND METHODS OF USING SAME
CAO, Jingrong, SENTER, Timothy J, WANG, Haoxuan, BRODNEY, Michael A, ANGLE, Samantha, OLSEN, Jessica H, STONE, Steven D, DOLGIKH, Elena, NANTHAKUMAR, Suganthini, KRUEGER, Elaine B, GALE-DAY, Zachary, COME, Jon, DAKIN, Leslie A, SHIMIZU, Akira J
Year of Publication 22.08.2024
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Year of Publication 22.08.2024
Patent
4-phenyl-2-(1h-1,2,3-triazol-4-yl)piperidin-4-ol derivatives as inhibitors of apol1 and methods of using same
SHIMIZU Akira J, DAKIN Leslie A, OLSEN Jessica H, SENTER Timothy J, TSAY Charlene, STONE Steven D, MEDEK Ales, DANIEL Kevin B, GARCIA BARRANTES Pedro M, BRODNEY Michael A, DOLGIKH Elena
Year of Publication 01.07.2024
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Year of Publication 01.07.2024
Patent