Effects of a farnesoid X receptor antagonist on hepatic lipid metabolism in primates
Amano, Yuichiro, Shimada, Mitsuyuki, Miura, Shotaro, Adachi, Ryutaro, Tozawa, Ryuichi
Published in European journal of pharmacology (15.01.2014)
Published in European journal of pharmacology (15.01.2014)
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Collaborative virtual screening to elaborate an imidazo[1,2-]pyridine hit series for visceral leishmaniasis
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Published in MedChemComm (01.04.2021)
Published in MedChemComm (01.04.2021)
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Antidyslipidemic potential of a novel farnesoid X receptor antagonist in a hamster model of dyslipidemia: Comparative studies of other nonstatin agents
Shinozawa, Emiko, Amano, Yuichiro, Yamakawa, Hiroko, Haba, Megumi, Shimada, Mitsuyuki, Tozawa, Ryuichi
Published in Pharmacology research & perspectives (01.04.2018)
Published in Pharmacology research & perspectives (01.04.2018)
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Novel Acyl Coenzyme A: Diacylglycerol Acyltransferase 1 Inhibitors—Synthesis and Biological Activities of N-(Substituted heteroaryl)-4-(substituted phenyl)-4-oxobutanamides
Nakada, Yoshihisa, Ogino, Masaki, Asano, Kouhei, Aoki, Kazuko, Miki, Hiroshi, Yamamoto, Toshihiro, Kato, Koki, Masago, Minori, Tamura, Norikazu, Shimada, Mitsuyuki
Published in Chemical & Pharmaceutical Bulletin (01.05.2010)
Published in Chemical & Pharmaceutical Bulletin (01.05.2010)
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Farnesoid X receptor antagonist exacerbates dyslipidemia in mice
Amano, Yuichiro, Yamakawa, Hiroko, Yonemori, Kazuko, Shimada, Mitsuyuki, Tozawa, Ryuichi
Published in Pharmacological reports (01.02.2018)
Published in Pharmacological reports (01.02.2018)
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Antidyslipidemic effects of a farnesoid X receptor antagonist in primates
Amano, Yuichiro, Shimada, Mitsuyuki, Miura, Shotaro, Adachi, Ryutaro, Tozawa, Ryuichi
Published in Life sciences (1973) (13.06.2014)
Published in Life sciences (1973) (13.06.2014)
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Collaborative Virtual Screening Identifies a 2‑Aryl-4-aminoquinazoline Series with Efficacy in an In Vivo Model of Trypanosoma cruzi Infection
Tawaraishi, Taisuke, Ochida, Atsuko, Akao, Yuichiro, Itono, Sachiko, Kamaura, Masahiro, Akther, Thamina, Shimada, Mitsuyuki, Canan, Stacie, Chowdhury, Sanjoy, Cao, Yafeng, Condroski, Kevin, Engkvist, Ola, Francisco, Amanda, Ghosh, Sunil, Kaki, Rina, Kelly, John M., Kimura, Chiaki, Kogej, Thierry, Nagaoka, Kazuya, Naito, Akira, Pairaudeau, Garry, Radu, Constantin, Roberts, Ieuan, Shum, David, Watanabe, Nao-aki, Xie, Huanxu, Yonezawa, Shuji, Yoshida, Osamu, Yoshida, Ryu, Mowbray, Charles, Perry, Benjamin
Published in Journal of medicinal chemistry (26.01.2023)
Published in Journal of medicinal chemistry (26.01.2023)
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Combinational effects of farnesoid X receptor antagonist and statin on plasma lipid levels and low-density lipoprotein clearance in guinea pigs
Amano, Yuichiro, Ishikawa, Eiichiro, Shinozawa, Emiko, Shimada, Mitsuyuki, Miura, Shotaro, Adachi, Ryutaro, Tozawa, Ryuichi
Published in Life sciences (1973) (11.07.2014)
Published in Life sciences (1973) (11.07.2014)
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Discovery of novel and selective IKK-β serine-threonine protein kinase inhibitors. Part 1
Murata, Toshiki, Shimada, Mitsuyuki, Sakakibara, Sachiko, Yoshino, Takashi, Kadono, Hiroshi, Masuda, Tsutomu, Shimazaki, Makoto, Shintani, Takuya, Fuchikami, Kinji, Sakai, Katsuya, Inbe, Hisayo, Takeshita, Keisuke, Niki, Toshiro, Umeda, Masaomi, Bacon, Kevin B., Ziegelbauer, Karl B., Lowinger, Timothy B.
Published in Bioorganic & medicinal chemistry letters (10.03.2003)
Published in Bioorganic & medicinal chemistry letters (10.03.2003)
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Pyrrolidinedione derivatives as antibacterial agents with a novel mode of action
Pohlmann, Jens, Lampe, Thomas, Shimada, Mitsuyuki, Nell, Peter G., Pernerstorfer, Josef, Svenstrup, Niels, Brunner, Nina A., Schiffer, Guido, Freiberg, Christoph
Published in Bioorganic & medicinal chemistry letters (15.02.2005)
Published in Bioorganic & medicinal chemistry letters (15.02.2005)
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Synthesis and structure–activity relationships of novel IKK-β inhibitors. Part 3: Orally active anti-inflammatory agents
Murata, Toshiki, Shimada, Mitsuyuki, Sakakibara, Sachiko, Yoshino, Takashi, Masuda, Tsutomu, Shintani, Takuya, Sato, Hiroki, Koriyama, Yuji, Fukushima, Keiko, Nunami, Noriko, Yamauchi, Megumi, Fuchikami, Kinji, Komura, Hiroshi, Watanabe, Akihiko, Ziegelbauer, Karl B, Bacon, Kevin B, Lowinger, Timothy B
Published in Bioorganic & medicinal chemistry letters (02.08.2004)
Published in Bioorganic & medicinal chemistry letters (02.08.2004)
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Journal Article
Synthesis and structure–activity relationships of novel IKK-β inhibitors. Part 2: Improvement of in vitro activity
Murata, Toshiki, Shimada, Mitsuyuki, Kadono, Hiroshi, Sakakibara, Sachiko, Yoshino, Takashi, Masuda, Tsutomu, Shimazaki, Makoto, Shintani, Takuya, Fuchikami, Kinji, Bacon, Kevin B, Ziegelbauer, Karl B, Lowinger, Timothy B
Published in Bioorganic & medicinal chemistry letters (02.08.2004)
Published in Bioorganic & medicinal chemistry letters (02.08.2004)
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Journal Article
Coenzyme A: Diacylglycerol acyltransferase 1 inhibitor ameliorates obesity, liver steatosis, and lipid metabolism abnormality in KKAy mice fed high-fat or high-carbohydrate diets
YAMAMOTO, Toshihiro, YAMAGUCHI, Hiroshi, KATO, Koki, MIKI, Hiroshi, SHIMADA, Mitsuyuki, NAKADA, Yoshihisa, OGINO, Masaki, ASANO, Kouhei, AOKI, Kazuko, TAMURA, Norikazu, MASAGO, Minori
Published in European journal of pharmacology (25.08.2010)
Published in European journal of pharmacology (25.08.2010)
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Journal Article
Coenzyme A: Diacylglycerol acyltransferase 1 inhibitor ameliorates obesity, liver steatosis, and lipid metabolism abnormality in KKA y mice fed high-fat or high-carbohydrate diets
Yamamoto, Toshihiro, Yamaguchi, Hiroshi, Miki, Hiroshi, Shimada, Mitsuyuki, Nakada, Yoshihisa, Ogino, Masaki, Asano, Kouhei, Aoki, Kazuko, Tamura, Norikazu, Masago, Minori, Kato, Koki
Published in European journal of pharmacology (25.08.2010)
Published in European journal of pharmacology (25.08.2010)
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Novel Acyl Coenzyme A
Nakada, Yoshihisa, Ogino, Masaki, Asano, Kouhei, Aoki, Kazuko, Miki, Hiroshi, Yamamoto, Toshihiro, Kato, Koki, Masago, Minori, Tamura, Norikazu, Shimada, Mitsuyuki
Published in Chemical & pharmaceutical bulletin (01.05.2010)
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Published in Chemical & pharmaceutical bulletin (01.05.2010)
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AMIDE COMPOUND
MASAGO, MINORI, NAKADA, YOSHIHISA, ASANO, KOUHEI, OGINO, MASAKI, TAMURA, NORIKAZU, SHIMADA, MITSUYUKI
Year of Publication 10.08.2006
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Year of Publication 10.08.2006
Patent
HETEROCYCLIC AMIDE COMPOUND AND USE THEREOF
TOZAWA, RYUICHI, NAKADA, YOSHIHISA, MARUI, SHOGO, FUNABASHI, YASUNORI, MIURA, SHOTARO, TAMURA, NORIKAZU, SAKAMOTO, JUNICHI, HOSONO, HIROSHI, SHIMADA, MITSUYUKI
Year of Publication 10.05.2007
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Year of Publication 10.05.2007
Patent
Erratum to “Discovery of novel and selective IKK-β serine-threonine protein kinase inhibitors. Part 1”
Murata, Toshiki, Shimada, Mitsuyuki, Sakakibara, Sachiko, Yoshino, Takashi, Kadono, Kiroshi, Masuda, Tsutomu, Shimazaki, Makoto, Shintani, Takuya, Fuchikami, Kinji, Sakai, Katsuya, Inbe, Hisayo, Takeshita, Keisuke, Niki, Toshiro, Umeda, Masaomi, Bacon, Kevin B., Ziegelbauer, Karl B., Lowinger, Timothy B.
Published in Bioorganic & medicinal chemistry letters (01.10.2003)
Published in Bioorganic & medicinal chemistry letters (01.10.2003)
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Journal Article
FUSED AZOLE-PYRIMIDINE DERIVATIVES
KATO ISSEI, URBAHNS KLAUS, BACON KEVIN, GANTNER FLORIAN, TSUJISHITA HIDEKI, MIURA MAMI, SHIMADA MITSUYUKI, OMORI NAOKI, FUCHIKAMI KINJI, MURATA TOSHIKI
Year of Publication 31.08.2017
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Year of Publication 31.08.2017
Patent