Trimethylamine N‐Oxide Promotes Vascular Inflammation Through Signaling of Mitogen‐Activated Protein Kinase and Nuclear Factor‐κB
Seldin, Marcus M., Meng, Yonghong, Qi, Hongxiu, Zhu, WeiFei, Wang, Zeneng, Hazen, Stanley L., Lusis, Aldons J., Shih, Diana M.
Published in Journal of the American Heart Association (01.02.2016)
Published in Journal of the American Heart Association (01.02.2016)
Get full text
Journal Article
Trimethylamine-N-Oxide, a Metabolite Associated with Atherosclerosis, Exhibits Complex Genetic and Dietary Regulation
Bennett, Brian J., Vallim, Thomas Q. de Aguiar, Wang, Zeneng, Shih, Diana M., Meng, Yonghong, Gregory, Jill, Allayee, Hooman, Lee, Richard, Graham, Mark, Crooke, Rosanne, Edwards, Peter A., Hazen, Stanley L., Lusis, Aldons J.
Published in Cell metabolism (08.01.2013)
Published in Cell metabolism (08.01.2013)
Get full text
Journal Article
Flavin containing monooxygenase 3 exerts broad effects on glucose and lipid metabolism and atherosclerosis[S]
Shih, Diana M., Wang, Zeneng, Lee, Richard, Meng, Yonghong, Che, Nam, Charugundla, Sarada, Qi, Hannah, Wu, Judy, Pan, Calvin, Brown, J. Mark, Vallim, Thomas, Bennett, Brian J., Graham, Mark, Hazen, Stanley L., Lusis, Aldons J.
Published in Journal of lipid research (01.01.2015)
Published in Journal of lipid research (01.01.2015)
Get full text
Journal Article
Inhibition of microbiota-dependent TMAO production attenuates chronic kidney disease in mice
Zhang, Wenchao, Miikeda, Aika, Zuckerman, Jonathan, Jia, Xun, Charugundla, Sarada, Zhou, Zhiqiang, Kaczor-Urbanowicz, Karolina Elżbieta, Magyar, Clara, Guo, Fangfei, Wang, Zeneng, Pellegrini, Matteo, Hazen, Stanley L, Nicholas, Susanne B, Lusis, Aldons J, Shih, Diana M
Published in Scientific reports (12.01.2021)
Published in Scientific reports (12.01.2021)
Get full text
Journal Article
Suppression of inflammatory arthritis in human serum paraoxonase 1 transgenic mice
Charles-Schoeman, Christina, Wang, Jennifer, Shahbazian, Ani, Lee, Yuen Yin, Wang, Xiaoyan, Grijalva, Victor, Brahn, Ernest, Shih, Diana M, Devarajan, Asokan, Montano, Christy, Lusis, Aldons J, Reddy, Srinivasa T
Published in Scientific reports (08.10.2020)
Published in Scientific reports (08.10.2020)
Get full text
Journal Article
NOTUM promotes thermogenic capacity and protects against diet-induced obesity in male mice
Guo, Fangfei, Seldin, Marcus, Péterfy, Miklós, Charugundla, Sarada, Zhou, Zhiqiang, Lee, Stephen D., Mouton, Alice, Rajbhandari, Prashant, Zhang, Wenchao, Pellegrini, Matteo, Tontonoz, Peter, Lusis, Aldons J., Shih, Diana M.
Published in Scientific reports (12.08.2021)
Published in Scientific reports (12.08.2021)
Get full text
Journal Article
Web Resource
Human and murine paraoxonase 1 are host modulators of Pseudomonas aeruginosa quorum-sensing
Ozer, Egon A., Pezzulo, Alejandro, Shih, Diana M., Chun, Carlene, Furlong, Clement, Lusis, Aldons J., Greenberg, Everett P., Zabner, Joseph
Published in FEMS microbiology letters (01.12.2005)
Published in FEMS microbiology letters (01.12.2005)
Get full text
Journal Article
A Common Mutation in Paraoxonase-2 Results in Impaired Lactonase Activity
Stoltz, David A., Ozer, Egon A., Recker, Thomas J., Estin, Miriam, Yang, Xia, Shih, Diana M., Lusis, Aldons J., Zabner, Joseph
Published in The Journal of biological chemistry (18.12.2009)
Published in The Journal of biological chemistry (18.12.2009)
Get full text
Journal Article
Paraoxonase-2 Modulates Stress Response of Endothelial Cells to Oxidized Phospholipids and a Bacterial Quorum–Sensing Molecule
Kim, Juyong Brian, Xia, Yu-Rong, Romanoski, Casey E, Lee, Sangderk, Meng, YongHong, Shi, Yi-Shou, Bourquard, Noam, Gong, Ke Wei, Port, Zachary, Grijalva, Victor, Reddy, Srinivasa T, Berliner, Judith A, Lusis, Aldons J, Shih, Diana M
Published in Arteriosclerosis, thrombosis, and vascular biology (01.11.2011)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.11.2011)
Get full text
Journal Article
Paraoxonase-1 Inhibits Oxidized Low-Density Lipoprotein-Induced Metabolic Alterations and Apoptosis in Endothelial Cells: A Nondirected Metabolomic Study
Shih, Diana M., Joven, Jorge, Camps, Jordi, García-Heredia, Anabel, Mackness, Michael, Mackness, Bharti, Fort, Isabel, Marsillach, Judit, Rull, Anna, Triguero, Iris
Published in Mediators of Inflammation (01.01.2013)
Published in Mediators of Inflammation (01.01.2013)
Get full text
Journal Article
PON2 Deficiency Leads to Increased Susceptibility to Diet-Induced Obesity
Shih, Diana M, Meng, Yonghong, Sallam, Tamer, Vergnes, Laurent, Shu, Michelle L, Reue, Karen, Tontonoz, Peter, Fogelman, Alan M, Lusis, Aldons J, Reddy, Srinivasa T
Published in Antioxidants (11.01.2019)
Published in Antioxidants (11.01.2019)
Get full text
Journal Article
Mice lacking serum paraoxonase are susceptible to organophosphate toxicity and atherosclerosis
Lusis, Aldons J, Shih, Diana M, Gu, Lingjie, Xia, Yu-Rong, Navab, Mohamad, Li, Wan-Fen, Hama, Susan, Castellani, Lawrence W, Furlong, Clement E, Costa, Lucio G, Fogelman, Alan M
Published in Nature (London) (16.07.1998)
Published in Nature (London) (16.07.1998)
Get full text
Journal Article
Toxicity of chlorpyrifos and chlorpyrifos oxon in a transgenic mouse model of the human paraoxonase (PON1) Q192R polymorphism
Cole, Toby B, Walter, Betsy J, Shih, Diana M, Tward, Aaron D, Lusis, Aldons J, Timchalk, Charles, Richter, Rebecca J, Costa, Lucio G, Furlong, Clement E
Published in Pharmacogenetics and genomics (01.08.2005)
Published in Pharmacogenetics and genomics (01.08.2005)
Get more information
Journal Article
Mechanisms underlying adverse effects of HDL on eNOS-activating pathways in patients with coronary artery disease
Besler, Christian, Heinrich, Kathrin, Rohrer, Lucia, Doerries, Carola, Riwanto, Meliana, Shih, Diana M, Chroni, Angeliki, Yonekawa, Keiko, Stein, Sokrates, Schaefer, Nicola, Mueller, Maja, Akhmedov, Alexander, Daniil, Georgios, Manes, Costantina, Templin, Christian, Wyss, Christophe, Maier, Willibald, Tanner, Felix C, Matter, Christian M, Corti, Roberto, Furlong, Clement, Lusis, Aldons J, von Eckardstein, Arnold, Fogelman, Alan M, Lüscher, Thomas F, Landmesser, Ulf
Published in The Journal of clinical investigation (01.07.2011)
Published in The Journal of clinical investigation (01.07.2011)
Get full text
Journal Article
Genetic Deficiency of Flavin-Containing Monooxygenase 3 (Fmo3) Protects Against Thrombosis but Has Only a Minor Effect on Plasma Lipid Levels—Brief Report
Shih, Diana M, Zhu, Weifei, Schugar, Rebecca C, Meng, Yonghong, Jia, Xun, Miikeda, Aika, Wang, Zeneng, Zieger, Marina, Lee, Richard, Graham, Mark, Allayee, Hooman, Cantor, Rita M, Mueller, Christian, Brown, J Mark, Hazen, Stanley L, Lusis, Aldons J
Published in Arteriosclerosis, thrombosis, and vascular biology (01.06.2019)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.06.2019)
Get full text
Journal Article