Discovery of novel forkhead box O1 inhibitors for treating type 2 diabetes: improvement of fasting glycemia in diabetic db/db mice
Nagashima, Takeyuki, Shigematsu, Nobuharu, Maruki, Riyo, Urano, Yasuharu, Tanaka, Hirotsugu, Shimaya, Akiyoshi, Shimokawa, Teruhiko, Shibasaki, Masayuki
Published in Molecular pharmacology (01.11.2010)
Published in Molecular pharmacology (01.11.2010)
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Neamphamide A, a New HIV-Inhibitory Depsipeptide from the Papua New Guinea Marine Sponge Neamphius huxleyi
Oku, Naoya, Gustafson, Kirk R, Cartner, Laura K, Wilson, Jennifer A, Shigematsu, Nobuharu, Hess, Sonja, Pannell, Lewis K, Boyd, Michael R, McMahon, James B
Published in Journal of natural products (Washington, D.C.) (01.08.2004)
Published in Journal of natural products (Washington, D.C.) (01.08.2004)
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Cloning and heterologous expression of P450Um-1, a novel bacterial P450 gene, for hydroxylation of immunosuppressive agent AS1387392
Ueno, Motoi, Sasamura, Satoshi, Yamashita, Midori, Shigematsu, Nobuharu, Hashimoto, Michizane, Hino, Motohiro, Fujie, Akihiko
Published in Journal of antibiotics (01.11.2010)
Published in Journal of antibiotics (01.11.2010)
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Papuamides A−D, HIV-Inhibitory and Cytotoxic Depsipeptides from the Sponges Theonella mirabilis and Theonella swinhoei Collected in Papua New Guinea
FORD, Paul W., GUSTAFSON, Kirk R., MCKEE, Tawnya C., SHIGEMATSU, Nobuharu, MAURIZI, Laura K., PANNELL, Lewis K., WILLIAMS, David E., DILIP DE SILVA, E., LASSOTA, Peter, ALLEN, Theresa M., VAN SOEST, Rob, ANDERSEN, Raymond J., BOYD, Michael R.
Published in Journal of the American Chemical Society (30.06.1999)
Published in Journal of the American Chemical Society (30.06.1999)
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Microspinosamide, a New HIV-Inhibitory Cyclic Depsipeptide from the Marine Sponge Sidonops microspinosa
RASHID, Mohammad A., GUSTAFSON, Kirk R., CARTNER, Laura K., SHIGEMATSU, Nobuharu, PANNELL, Lewis K., BOYD, Michael R.
Published in Journal of natural products (Washington, D.C.) (01.01.2001)
Published in Journal of natural products (Washington, D.C.) (01.01.2001)
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The Novel Gluconeogenesis Inhibitors FR225659 and FR225656 from Helicomyces sp. No. 19353: III. Structure Determination
ZENKOH, TATSUYA, OHTSU, YOSHIHIRO, YOSHIMURA, SEIJI, SHIGEMATSU, NOBUHARU, TAKASE, SHIGEHIRO, HINO, MOTOHIRO
Published in Journal of antibiotics (01.08.2003)
Published in Journal of antibiotics (01.08.2003)
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FR901483, a Novel Immunosuppressant Isolated from Cladobotryum sp. No. 11231: Taxonomy of the Producing Organism, Fermentation, Isolation, Physico-chemical Properties and Biological Activities
SAKAMOTO, KAZUTOSHI, TSUJII, EISAKU, ABE, FUMIE, NAKANISHI, TOMOKO, YAMASHITA, MICHIO, SHIGEMATSU, NOBUHARU, IZUMI, SHIZUE, OKUHARA, MASAKUNI
Published in Journal of antibiotics (01.01.1996)
Published in Journal of antibiotics (01.01.1996)
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FR901228, A NOVEL ANTITUMOR BICYCLIC DEPSIPEPTIDE PRODUCED BY Chromobacterium violaceum No. 968: II. STRUCTURE DETERMINATION
SHIGEMATSU, NOBUHARU, UEDA, HIROTSUGU, TAKASE, SHIGEHIRO, TANAKA, HIROKAZU, YAMAMOTO, KYOKO, TADA, TOSHUIJI
Published in Journal of antibiotics (1994)
Published in Journal of antibiotics (1994)
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FR225659-binding Proteins: Identification as Serine/Threonine Protein Phosphatase PP1 and PP2A Using High-performance Affinity Beads
HATORI, HIDETAKA, ZENKOH, TATSUYA, KOBAYASHI, MOTOO, OHTSU, YOSHIHIRO, SHIGEMATSU, NOBUHARU, SETOI, HIROYUKI, HINO, MOTOHIRO, HANDA, HIROSHI
Published in Journal of antibiotics (01.07.2004)
Published in Journal of antibiotics (01.07.2004)
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WF11899A, B AND C, NOVEL ANTIFUNGAL LIPOPEPTIDES: I. TAXONOMY, FERMENTATION, ISOLATION AND PHYSICO-CHEMICAL PROPERTIES
IWAMOTO, TOSHIRO, FUJIE, AKIHIKO, SAKAMOTO, KAZUTOSHI, TSURUMI, YASUHISA, SHIGEMATSU, NOBUHARU, YAMASHITA, MICHIO, HASHIMOTO, SEIJI, OKUHARA, MASAKUNI, KOHSAKA, MASANOBU
Published in Journal of antibiotics (1994)
Published in Journal of antibiotics (1994)
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FR901469, a Novel Antifungal Antibiotic from an Unidentified Fungus No. 11243: III. Structure Determination
FUJIE, AKIHIKO, MURAMATSU, HIDEYUKI, YOSHIMURA, SEIJI, HASHIMOTO, MICHIZANE, SHIGEMATSU, NOBUHARU, TAKASE, SHIGEHIRO
Published in Journal of antibiotics (01.07.2001)
Published in Journal of antibiotics (01.07.2001)
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Site-specific Structural Transformation of the Novel Antifungal Cycle Depsipeptide FR901469. Synthesis and Biological Activity of FR203903
TANAKA, AKIRA, BARRETT, DAVID, FUJIE, AKIHIKO, SHIGEMATSU, NOBUHARU, HASHIMOTO, MICHIZANE, HASHIMOTO, SEIJI, IKEDA, FUMIAKI
Published in Journal of antibiotics (2001)
Published in Journal of antibiotics (2001)
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A NOVEL ANTIFUNGAL ANTIBIOTIC, FR-900848: I. PRODUCTION, ISOLATION, PHYSICO-CHEMICAL AND BIOLOGICAL PROPERTIES
YOSHIDA, MASARU, EZAKI, MASAMI, HASHIMOTO, MICHIZANE, YAMASHITA, MICHIO, SHIGEMATSU, NOBUHARU, OKUHARA, MASAKUNI, KOHSAKA, MASANOBU, HORIKOSHI, KOKI
Published in Journal of antibiotics (1990)
Published in Journal of antibiotics (1990)
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WS79089A, B AND C, NEW ENDOTHELIN CONVERTING ENZYME INHIBITORS ISOLATED FROM Streptosporangium roseum. NO. 79089: TAXONOMY, FERMENTATION, ISOLATION, PHYSICO-CHEMICAL PROPERTIES AND BIOLOGICAL ACTIVITIES
TSURUMI, YASUHISA, OHHATA, NOBUTAKA, IWAMOTO, TOSHIRO, SHIGEMATSU, NOBUHARU, SAKAMOTO, KAZUTOSHI, NISHIKAWA, MOTOAKI, KIYOTO, SUMIO, OKUHARA, MASAKUNI
Published in Journal of antibiotics (1994)
Published in Journal of antibiotics (1994)
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Structure of WS9326A, a novel tachykinin antagonist from a Streptomyces
Shigematsu, Nobuharu, Hayashi, Kenichi, Kayakiri, Natsuko, Takase, Shigehiro, Hashimoto, Masashi, Tanaka, Hirokazu
Published in Journal of organic chemistry (01.01.1993)
Published in Journal of organic chemistry (01.01.1993)
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WS9326A, A NOVEL TACHYKININ ANTAGONIST ISOLATED FROM Streptomyces violaceusniger No. 9326: I. TAXONOMY, FERMENTATION, ISOLATION, PHYSICO-CHEMICAL PROPERTIES AND BIOLOGICAL ACTIVITIES
HAYASHI, KENICHI, HASHIMOTO, MICHIZANE, SHIGEMATSU, NOBUHARU, NISHIKAWA, MOTOAKI, EZAKI, MASAMI, YAMASHITA, MICHIO, KIYOTO, SUMIO, OKUHARA, MASAKUNI, KOHSAKA, MASANOBU, IMANAKA, HIROSHI
Published in Journal of antibiotics (1992)
Published in Journal of antibiotics (1992)
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BIPHENOMYCIN C, A PRECURSOR OF BIPHENOMYCIN A IN MIXED CULTURE
EZAKI, MASAMI, SHIGEMATSU, NOBUHARU, YAMASHITA, MICHIO, KOMORI, TADAAKI, UMEHARA, KAZUYOSHI, IMANAKA, HIROSHI
Published in Journal of antibiotics (01.01.1993)
Published in Journal of antibiotics (01.01.1993)
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R1128 SUBSTANCES, NOVEL NON-STEROIDAL ESTROGEN-RECEPTOR ANTAGONISTS PRODUCED BY A Streptomyces: II. PHYSICO-CHEMICAL PROPERTIES AND STRUCTURE DETERMINATION
HORI, YASUHIRO, TAKASE, SHIGEHIRO, SHIGEMATSU, NOBUHARU, GOTO, TOSHIO, OKUHARA, MASAKUNI, KOHSAKA, MASANOBU
Published in Journal of antibiotics (1993)
Published in Journal of antibiotics (1993)
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Structure of WS-43708A, a novel cyclic peptide antibiotic
Uchida, Itsuo, Ezaki, Masami, Shigematsu, Nobuharu, Hashimoto, Masashi
Published in Journal of organic chemistry (01.04.1985)
Published in Journal of organic chemistry (01.04.1985)
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