K-Ras(G12D)-selective inhibitory peptides generated by random peptide T7 phage display technology
Sakamoto, Kotaro, Kamada, Yusuke, Sameshima, Tomoya, Yaguchi, Masahiro, Niida, Ayumu, Sasaki, Shigekazu, Miwa, Masanori, Ohkubo, Shoichi, Sakamoto, Jun-ichi, Kamaura, Masahiro, Cho, Nobuo, Tani, Akiyoshi
Published in Biochemical and biophysical research communications (11.03.2017)
Published in Biochemical and biophysical research communications (11.03.2017)
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Abnormal thyroid hormone response to TRH in a case of macro-TSH and the cut-off value for screening cases of inappropriate TSH elevation
Ohba, Kenji, Maekawa, Masato, Iwahara, Kunihiro, Suzuki, Yasuhide, Matsushita, Akio, Sasaki, Shigekazu, Oki, Yutaka, Nakamura, Hirotoshi
Published in ENDOCRINE JOURNAL (01.01.2020)
Published in ENDOCRINE JOURNAL (01.01.2020)
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Clinical outcomes of 34 patients with resistance to thyroid hormone beta: a twenty-year experience in Japan
Ohba, Kenji, Sasaki, Shigekazu, Nakamura, Hiroko Misawa, Matsushita, Akio, Kuroda, Go, Sakai, Yuki, Nakamura, Hirotoshi
Published in Endocrine Journal (01.01.2022)
Published in Endocrine Journal (01.01.2022)
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Investigation of the structural requirements of K-Ras(G12D) selective inhibitory peptide KRpep-2d using alanine scans and cysteine bridging
Niida, Ayumu, Sasaki, Shigekazu, Yonemori, Kazuko, Sameshima, Tomoya, Yaguchi, Masahiro, Asami, Taiji, Sakamoto, Kotaro, Kamaura, Masahiro
Published in Bioorganic & medicinal chemistry letters (15.06.2017)
Published in Bioorganic & medicinal chemistry letters (15.06.2017)
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Discovery of an Orally Bioavailable, Brain-Penetrating, in Vivo Active Phosphodiesterase 2A Inhibitor Lead Series for the Treatment of Cognitive Disorders
Mikami, Satoshi, Sasaki, Shigekazu, Asano, Yasutomi, Ujikawa, Osamu, Fukumoto, Shoji, Nakashima, Kosuke, Oki, Hideyuki, Kamiguchi, Naomi, Imada, Haruka, Iwashita, Hiroki, Taniguchi, Takahiko
Published in Journal of medicinal chemistry (28.09.2017)
Published in Journal of medicinal chemistry (28.09.2017)
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A Case of 17α-hydroxylase/17,20-lyase Deficiency Diagnosed at 45 Years of Age with Hyperaldosteronism
Ikeya, Akira, Yamashita, Miho, Kakizawa, Keisuke, Kawauchi, Yuto, Matsushita, Akio, Fujisawa, Yasuko, Ogata, Tsutomu, Sasaki, Shigekazu
Published in Internal Medicine (2024)
Published in Internal Medicine (2024)
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Influence of thyroid dysfunction on brain natriuretic peptide level in health examination participants
Ohba, Kenji, Okada, Eisaku, Goto, Yoshie, Suzuki, Sadako, Machii, Masashi, Nonaka, Daishi, Matsushita, Akio, Sasaki, Shigekazu, Suda, Takafumi, Oki, Yutaka, Takase, Hiroyuki
Published in ENDOCRINE JOURNAL (01.01.2020)
Published in ENDOCRINE JOURNAL (01.01.2020)
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Impairment of the Hypothalamus–Pituitary–Thyroid Axis Caused by Naturally Occurring GATA2 Mutations In Vitro
Sakai, Yuki, Ohba, Kenji, Sasaki, Shigekazu, Matsushita, Akio, Nakamura, Hiroko Misawa, Kuroda, Go, Tsuriya, Daisuke, Yamashita, Miho, Suda, Takafumi
Published in International journal of molecular sciences (16.09.2021)
Published in International journal of molecular sciences (16.09.2021)
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CCNB2 and AURKA overexpression may cause atypical mitosis in Japanese cortisol-producing adrenocortical carcinoma with TP53 somatic variant
Ikeya, Akira, Nakashima, Mitsuko, Yamashita, Miho, Kakizawa, Keisuke, Okawa, Yuta, Saitsu, Hirotomo, Sasaki, Shigekazu, Sasano, Hironobu, Suda, Takafumi, Oki, Yutaka
Published in PloS one (14.04.2020)
Published in PloS one (14.04.2020)
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G ATA2 mediates the negative regulation of the prepro-thyrotropin-releasing hormone gene by liganded T3 receptor β2 in the rat hypothalamic paraventricular nucleus
Kuroda, Go, Sasaki, Shigekazu, Matsushita, Akio, Ohba, Kenji, Sakai, Yuki, Shinkai, Shinsuke, Nakamura, Hiroko Misawa, Yamagishi, Satoru, Sato, Kohji, Hirahara, Naoko, Oki, Yutaka, Ito, Masahiko, Suzuki, Tetsuro, Suda, Takafumi
Published in PloS one (17.11.2020)
Published in PloS one (17.11.2020)
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G-protein-coupled receptor 40 agonist GW9508 potentiates glucose-stimulated insulin secretion through activation of protein kinase Cα and ε in INS-1 cells
Hashimoto, Takuya, Mogami, Hideo, Tsuriya, Daisuke, Morita, Hiroshi, Sasaki, Shigekazu, Kumada, Tatsuro, Suzuki, Yuko, Urano, Tetsumei, Oki, Yutaka, Suda, Takafumi
Published in PloS one (09.09.2019)
Published in PloS one (09.09.2019)
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Liganded T3 receptor β2 inhibits the positive feedback autoregulation of the gene for GATA2, a transcription factor critical for thyrotropin production
Hirahara, Naoko, Nakamura, Hiroko Misawa, Sasaki, Shigekazu, Matsushita, Akio, Ohba, Kenji, Kuroda, Go, Sakai, Yuki, Shinkai, Shinsuke, Haeno, Hiroshi, Nishio, Takuhiro, Yoshida, Shuichi, Oki, Yutaka, Suda, Takafumi
Published in PloS one (01.01.2020)
Published in PloS one (01.01.2020)
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A case of TSH-secreting pituitary adenoma with cyclic fluctuations in serum TSH levels
Okuma, Hideyuki, Hashimoto, Koshi, Ohashi, Takuya, Mihara, Masatomo, Minami, Isao, Izumiyama, Hajime, Sasaki, Shigekazu, Inoshita, Naoko, Nishioka, Hiroshi, Yamada, Shozo, Yoshimoto, Takanobu
Published in Endocrine Journal (01.01.2018)
Published in Endocrine Journal (01.01.2018)
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Essential role of TEA domain transcription factors in the negative regulation of the MYH 7 gene by thyroid hormone and its receptors
Iwaki, Hiroyuki, Sasaki, Shigekazu, Matsushita, Akio, Ohba, Kenji, Matsunaga, Hideyuki, Misawa, Hiroko, Oki, Yutaka, Ishizuka, Keiko, Nakamura, Hirotoshi, Suda, Takafumi
Published in PloS one (01.04.2014)
Published in PloS one (01.04.2014)
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Essential Role of GATA2 in the Negative Regulation of Type 2 Deiodinase Gene by Liganded Thyroid Hormone Receptor β2 in Thyrotroph
Matsunaga, Hideyuki, Sasaki, Shigekazu, Suzuki, Shingo, Matsushita, Akio, Nakamura, Hirotoshi, Nakamura, Hiroko Misawa, Hirahara, Naoko, Kuroda, Go, Iwaki, Hiroyuki, Ohba, Kenji, Morita, Hiroshi, Oki, Yutaka, Suda, Takafumi
Published in PloS one (16.11.2015)
Published in PloS one (16.11.2015)
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Intractable disseminated maculopapular eruption in a patient with granulocyte macrophage colony‐stimulating factor‐producing anaplastic thyroid carcinoma
Kasuya, Akira, Shinkai, Shinsuke, Sakamoto, Sayuri, Phadungsaksawasdi, Pawit, Shimauchi, Takatoshi, Hosokawa, Seiji, Imai, Atsushi, Sasaki, Shigekazu, Oki, Yutaka, Tokura, Yoshiki
Published in Journal of dermatology (01.11.2019)
Published in Journal of dermatology (01.11.2019)
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High incidence of thyroid cancer in focal thyroid incidentaloma detected by 18F-fluorodexyglucose positron emission tomography in relatively young healthy subjects: results of 3-year follow-up
Ohba, Kenji, Nishizawa, Sadahiko, Matsushita, Akio, Inubushi, Masayuki, Nagayama, Koji, Iwaki, Hiroyuki, Matsunaga, Hideyuki, Suzuki, Shingo, Sasaki, Shigekazu, Oki, Yutaka, Okada, Hiroyuki, Nakamura, Hirotoshi
Published in ENDOCRINE JOURNAL (2010)
Published in ENDOCRINE JOURNAL (2010)
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GATA2 mediates thyrotropin-releasing hormone-induced transcriptional activation of the thyrotropin β gene
Ohba, Kenji, Sasaki, Shigekazu, Matsushita, Akio, Iwaki, Hiroyuki, Matsunaga, Hideyuki, Suzuki, Shingo, Ishizuka, Keiko, Misawa, Hiroko, Oki, Yutaka, Nakamura, Hirotoshi
Published in PloS one (14.04.2011)
Published in PloS one (14.04.2011)
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