Comparative Evaluation of Plasma Bile Acids, Dehydroepiandrosterone Sulfate, Hexadecanedioate, and Tetradecanedioate with Coproporphyrins I and III as Markers of OATP Inhibition in Healthy Subjects
Shen, Hong, Chen, Weiqi, Drexler, Dieter M, Mandlekar, Sandhya, Holenarsipur, Vinay K, Shields, Eric E, Langish, Robert, Sidik, Kurex, Gan, Jinping, Humphreys, W Griffith, Marathe, Punit, Lai, Yurong
Published in Drug metabolism and disposition (01.08.2017)
Published in Drug metabolism and disposition (01.08.2017)
Get full text
Journal Article
Development of BET inhibitors as potential treatments for cancer: A search for structural diversity
Hill, Matthew D., Fang, Haiquan, Tokarski, John, Fanslau, Carolynn, Haarhoff, Zuzana, Huang, Christine, Kramer, Melissa, Menard, Krista, Monereau, Laura, Morrison, John, Ranasinghe, Asoka, Shields, Eric E., Tye, Ching Kim, Westhouse, Richard, Everlof, Gerry, Sheriff, Steven, Yan, Chunhong, Marsilio, Frank, Zhang, Lisa, Zvyaga, Tatyana, Lee, Francis, Gavai, Ashvinikumar V., Degnan, Andrew P.
Published in Bioorganic & medicinal chemistry letters (15.07.2021)
Published in Bioorganic & medicinal chemistry letters (15.07.2021)
Get full text
Journal Article
The utility of stable isotope labeled (SIL) analogues in the bioanalysis of endogenous compounds by LC-MS applied to the study of bile acids in a metabolomics assay
Zheng, Joanna J., Shields, Eric E., Snow, Kimberly J., Nelson, David M., Olah, Timothy V., Reily, Michael D., Robertson, Donald G., Shipkova, Petia A., Stryker, Steven A., Xin, Baomin, Drexler, Dieter M.
Published in Analytical biochemistry (15.06.2016)
Published in Analytical biochemistry (15.06.2016)
Get full text
Journal Article
Oxazolidinone-based allosteric modulators of mGluR5: Defining molecular switches to create a pharmacological tool box
Huang, Hong, Degnan, Andrew P., Balakrishnan, Anand, Easton, Amy, Gulianello, Michael, Huang, Yanling, Matchett, Michele, Mattson, Gail, Miller, Regina, Santone, Kenneth S., Senapati, Arun, Shields, Eric E., Sivarao, Digavalli V., Snyder, Lawrence B., Westphal, Ryan, Whiterock, Valerie J., Yang, Fukang, Bronson, Joanne J., Macor, John E.
Published in Bioorganic & medicinal chemistry letters (01.09.2016)
Published in Bioorganic & medicinal chemistry letters (01.09.2016)
Get full text
Journal Article
Development of BET Inhibitors as Potential Treatments for Cancer: Optimization of Pharmacokinetic Properties
Hill, Matthew D., Fang, Haiquan, Norris, Derek, Delucca, George V., Huang, Hong, DeBenedetto, Mikkel, Quesnelle, Claude, Schmitz, William D., Tokarski, John S., Sheriff, Steven, Yan, Chunhong, Fanslau, Caroline, Haarhoff, Zuzana, Huang, Christine, Kramer, Melissa, Madari, Shilpa, Menard, Krista, Monereau, Laura, Morrison, John, Raghavan, Nirmala, Shields, Eric E., Simmermacher-Mayer, Jean, Sinz, Michael, Tye, Ching Kim, Westhouse, Richard, Xie, Chunshan, Zhang, Haiying, Zhang, Lisa, Zvyaga, Tatyana, Lee, Francis, Gavai, Ashvinikumar V., Degnan, Andrew P.
Published in ACS medicinal chemistry letters (14.07.2022)
Published in ACS medicinal chemistry letters (14.07.2022)
Get full text
Journal Article
Difluorocyclobutylacetylenes as positive allosteric modulators of mGluR5 with reduced bioactivation potential
Degnan, Andrew P., Maxwell, Darrell, Balakrishnan, Anand, Brown, Jeffrey M., Easton, Amy, Gulianello, Michael, Hanumegowda, Umesh, Hill-Drzewi, Melissa, Miller, Regina, Santone, Kenneth S., Senapati, Arun, Shields, Eric E., Sivarao, Digavalli V., Westphal, Ryan, Whiterock, Valerie J., Zhuo, Xiaoliang, Bronson, Joanne J., Macor, John E.
Published in Bioorganic & medicinal chemistry letters (15.12.2016)
Published in Bioorganic & medicinal chemistry letters (15.12.2016)
Get full text
Journal Article
Discovery and Preclinical Evaluation of BMS-955829, a Potent Positive Allosteric Modulator of mGluR5
Yang, Fukang, Snyder, Lawrence B, Balakrishnan, Anand, Brown, Jeffrey M, Sivarao, Digavalli V, Easton, Amy, Fernandes, Alda, Gulianello, Michael, Hanumegowda, Umesh M, Huang, Hong, Huang, Yanling, Jones, Kelli M, Li, Yu-Wen, Matchett, Michele, Mattson, Gail, Miller, Regina, Santone, Kenneth S, Senapati, Arun, Shields, Eric E, Simutis, Frank J, Westphal, Ryan, Whiterock, Valerie J, Bronson, Joanne J, Macor, John E, Degnan, Andrew P
Published in ACS medicinal chemistry letters (10.03.2016)
Published in ACS medicinal chemistry letters (10.03.2016)
Get full text
Journal Article