A review of the ADAMTS family, pharmaceutical targets of the future
Tortorella, Micky D, Malfait, Fransiska, Barve, Ruteja A, Shieh, Huey-Sheng, Malfait, Anne-Marie
Published in Current pharmaceutical design (01.07.2009)
Published in Current pharmaceutical design (01.07.2009)
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Structural and Inhibition Analysis Reveals the Mechanism of Selectivity of a Series of Aggrecanase Inhibitors
Tortorella, Micky D., Tomasselli, Alfredo G., Mathis, Karl J., Schnute, Mark E., Woodard, Scott S., Munie, Grace, Williams, Jennifer M., Caspers, Nicole, Wittwer, Arthur J., Malfait, Anne-Marie, Shieh, Huey-Sheng
Published in The Journal of biological chemistry (04.09.2009)
Published in The Journal of biological chemistry (04.09.2009)
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High Resolution Crystal Structure of the Catalytic Domain of ADAMTS-5 (Aggrecanase-2)
Shieh, Huey-Sheng, Mathis, Karl J., Williams, Jennifer M., Hills, Robert L., Wiese, Joe F., Benson, Timothy E., Kiefer, James R., Marino, Margaret H., Carroll, Jeffery N., Leone, Joseph W., Malfait, Anne-Marie, Arner, Elizabeth C., Tortorella, Micky D., Tomasselli, Alfredo
Published in The Journal of biological chemistry (18.01.2008)
Published in The Journal of biological chemistry (18.01.2008)
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Structure analysis reveals the flexibility of the ADAMTS‐5 active site
Shieh, Huey‐Sheng, Tomasselli, Alfredo G., Mathis, Karl J., Schnute, Mark E., Woodard, Scott S., Caspers, Nicole, Williams, Jennifer M., Kiefer, James R., Munie, Grace, Wittwer, Arthur, Malfait, Anne‐Marie, Tortorella, Micky D.
Published in Protein science (01.04.2011)
Published in Protein science (01.04.2011)
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Synthesis, Crystal Structure, and Activity of Pyrazole-Based Inhibitors of p38 Kinase
Graneto, Matthew J, Kurumbail, Ravi G, Vazquez, Michael L, Shieh, Huey-Sheng, Pawlitz, Jennifer L, Williams, Jennifer M, Stallings, William C, Geng, Lifeng, Naraian, Ashok S, Koszyk, Francis J, Stealey, Michael A, Xu, Xiangdong D, Weier, Richard M, Hanson, Gunnar J, Mourey, Robert J, Compton, Robert P, Mnich, Stephen J, Anderson, Gary D, Monahan, Joseph B, Devraj, Rajesh
Published in Journal of medicinal chemistry (15.11.2007)
Published in Journal of medicinal chemistry (15.11.2007)
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Structure of human ADAM-8 catalytic domain complexed with batimastat
Hall, Troii, Shieh, Huey-Sheng, Day, Jacqueline E., Caspers, Nicole, Chrencik, Jill E., Williams, Jennifer M., Pegg, Lyle E., Pauley, Adele M., Moon, Andrea F., Krahn, Joseph M., Fischer, David H., Kiefer, James R., Tomasselli, Alfredo G., Zack, Marc D.
Published in Acta crystallographica. Section F, Structural biology and crystallization communications (01.06.2012)
Published in Acta crystallographica. Section F, Structural biology and crystallization communications (01.06.2012)
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An Active Site of Transforming Growth Factor-β1 for Growth Inhibition and Stimulation
Huang, Shuan Shian, Zhou, Mi, Johnson, Frank E., Shieh, Huey-Sheng, Huang, Jung San
Published in The Journal of biological chemistry (24.09.1999)
Published in The Journal of biological chemistry (24.09.1999)
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Structure and topological symmetry of the glyphosate target 5-enol-pyruvylshikimate-3-phosphate synthase: A distinctive protein fold
Stallings, W.C. (Monsanto Company, St. Louis, MO), Abdel-Meguid, S.S, Lim, L.W, Shieh, H.S, Dayringer, H.E, Leimgruber, N.K, Stegeman, R.A, Anderson, K.S, Sikorski, J.A, Padgette, S.R, Kishore, G.M
Published in Proceedings of the National Academy of Sciences - PNAS (01.06.1991)
Published in Proceedings of the National Academy of Sciences - PNAS (01.06.1991)
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Solution structure and backbone dynamics of the catalytic domain of matrix metalloproteinase-2 complexed with a hydroxamic acid inhibitor
Feng, Yiqing, Likos, John J, Zhu, Leiming, Woodward, Harold, Munie, Grace, McDonald, Joseph J, Stevens, Anna M, Howard, Carol P, De Crescenzo, Gary A, Welsch, Dean, Shieh, Huey-Sheng, Stallings, William C
Published in Biochimica et biophysica acta (29.07.2002)
Published in Biochimica et biophysica acta (29.07.2002)
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Inhibitors of HIV-1 Protease Containing the Novel and Potent (R)-(Hydroxyethyl)sulfonamide Isostere
Vazquez, Michael L, Bryant, Martin L, Clare, Michael, DeCrescenzo, Gary A, Doherty, Elizabeth M, Freskos, John N, Getman, Daniel P, Houseman, Kathryn A, Julien, Janet A, Kocan, Geralyn P, Mueller, Richard A, Shieh, Huey-Sheng, Stallings, William C, Stegeman, Roderick A, Tilley, John J
Published in Journal of medicinal chemistry (01.02.1995)
Published in Journal of medicinal chemistry (01.02.1995)
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Three-dimensional structure of human cytomegalovirus protease
Shieh, Huey-Sheng, Kurumbail, Ravi G, Stevens, Anna M, Stegeman, Roderick A, Sturman, Eric J, Pak, Jina Y, Wittwer, Arthur J, Palmier, Mark O, Wiegand, Roger C, Holwerda, Barry C, Stallings, William C
Published in Nature (London) (19.09.1996)
Published in Nature (London) (19.09.1996)
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Magnetic exchange interactions in nitroxyl biradicals bridged by metal-metal bonded complexes: structural, magnetochemical, and electronic spectral characterization of tetrakis(perfluorocarboxylato)dimetal(II) complexes of rhodium and molybdenum containing axially coordinated nitroxyl radicals
Felthouse, Timothy R, Dong, Teng Yuan, Hendrickson, David N, Shieh, Huey Sheng, Thompson, Michael R
Published in Journal of the American Chemical Society (01.12.1986)
Published in Journal of the American Chemical Society (01.12.1986)
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Discovery of a novel class of potent HIV-1 protease inhibitors containing the (R)-(hydroxyethyl)urea isostere
Getman, Daniel P, DeCrescenzo, Gary A, Heintz, Robert M, Reed, Kathryn L, Talley, John J, Bryant, Martin L, Clare, Michael, Houseman, Kathryn A, Marr, J. Joseph
Published in Journal of medicinal chemistry (1993)
Published in Journal of medicinal chemistry (1993)
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Synthesis and activity of selective MMP inhibitors with an aryl backbone
E. Barta, Thomas, P. Becker, Daniel, J. Bedell, Louis, A. De Crescenzo, Gary, J. McDonald, Joseph, E. Munie, Grace, Rao, Shashi, Shieh, Huey-Sheng, Stegeman, Roderick, M. Stevens, Anna, I. Villamil, Clara
Published in Bioorganic & medicinal chemistry letters (18.12.2000)
Published in Bioorganic & medicinal chemistry letters (18.12.2000)
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Aspects of anionic rhodium complexes. Ligand effects
Chan, Albert S.C., Shieh, Huey-Sheng, Hill, Jeffrey R.
Published in Journal of organometallic chemistry (01.01.1985)
Published in Journal of organometallic chemistry (01.01.1985)
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Synthesis and identification of conformationally constrained selective MMP inhibitors
Freskos, John N., McDonald, Joseph J., Mischke, Brent V., Mullins, Patrick B., Shieh, Huey-Sheng, Stegeman, Roderick A., Stevens, Anna M.
Published in Bioorganic & medicinal chemistry letters (05.07.1999)
Published in Bioorganic & medicinal chemistry letters (05.07.1999)
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Bis(nitroxyl) radical adducts of rhodium(II) and molybdenum(II) carboxylate dimers: magnetic exchange interactions propagated by metal-metal bonds
Dong, Teng Yuan, Hendrickson, David N, Felthouse, Timothy R, Shieh, Huey Sheng
Published in Journal of the American Chemical Society (01.09.1984)
Published in Journal of the American Chemical Society (01.09.1984)
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