One-Step Generation of Mice Carrying Reporter and Conditional Alleles by CRISPR/Cas-Mediated Genome Engineering
Yang, Hui, Wang, Haoyi, Shivalila, Chikdu S., Cheng, Albert W., Shi, Linyu, Jaenisch, Rudolf
Published in Cell (12.09.2013)
Published in Cell (12.09.2013)
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Ubiquitination of RIPK1 regulates its activation mediated by TNFR1 and TLRs signaling in distinct manners
Li, Xingyan, Zhang, Mengmeng, Huang, Xinyue, Liang, Wei, Li, Ganquan, Lu, Xiaojuan, Li, Yanxia, Pan, Heling, Shi, Linyu, Zhu, Hong, Qian, Lihui, Shan, Bing, Yuan, Junying
Published in Nature communications (11.12.2020)
Published in Nature communications (11.12.2020)
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Glia-to-Neuron Conversion by CRISPR-CasRx Alleviates Symptoms of Neurological Disease in Mice
Zhou, Haibo, Su, Jinlin, Hu, Xinde, Zhou, Changyang, Li, He, Chen, Zhaorong, Xiao, Qingquan, Wang, Bo, Wu, Wenyan, Sun, Yidi, Zhou, Yingsi, Tang, Cheng, Liu, Fei, Wang, Linhan, Feng, Canbin, Liu, Mingzhe, Li, Sanlan, Zhang, Yifeng, Xu, Huatai, Yao, Haishan, Shi, Linyu, Yang, Hui
Published in Cell (30.04.2020)
Published in Cell (30.04.2020)
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Regulation of RIPK1 activation by TAK1-mediated phosphorylation dictates apoptosis and necroptosis
Geng, Jiefei, Ito, Yasushi, Shi, Linyu, Amin, Palak, Chu, Jiachen, Ouchida, Amanda Tomie, Mookhtiar, Adnan Kasim, Zhao, Heng, Xu, Daichao, Shan, Bing, Najafov, Ayaz, Gao, Guangping, Akira, Shizuo, Yuan, Junying
Published in Nature communications (25.08.2017)
Published in Nature communications (25.08.2017)
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Multiplexed activation of endogenous genes by CRISPR-on, an RNA-guided transcriptional activator system
Cheng, Albert W, Wang, Haoyi, Yang, Hui, Shi, Linyu, Katz, Yarden, Theunissen, Thorold W, Rangarajan, Sudharshan, Shivalila, Chikdu S, Dadon, Daniel B, Jaenisch, Rudolf
Published in Cell research (01.10.2013)
Published in Cell research (01.10.2013)
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Homology-mediated end joining-based targeted integration using CRISPR/Cas9
Yao, Xuan, Wang, Xing, Hu, Xinde, Liu, Zhen, Liu, Junlai, Zhou, Haibo, Shen, Xiaowen, Wei, Yu, Huang, Zijian, Ying, Wenqin, Wang, Yan, Nie, Yan-Hong, Zhang, Chen-Chen, Li, Sanlan, Cheng, Leping, Wang, Qifang, Wu, Yan, Huang, Pengyu, Sun, Qiang, Shi, Linyu, Yang, Hui
Published in Cell research (01.06.2017)
Published in Cell research (01.06.2017)
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CRISPR/Cas9-mediated targeted chromosome elimination
Zuo, Erwei, Huo, Xiaona, Yao, Xuan, Hu, Xinde, Sun, Yidi, Yin, Jianhang, He, Bingbing, Wang, Xing, Shi, Linyu, Ping, Jie, Wei, Yu, Ying, Wenqin, Wei, Wei, Liu, Wenjia, Tang, Cheng, Li, Yixue, Hu, Jiazhi, Yang, Hui
Published in Genome Biology (24.11.2017)
Published in Genome Biology (24.11.2017)
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Systematic Identification of Culture Conditions for Induction and Maintenance of Naive Human Pluripotency
Theunissen, Thorold W., Powell, Benjamin E., Wang, Haoyi, Mitalipova, Maya, Faddah, Dina A., Reddy, Jessica, Fan, Zi Peng, Maetzel, Dorothea, Ganz, Kibibi, Shi, Linyu, Lungjangwa, Tenzin, Imsoonthornruksa, Sumeth, Stelzer, Yonatan, Rangarajan, Sudharshan, D’Alessio, Ana, Zhang, Jianming, Gao, Qing, Dawlaty, Meelad M., Young, Richard A., Gray, Nathanael S., Jaenisch, Rudolf
Published in Cell stem cell (02.10.2014)
Published in Cell stem cell (02.10.2014)
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Tild-CRISPR Allows for Efficient and Precise Gene Knockin in Mouse and Human Cells
Yao, Xuan, Zhang, Meiling, Wang, Xing, Ying, Wenqin, Hu, Xinde, Dai, Pengfei, Meng, Feilong, Shi, Linyu, Sun, Yun, Yao, Ning, Zhong, Wanxia, Li, Yun, Wu, Keliang, Li, Weiping, Chen, Zi-jiang, Yang, Hui
Published in Developmental cell (21.05.2018)
Published in Developmental cell (21.05.2018)
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In vivo simultaneous transcriptional activation of multiple genes in the brain using CRISPR–dCas9-activator transgenic mice
Zhou, Haibo, Liu, Junlai, Zhou, Changyang, Gao, Ni, Rao, Zhiping, Li, He, Hu, Xinde, Li, Changlin, Yao, Xuan, Shen, Xiaowen, Sun, Yidi, Wei, Yu, Liu, Fei, Ying, Wenqin, Zhang, Junming, Tang, Cheng, Zhang, Xu, Xu, Huatai, Shi, Linyu, Cheng, Leping, Huang, Pengyu, Yang, Hui
Published in Nature neuroscience (01.03.2018)
Published in Nature neuroscience (01.03.2018)
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Engineered CRISPR-OsCas12f1 and RhCas12f1 with robust activities and expanded target range for genome editing
Kong, Xiangfeng, Zhang, Hainan, Li, Guoling, Wang, Zikang, Kong, Xuqiang, Wang, Lecong, Xue, Mingxing, Zhang, Weihong, Wang, Yao, Lin, Jiajia, Zhou, Jingxing, Shen, Xiaowen, Wei, Yinghui, Zhong, Na, Bai, Weiya, Yuan, Yuan, Shi, Linyu, Zhou, Yingsi, Yang, Hui
Published in Nature communications (11.04.2023)
Published in Nature communications (11.04.2023)
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One-step generation of complete gene knockout mice and monkeys by CRISPR/Cas9-mediated gene editing with multiple sgRNAs
Zuo, Erwei, Cai, Yi-Jun, Li, Kui, Wei, Yu, Wang, Bang-An, Sun, Yidi, Liu, Zhen, Liu, Jiwei, Hu, Xinde, Wei, Wei, Huo, Xiaona, Shi, Linyu, Tang, Cheng, Liang, Dan, Wang, Yan, Nie, Yan-Hong, Zhang, Chen-Chen, Yao, Xuan, Wang, Xing, Zhou, Changyang, Ying, Wenqin, Wang, Qifang, Chen, Ren-Chao, Shen, Qi, Xu, Guo-Liang, Li, Jinsong, Sun, Qiang, Xiong, Zhi-Qi, Yang, Hui
Published in Cell research (01.07.2017)
Published in Cell research (01.07.2017)
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Phosphorylation and activation of ubiquitin-specific protease-14 by Akt regulates the ubiquitin-proteasome system
Xu, Daichao, Shan, Bing, Lee, Byung-Hoon, Zhu, Kezhou, Zhang, Tao, Sun, Huawang, Liu, Min, Shi, Linyu, Liang, Wei, Qian, Lihui, Xiao, Juan, Wang, Lili, Pan, Lifeng, Finley, Daniel, Yuan, Junying
Published in eLife (02.11.2015)
Published in eLife (02.11.2015)
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Generation of haploid embryonic stem cells from Macaca fascicularis monkey parthenotes
Yang, Hui, Liu, Zhen, Ma, Yu, Zhong, Cuiqing, Yin, Qi, Zhou, Chikai, Shi, Linyu, Cai, Yijun, Zhao, Hanzhi, Wang, Hui, Tang, Fan, Wang, Yan, Zhang, Chenchen, Liu, Xin-yuan, Lai, Dongmei, Jin, Ying, Sun, Qiang, Li, Jinsong
Published in Cell research (01.10.2013)
Published in Cell research (01.10.2013)
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Mini-dCas13X-mediated RNA editing restores dystrophin expression in a humanized mouse model of Duchenne muscular dystrophy
Li, Guoling, Jin, Ming, Li, Zhifang, Xiao, Qingquan, Lin, Jiajia, Yang, Dong, Liu, Yuanhua, Wang, Xing, Xie, Long, Ying, Wenqin, Wang, Haoqiang, Zuo, Erwei, Shi, Linyu, Wang, Ning, Chen, Wanjin, Xu, Chunlong, Yang, Hui
Published in The Journal of clinical investigation (01.02.2023)
Published in The Journal of clinical investigation (01.02.2023)
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Development and validation of a multiplex 19 X-chromosomal short tandem repeats typing system for forensic purposes
Jia, Juan, Liu, Xu, Fan, Qingwei, Fang, Chen, Wang, Mengchun, Zhang, Jiarong, Li, Wanting, Shi, Linyu, Zhang, Xiaomeng, Chen, Chuguang, Yu, Zailiang, Li, Chen, Yun, Keming, Yan, Jiangwei
Published in Scientific reports (12.01.2021)
Published in Scientific reports (12.01.2021)
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Development of deaminase-free T-to-S base editor and C-to-G base editor by engineered human uracil DNA glycosylase
Tong, Huawei, Wang, Haoqiang, Wang, Xuchen, Liu, Nana, Li, Guoling, Wu, Danni, Li, Yun, Jin, Ming, Li, Hengbin, Wei, Yinghui, Li, Tong, Yuan, Yuan, Shi, Linyu, Yao, Xuan, Zhou, Yingsi, Yang, Hui
Published in Nature communications (08.06.2024)
Published in Nature communications (08.06.2024)
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Journal Article
Precise genome editing without exogenous donor DNA via retron editing system in human cells
Kong, Xiangfeng, Wang, Zikang, Zhang, Renxia, Wang, Xing, Zhou, Yingsi, Shi, Linyu, Yang, Hui
Published in Protein & cell (01.11.2021)
Published in Protein & cell (01.11.2021)
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