Discovery of Pyrido[2,3‑b]indole Derivatives with Gram-Negative Activity Targeting Both DNA Gyrase and Topoisomerase IV
Hu, Yimin, Shi, Houguang, Zhou, Mingwei, Ren, Qingcheng, Zhu, Wei, Zhang, Weixing, Zhang, Zhiwei, Zhou, Chengang, Liu, Yongqiang, Ding, Xiao, Shen, Hong C, Yan, S. Frank, Dey, Fabian, Wu, Waikwong, Zhai, Guanglei, Zhou, Zheng, Xu, Zhiheng, Ji, Ying, Lv, Hua, Jiang, Tianyi, Wang, Wen, Xu, Yunhua, Vercruysse, Maarten, Yao, Xiangyu, Mao, Yi, Yu, Xiaomin, Bradley, Kenneth, Tan, Xuefei
Published in Journal of medicinal chemistry (10.09.2020)
Published in Journal of medicinal chemistry (10.09.2020)
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Discovery of Linvencorvir (RG7907), a Hepatitis B Virus Core Protein Allosteric Modulator, for the Treatment of Chronic HBV Infection
Zhang, Weixing, Guo, Lei, Liu, Haixia, Wu, Guolong, Shi, Houguang, Zhou, Mingwei, Zhang, Zhisen, Kou, Buyu, Hu, Taishan, Zhou, Zheng, Xu, Zhiheng, Zhou, Xue, Zhou, Yuan, Tian, Xiaojun, Yang, Guang, Young, John A. T., Qiu, Hongxia, Ottaviani, Giorgio, Xie, Jianxun, Mayweg, Alexander V., Shen, Hong C., Zhu, Wei
Published in Journal of medicinal chemistry (23.03.2023)
Published in Journal of medicinal chemistry (23.03.2023)
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From α-keto acids to nitrile oxides enabled by copper nitrate: a facile access to fused isoxazolines
Zhu, Yuping, Liu, Tianqi, Liu, Bingxin, Shi, Houguang, Tan, Qitao, Xu, Bin
Published in Organic chemistry frontiers an international journal of organic chemistry (01.02.2022)
Published in Organic chemistry frontiers an international journal of organic chemistry (01.02.2022)
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Journal Article
A New Approach of Mitigating CYP3A4 Induction Led to the Discovery of Potent Hepatitis B Virus (HBV) Capsid Inhibitor with Optimal ADMET Profiles
Lin, Xianfeng, Shi, Houguang, Zhang, Weixing, Qiu, Zongxing, Zhou, Zheng, Dey, Fabian, Zhong, Sheng, Qiu, Hongxia, Xie, Jianxun, Zhou, Xue, Yang, Guang, Tang, Guozhi, Shen, Hong C, Zhu, Wei
Published in Journal of medicinal chemistry (27.11.2019)
Published in Journal of medicinal chemistry (27.11.2019)
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Discovery and Pre-Clinical Characterization of Third-Generation 4‑H Heteroaryldihydropyrimidine (HAP) Analogues as Hepatitis B Virus (HBV) Capsid Inhibitors
Qiu, Zongxing, Lin, Xianfeng, Zhang, Weixing, Zhou, Mingwei, Guo, Lei, Kocer, Buelent, Wu, Guolong, Zhang, Zhisen, Liu, Haixia, Shi, Houguang, Kou, Buyu, Hu, Taishan, Hu, Yimin, Huang, Mengwei, Yan, S. Frank, Xu, Zhiheng, Zhou, Zheng, Qin, Ning, Wang, Yue Fen, Ren, Shuang, Qiu, Hongxia, Zhang, Yuxia, Zhang, Yi, Wu, Xiaoyue, Sun, Kai, Zhong, Sheng, Xie, Jianxun, Ottaviani, Giorgio, Zhou, Yuan, Zhu, Lina, Tian, Xiaojun, Shi, Liping, Shen, Fang, Mao, Yi, Zhou, Xue, Gao, Lu, Young, John A. T, Wu, Jim Zhen, Yang, Guang, Mayweg, Alexander V, Shen, Hong C, Tang, Guozhi, Zhu, Wei
Published in Journal of medicinal chemistry (27.04.2017)
Published in Journal of medicinal chemistry (27.04.2017)
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Journal Article
B 6- NOVEL 6-FUSED HETEROARYLDIHYDROPYRIMIDINES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION
ZHANG ZHISEN, ZHOU MINGWEI, ZHU WEI, SHI HOUGUANG, GUO LEI, KOU BUYU, YAN SHIXIANG, LIN XIANFENG, ZHANG WEIXING, SHEN HONG, HU TAISHAN
Year of Publication 05.12.2018
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Year of Publication 05.12.2018
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NOVEL 6-FUSED HETEROARYLDIHYDROPYRIMIDINES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION
ZHANG ZHISEN, ZHOU MINGWEI, ZHU WEI, SHI HOUGUANG, GUO LEI, KOU BUYU, YAN SHIXIANG, LIN XIANFENG, ZHANG WEIXING, SHEN HONG, HU TAISHAN
Year of Publication 08.09.2016
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Year of Publication 08.09.2016
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6-BRIDGED HETEROARYLDIHYDROPYRIMIDINES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION
KOCER BUELENT, ZHANG ZHISEN, ZHOU MINGWEI, SHI HOUGUANG, LIN XIANFENG, SHEN HONG, HU YIMIN, LI GANGQIN, ZHU WEI, GUO LEI, LIU HAIXIA, KOU BUYU, HU TAISHAN, WU GUOLONG
Year of Publication 26.01.2016
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Year of Publication 26.01.2016
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TRICYCLIC COMPOUNDS FOR TREATMENT OF BACTERIAL INFECTIONS
WU, Jun, DEY, Fabian, LERNER, Christian, DING, Xiao, SHI, Houguang, ZHENG, Jiamin, TAN, Xuefei
Year of Publication 17.10.2024
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Year of Publication 17.10.2024
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Year of Publication 02.10.2024
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Year of Publication 07.09.2023
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Year of Publication 07.09.2023
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SUBSTITUTED PYRIDOINDOLES FOR THE TREATMENT AND PROPHYLAXIS OF BACTERIAL INFECTION
SHEN, Hong, ZHOU, Mingwei, DING, Xiao, LIU, Yongqiang, SHI, Houguang, ZHOU, Chengang, TAN, Xuefei
Year of Publication 19.07.2023
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Year of Publication 19.07.2023
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SHEN, Hong, ZHOU, Mingwei, DING, Xiao, LIU, Yongqiang, SHI, Houguang, ZHOU, Chengang, TAN, Xuefei
Year of Publication 19.07.2023
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WU, Jun, ZHOU, Mingwei, DEY, Fabian, DING, Xiao, SHI, Houguang, ZHENG, Jiamin, TAN, Xuefei
Year of Publication 04.05.2023
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Year of Publication 04.05.2023
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Year of Publication 17.10.2024
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Year of Publication 17.10.2024
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WU, Jun, ZHOU, Mingwei, DEY, Fabian, AMREIN, Kurt, LERNER, Christian, DING, Xiao, SHI, Houguang, ZHENG, Jiamin, HUANG, Xinyi, TAN, Xuefei
Year of Publication 21.08.2024
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Year of Publication 21.08.2024
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SHEN, Hong, ZHOU, Mingwei, DEY, Fabian, HU, Yimin, DING, Xiao, LIU, Yongqiang, SHI, Houguang, ZHOU, Chengang, TAN, Xuefei
Year of Publication 01.03.2023
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Year of Publication 01.03.2023
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SUBSTITUTED PYRIDOINDOLES FOR THE TREATMENT AND PROPHYLAXIS OF BACTERIAL INFECTION
SHEN, Hong, ZHOU, Mingwei, DING, Xiao, LIU, Yongqiang, SHI, Houguang, ZHOU, Chengang, TAN, Xuefei
Year of Publication 04.08.2021
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Year of Publication 04.08.2021
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SUBSTITUTED PYRIDOINDOLES FOR THE TREATMENT AND PROPHYLAXIS OF BACTERIAL INFECTION
SHEN, Hong, ZHOU, Mingwei, DING, Xiao, LIU, Yongqiang, SHI, Houguang, ZHOU, Chengang, TAN, Xuefei
Year of Publication 22.07.2021
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Year of Publication 22.07.2021
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