Translation of 11C-labeled tracer synthesis to a CGMP environment as exemplified by [11C]ER176 for PET imaging of human TSPO
Hong, Jinsoo, Telu, Sanjay, Zhang, Yi, Miller, William H., Shetty, H. Umesha, Morse, Cheryl L., Pike, Victor W.
Published in Nature protocols (01.09.2021)
Published in Nature protocols (01.09.2021)
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Journal Article
Radiodefluorination of 3-Fluoro-5-(2-(2-[18F](fluoromethyl)-thiazol-4-yl)ethynyl)benzonitrile ([18F]SP203), a Radioligand for Imaging Brain Metabotropic Glutamate Subtype-5 Receptors with Positron Emission Tomography, Occurs by Glutathionylation in Rat Brain
Shetty, H Umesha, Zoghbi, Sami S, Siméon, Fabrice G, Liow, Jeih-San, Brown, Amira K, Kannan, Pavitra, Innis, Robert B, Pike, Victor W
Published in The Journal of pharmacology and experimental therapeutics (01.12.2008)
Published in The Journal of pharmacology and experimental therapeutics (01.12.2008)
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Journal Article
Effects of ketoconazole on the biodistribution and metabolism of [11 C]loperamide and [11 C] N -desmethyl-loperamide in wild-type and P-gp knockout mice
Seneca, Nicholas, Zoghbi, Sami S, Shetty, H. Umesha, Tuan, Edward, Kannan, Pavitra, Taku, Andrew, Innis, Robert B, Pike, Victor W
Published in Nuclear medicine and biology (01.04.2010)
Published in Nuclear medicine and biology (01.04.2010)
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Journal Article
Identification and regional distribution in rat brain of radiometabolites of the dopamine transporter PET radioligand [11C]PE2I
Shetty, H Umesha, Zoghbi, Sami S, Liow, Jeih-San, Ichise, Masanori, Hong, Jinsoo, Musachio, John L, Halldin, Christer, Seidel, Jurgen, Innis, Robert B, Pike, Victor W
Published in European journal of nuclear medicine and molecular imaging (01.05.2007)
Published in European journal of nuclear medicine and molecular imaging (01.05.2007)
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Journal Article
Whole-Body PET Imaging in Humans Shows That 11C-PS13 Is Selective for Cyclooxygenase-1 and Can Measure the In Vivo Potency of Nonsteroidal Antiinflammatory Drugs
Kim, Min-Jeong, Anaya, Fernanda Juarez, Manly, Lester S, Lee, Jae-Hoon, Hong, Jinsoo, Shrestha, Stal, Telu, Sanjay, Henry, Katharine, Montero Santamaria, Jose A, Liow, Jeih-San, Zanotti-Fregonara, Paolo, Shetty, H Umesha, Zoghbi, Sami S, Pike, Victor W, Innis, Robert B
Published in The Journal of nuclear medicine (1978) (01.01.2023)
Published in The Journal of nuclear medicine (1978) (01.01.2023)
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Journal Article
Whole-Body PET Imaging in Humans Shows That 11 C-PS13 Is Selective for Cyclooxygenase-1 and Can Measure the In Vivo Potency of Nonsteroidal Antiinflammatory Drugs
Kim, Min-Jeong, Anaya, Fernanda Juarez, Manly, Lester S, Lee, Jae-Hoon, Hong, Jinsoo, Shrestha, Stal, Telu, Sanjay, Henry, Katharine, Santamaria, Jose A Montero, Liow, Jeih-San, Zanotti-Fregonara, Paolo, Shetty, H Umesha, Zoghbi, Sami S, Pike, Victor W, Innis, Robert B
Published in Journal of Nuclear Medicine (01.01.2023)
Published in Journal of Nuclear Medicine (01.01.2023)
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Journal Article
Increased permeability-glycoprotein inhibition at the human blood-brain barrier can be safely achieved by performing PET during peak plasma concentrations of tariquidar
Kreisl, William C, Bhatia, Ritwik, Morse, Cheryl L, Woock, Alicia E, Zoghbi, Sami S, Shetty, H Umesha, Pike, Victor W, Innis, Robert B
Published in Journal of Nuclear Medicine (01.01.2015)
Published in Journal of Nuclear Medicine (01.01.2015)
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Journal Article
Development of a non-radiometric method for measuring the arterial input function of a 11C-labeled PET radiotracer
Shetty, H. Umesha, Zoghbi, Sami S., Morse, Cheryl L., Kowalski, Aneta, Hirvonen, Jussi, Innis, Robert B., Pike, Victor W.
Published in Scientific reports (15.10.2020)
Published in Scientific reports (15.10.2020)
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Journal Article
Single-Step High-Yield Radiosynthesis and Evaluation of a Sensitive 18F-Labeled Ligand for Imaging Brain Peripheral Benzodiazepine Receptors with PET
Briard, Emmanuelle, Zoghbi, Sami S, Siméon, Fabrice G, Imaizumi, Masao, Gourley, Jonathan P, Shetty, H. Umesha, Lu, Shuiyu, Fujita, Masahiro, Innis, Robert B, Pike, Victor W
Published in Journal of medicinal chemistry (12.02.2009)
Published in Journal of medicinal chemistry (12.02.2009)
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Journal Article
Synthesis and Evaluation in Monkey of Two Sensitive 11C-Labeled Aryloxyanilide Ligands for Imaging Brain Peripheral Benzodiazepine Receptors In Vivo
Briard, Emmanuelle, Zoghbi, Sami S, Imaizumi, Masao, Gourley, Jonathan P, Shetty, H. Umesha, Hong, Jinsoo, Cropley, Vanessa, Fujita, Masahiro, Innis, Robert B, Pike, Victor W
Published in Journal of medicinal chemistry (10.01.2008)
Published in Journal of medicinal chemistry (10.01.2008)
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Journal Article
(18)F-FCWAY, a serotonin 1A receptor radioligand, is a substrate for efflux transport at the human blood-brain barrier
Liow, Jeih-San, Zoghbi, Sami S, Hu, Shuo, Hall, Matthew D, Hines, Christina S, Shetty, H Umesha, Araneta, Maria D, Page, Emily M, Pike, Victor W, Kreisl, William C, Herscovitch, Peter, Gottesman, Michael M, Theodore, William H, Innis, Robert B
Published in NeuroImage (Orlando, Fla.) (01.09.2016)
Published in NeuroImage (Orlando, Fla.) (01.09.2016)
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Journal Article
18F-FCWAY, a serotonin 1A receptor radioligand, is a substrate for efflux transport at the human blood-brain barrier
Liow, Jeih-San, Zoghbi, Sami S., Hu, Shuo, Hall, Matthew D., Hines, Christina S., Shetty, H. Umesha, Araneta, Maria D., Page, Emily M., Pike, Victor W., Kreisl, William C., Herscovitch, Peter, Gottesman, Michael M., Theodore, William H., Innis, Robert B.
Published in NeuroImage (Orlando, Fla.) (01.09.2016)
Published in NeuroImage (Orlando, Fla.) (01.09.2016)
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Journal Article
Free radical metabolism of raloxifene in human liver microsomes
Lim, Heng-Keang, Yang, Min, Lam, Wing, Xu, Fran, Chen, Jie, Xu, Yaodong, Shetty, H. Umesha, Yang, Ke, Silva, Jose, Evans, David C.
Published in Xenobiotica (01.08.2012)
Published in Xenobiotica (01.08.2012)
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Journal Article
Comparison of human plasma arterial input function for [11C]MePPEP determined with LC-MS/MS and radiometric methods
Pike, Victor W., Zoghbi, Sami S., Shetty, H. Umesha, Hirvonen, Jussi, Anderson, Kacey B., Jenko, Kimberly J., Morse, Cheryl, Innis, Robert B.
Published in NeuroImage (Orlando, Fla.) (01.08.2010)
Published in NeuroImage (Orlando, Fla.) (01.08.2010)
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Journal Article
Phospholipid composition and levels are altered in down syndrome brain
Murphy, Eric J., Schapiro, Mark B., Rapoport, Stanley I., Shetty, H.Umesha
Published in Brain research (09.06.2000)
Published in Brain research (09.06.2000)
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Journal Article
Synthesis and initial evaluation of [11C](R)-RWAY in monkey-a new, simply labeled antagonist radioligand for imaging brain 5-HT1A receptors with PET
McCarron, Julie A, Zoghbi, Sami S, Shetty, H Umesha, Vermeulen, Eric S, Wikström, Håkan V, Ichise, Masanori, Yasuno, Fumihiko, Halldin, Christer, Innis, Robert B, Pike, Victor W
Published in European journal of nuclear medicine and molecular imaging (01.10.2007)
Published in European journal of nuclear medicine and molecular imaging (01.10.2007)
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Journal Article
Investigation of the Metabolites of (S,S)-[11C]MeNER in Humans, Monkeys and Rats
Schou, Magnus, Zoghbi, Sami S., Shetty, H. Umesha, Shchukin, Evgeny, Liow, Jeih-San, Hong, Jinsoo, Andrée, Bengt A., Gulyás, Balázs, Farde, Lars, Innis, Robert B., Pike, Victor W., Halldin, Christer
Published in Molecular imaging and biology (01.01.2009)
Published in Molecular imaging and biology (01.01.2009)
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Journal Article