Use of a glutaric acid cocrystal to improve oral bioavailability of a low solubility API
MCNAMARA, Daniel P, CHILDS, Scott L, GIORDANO, Jennifer, IARRICCIO, Anthony, CASSIDY, James, SHET, Manjunath S, MANNION, Richard, O'DONNELL, Ed, PARK, Aeri
Published in Pharmaceutical research (01.08.2006)
Published in Pharmaceutical research (01.08.2006)
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Once-Weekly Transdermal Buprenorphine Application Results in Sustained and Consistent Steady-State Plasma Levels
Kapil, Ram P., PhD, Cipriano, Alessandra, BS, Friedman, Kristen, MPH, Michels, Gregory, MS, Shet, Manjunath S., PhD, Colucci, Salvatore V., MS, Apseloff, Glen, MD, FCP, Kitzmiller, Joseph, MD, PhD, CPI, Harris, Stephen C., MD
Published in Journal of pain and symptom management (01.07.2013)
Published in Journal of pain and symptom management (01.07.2013)
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Development and validation of a sensitive LC/MS/MS method for the simultaneous determination of naloxone and its metabolites in mouse plasma
Jiang, Hongliang, Wang, YuRong, Shet, Manjunath S., Zhang, Yang, Zenke, Duane, Fast, Douglas M.
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01.09.2011)
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01.09.2011)
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Journal Article
The nociceptin/orphanin FQ receptor partial agonist sunobinop promotes non-REM sleep in rodents and patients with insomnia
Whiteside, Garth T, Kyle, Donald J, Kapil, Ram R, Cipriano, Alessandra, He, Ellie, Zhou, Mingyan, Shet, Manjunath S, Hummel, Michele, Knappenberger, Terri, Fukumura, Kazuya, Matsuo, Yoshiyuki, Uehira, Masahiro, Hiroyama, Shuichi, Takai, Nozomi, Willsie, Sandra K, Harris, Stephen C
Published in The Journal of clinical investigation (02.01.2024)
Published in The Journal of clinical investigation (02.01.2024)
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Journal Article
The nociceptin/orphanin FQ receptor partial agonist sunobinop promotes non-REM sleep in rodents and patients with insomnia
Whiteside, Garth T, Kyle, Donald J, Kapil, Ram P, Cipriano, Alessandra, He, Ellie, Zhou, Mingyan, Shet, Manjunath S, Hummel, Michele, Knappenberger, Terri, Fukumura, Kazuya, Matsuo, Yoshiyuki, Uehira, Masahiro, Hiroyama, Shuichi, Takai, Nozomi, Willsie, Sandra K, Harris, Stephen C
Published in The Journal of clinical investigation (01.01.2024)
Published in The Journal of clinical investigation (01.01.2024)
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Particulate levodopa nose-to-brain delivery targets dopamine to the brain with no plasma exposure
Dimiou, Savvas, Lopes, Rui M., Kubajewska, Ilona, Mellor, Ryan D., Schlosser, Corinna S., Shet, Manjunath S., Huang, Hugh, Akcan, Ozgur, Whiteside, Garth T., Schätzlein, Andreas G., Uchegbu, Ijeoma F.
Published in International journal of pharmaceutics (25.04.2022)
Published in International journal of pharmaceutics (25.04.2022)
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Safety, Tolerability, and Pharmacokinetics of Single‐ and Multiple‐Ascending Doses of Sunobinop in Healthy Participants
Cipriano, Alessandra, Kapil, Ram P., Zhou, Mingyan, Shet, Manjunath S., Whiteside, Garth T., Willsie, Sandra K., Harris, Stephen C.
Published in Clinical pharmacology in drug development (01.07.2024)
Published in Clinical pharmacology in drug development (01.07.2024)
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Journal Article
Effect of Ketoconazole on the Pharmacokinetic Profile of Buprenorphine following Administration of a Once-Weekly Buprenorphine Transdermal System
Kapil, Ram P., Cipriano, Alessandra, Michels, Gregory H., Perrino, Peter, OʼKeefe, Sarah A., Shet, Manjunath S., Colucci, Salvatore V., Noveck, Robert J., Harris, Stephen C.
Published in Clinical drug investigation (01.09.2012)
Published in Clinical drug investigation (01.09.2012)
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Journal Article
Effect of Ketoconazole on the Pharmacokinetic Profile of Buprenorphine following Administration of a Once-Weekly Buprenorphine Transdermal System
Kapil, Ram P., Cipriano, Alessandra, Michels, Gregory H., Perrino, Peter, O’Keefe, Sarah A., Shet, Manjunath S., Colucci, Salvatore V., Noveck, Robert J., Harris, Stephen C.
Published in Clinical drug investigation (01.09.2012)
Published in Clinical drug investigation (01.09.2012)
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Comparison of the 17α-Hydroxylase C17,20-Lyase Activities of Porcine, Guinea Pig and Bovine P450c17 Using Purified Recombinant Fusion Proteins Containing P450c17 Linked to NADPH-P450 Reductase
Shet, Manjunath S., Fisher, Charles W., Tremblay, Yves, Belanger, Alain, Conley, Alan J., Ian Mason, J., Estabrook, Ronald W.
Published in Drug metabolism reviews (01.01.2007)
Published in Drug metabolism reviews (01.01.2007)
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Metabolism of the Antiandrogenic Drug (Flutamide) by Human CYP1A2
SHET, M. S, MCPHAUL, M, FISHER, C. W, STALLINGS, N. R, ESTABROOK, R. W
Published in Drug metabolism and disposition (01.11.1997)
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Published in Drug metabolism and disposition (01.11.1997)
Journal Article
Human Cytochrome P450 3A4: Enzymatic Properties of a Purified Recombinant Fusion Protein Containing NADPH-P450 Reductase
Shet, Manjunath S., Fisher, Charles W., Holmans, Priscilla L., Estabrook, Ronald W.
Published in Proceedings of the National Academy of Sciences - PNAS (15.12.1993)
Published in Proceedings of the National Academy of Sciences - PNAS (15.12.1993)
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High-Level Expression in Escherichia coli of Enzymatically Active Fusion Proteins Containing the Domains of Mammalian Cytochromes P450 and NADPH- P450 Reductase Flavoprotein
Fisher, Charles W., Shet, Manjunath S., Caudle, Deborah L., Martin-Wixtrom, Cheryl A., Estabrook, Ronald W.
Published in Proceedings of the National Academy of Sciences - PNAS (15.11.1992)
Published in Proceedings of the National Academy of Sciences - PNAS (15.11.1992)
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The Omega-Hydroxylation of Lauric Acid: Oxidation of 12-Hydroxylauric Acid to Dodecanedioic Acid by a Purified Recombinant Fusion Protein Containing P450 4A1 and NADPH–P450 Reductase
Shet, Manjunath S., Fisher, Charles W., Holmans, Priscila L., Estabrook, Ronald W.
Published in Archives of biochemistry and biophysics (01.06.1996)
Published in Archives of biochemistry and biophysics (01.06.1996)
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