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Meng, Wei, Ellsworth, Bruce A, Nirschl, Alexandra A, McCann, Peggy J, Patel, Manorama, Girotra, Ravindar N, Wu, Gang, Sher, Philip M, Morrison, Eamonn P, Biller, Scott A, Zahler, Robert, Deshpande, Prashant P, Pullockaran, Annie, Hagan, Deborah L, Morgan, Nathan, Taylor, Joseph R, Obermeier, Mary T, Humphreys, William G, Khanna, Ashish, Discenza, Lorell, Robertson, James G, Wang, Aiying, Han, Songping, Wetterau, John R, Janovitz, Evan B, Flint, Oliver P, Whaley, Jean M, Washburn, William N
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Published in Journal of medicinal chemistry (13.03.2008)
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Utilization of an Active Site Mutant Receptor for the Identification of Potent and Selective Atypical 5‑HT2C Receptor Agonists
Carpenter, Joseph, Wang, Ying, Wu, Gang, Feng, Jianxin, Ye, Xiang-Yang, Morales, Christian L, Broekema, Matthias, Rossi, Karen A, Miller, Keith J, Murphy, Brian J, Wu, Ginger, Malmstrom, Sarah E, Azzara, Anthony V, Sher, Philip M, Fevig, John M, Alt, Andrew, Bertekap, Robert L, Cullen, Mary Jane, Harper, Timothy M, Foster, Kimberly, Luk, Emily, Xiang, Qian, Grubb, Mary F, Robl, Jeffrey A, Wacker, Dean A
Published in Journal of medicinal chemistry (27.07.2017)
Published in Journal of medicinal chemistry (27.07.2017)
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Journal Article
Utilization of an Active Site Mutant Receptor for the Identification of Potent and Selective Atypical 5-HT 2C Receptor Agonists
Carpenter, Joseph, Wang, Ying, Wu, Gang, Feng, Jianxin, Ye, Xiang-Yang, Morales, Christian L, Broekema, Matthias, Rossi, Karen A, Miller, Keith J, Murphy, Brian J, Wu, Ginger, Malmstrom, Sarah E, Azzara, Anthony V, Sher, Philip M, Fevig, John M, Alt, Andrew, Bertekap, Jr, Robert L, Cullen, Mary Jane, Harper, Timothy M, Foster, Kimberly, Luk, Emily, Xiang, Qian, Grubb, Mary F, Robl, Jeffrey A, Wacker, Dean A
Published in Journal of medicinal chemistry (27.07.2017)
Published in Journal of medicinal chemistry (27.07.2017)
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Aglycone exploration of C-arylglucoside inhibitors of renal sodium-dependent glucose transporter SGLT2
Ellsworth, Bruce A., Meng, Wei, Patel, Manorama, Girotra, Ravindar N., Wu, Gang, Sher, Philip M., Hagan, Deborah L., Obermeier, Mary T., Humphreys, William G., Robertson, James G., Wang, Aiying, Han, Songping, Waldron, Thomas L., Morgan, Nathan N., Whaley, Jean M., Washburn, William N.
Published in Bioorganic & medicinal chemistry letters (01.09.2008)
Published in Bioorganic & medicinal chemistry letters (01.09.2008)
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Reductions in log P Improved Protein Binding and Clearance Predictions Enabling the Prospective Design of Cannabinoid Receptor (CB1) Antagonists with Desired Pharmacokinetic Properties
Ellsworth, Bruce A, Sher, Philip M, Wu, Ximao, Wu, Gang, Sulsky, Richard B, Gu, Zhengxiang, Murugesan, Natesan, Zhu, Yeheng, Yu, Guixue, Sitkoff, Doree F, Carlson, Kenneth E, Kang, Liya, Yang, Yifan, Lee, Ning, Baska, Rose A, Keim, William J, Cullen, Mary Jane, Azzara, Anthony V, Zuvich, Eva, Thomas, Michael A, Rohrbach, Kenneth W, Devenny, James J, Godonis, Helen E, Harvey, Susan J, Murphy, Brian J, Everlof, Gerry G, Stetsko, Paul I, Gudmundsson, Olafur, Johnghar, Susan, Ranasinghe, Asoka, Behnia, Kamelia, Pelleymounter, Mary Ann, Ewing, William R
Published in Journal of medicinal chemistry (12.12.2013)
Published in Journal of medicinal chemistry (12.12.2013)
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Carboxyl-promoted enhancement of selectivity for the β3 adrenergic receptor. Negative charge of the sulfonic acid BMS-187413 introduces β3 binding selectivity
SHER, P. M, MATHUR, A, FISHER, L. G, WU, G, SKWISH, S, MICHEL, I. M, SEILER, S. M, DICKINSON, K. E. J
Published in Bioorganic & medicinal chemistry letters (01.06.1997)
Published in Bioorganic & medicinal chemistry letters (01.06.1997)
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Interphenylene 7-oxabicyclo[2.2.1]heptane oxazoles. Highly potent, selective, and long-acting thromboxane A2 receptor antagonists
Misra, Raj N, Brown, Baerbel R, Sher, Philip M, Patel, Manorama M, Hall, Steven E, Han, Wen Ching, Barrish, Joel C, Kocy, Octavian, Harris, Don N
Published in Journal of medicinal chemistry (01.05.1993)
Published in Journal of medicinal chemistry (01.05.1993)
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Addition of Benzylic and Allylic Organozinc and Grignard Reagents to Resin-Bound Imines To Provide α-Branched Secondary Amines Bearing a Wide Variety of Functional Groups. Utility in the Synthesis of β-3 Adrenergic Receptor Agonists
Wu, Gang, Cai, Zhen-Wei, Bednarz, Mark S, Kocy, Octavian R, Gavai, Ashvinikumar V, Godfrey, Jollie D, Washburn, William N, Poss, Michael A, Sher, Philip M
Published in Journal of combinatorial chemistry (01.01.2005)
Published in Journal of combinatorial chemistry (01.01.2005)
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LU92182I
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Year of Publication 04.01.2019
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Year of Publication 04.01.2019
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compostos intermediários para inibidores de c-aril glicosídeo sglt2
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Year of Publication 27.07.2021
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Year of Publication 27.07.2021
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composto inibidor de c-aril glicosídeo sglt2, composição farmacêutica e combinação
Gang Wu, William N. Washburn, Philip M. Sher, Bruce Ellsworth, Wei Meng
Year of Publication 25.05.2021
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compostos inibidores de sglt2, composição farmacêutica e uso dos referidos compostos
WILLIAM N. WASHBURN, GANG WU, PHILIP M. SHER, BRUCE ELLSWORTH, WEI MENG
Year of Publication 25.05.2021
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Year of Publication 25.05.2021
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Carboxyl-promoted enhancement of selectivity for the β 3 adrenergic receptor. Negative charge of the sulfonic acid BMS-187413 introduces-β 3 binding selectivity
Sher, Philip M., Mathur, Arvind, Fisher, Liesl G., Wu, Gang, Skwish, Stephen, Michel, Inge M., Seiler, Steven M., Dickinson, Kenneth E.J.
Published in Bioorganic & medicinal chemistry letters (1997)
Published in Bioorganic & medicinal chemistry letters (1997)
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compostos inibidores de sglt2, composição farmacêutica e uso dos referidos compostos
Gang Wu, William N. Washburn, Philip M. Sher, Bruce Ellsworth, Wei Meng
Year of Publication 24.09.2019
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Year of Publication 24.09.2019
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C-ARYL GLUCOSIDE SGLT2 INHIBITORS AND METHOD
ELLSWORTH BRUCE, WASHBURN WILLIAM N, SHER PHILIP M, WU GANG, MENG WEI
Year of Publication 13.02.2014
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Year of Publication 13.02.2014
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