Preclinical pharmacology and pharmacokinetics of AZD3783, a selective 5-hydroxytryptamine 1B receptor antagonist
Zhang, Minli, Zhou, Diansong, Wang, Yi, Maier, Donna L, Widzowski, Daniel V, Sobotka-Briner, Cynthia D, Brockel, Becky J, Potts, William M, Shenvi, Ashok B, Bernstein, Peter R, Pierson, M Edward
Published in The Journal of pharmacology and experimental therapeutics (01.11.2011)
Published in The Journal of pharmacology and experimental therapeutics (01.11.2011)
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The mechanism of gamma-secretase: multiple inhibitor binding sites for transition state analogs and small molecule inhibitors
Tian, Gaochao, Ghanekar, Smita V, Aharony, David, Shenvi, Ashok B, Jacobs, Robert T, Liu, Xiaodong, Greenberg, Barry D
Published in The Journal of biological chemistry (01.08.2003)
Published in The Journal of biological chemistry (01.08.2003)
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Design, Synthesis, and SAR of Tachykinin Antagonists: Modulation of Balance in NK1/NK2 Receptor Antagonist Activity
Albert, Jeffrey S, Aharony, David, Andisik, Donald, Barthlow, Herbert, Bernstein, Peter R, Bialecki, Russell A, Dedinas, Robert, Dembofsky, Bruce T, Hill, Daniel, Kirkland, Karin, Koether, Gerard M, Kosmider, Benedict J, Ohnmacht, Cyrus, Palmer, William, Potts, William, Rumsey, William, Shen, Lihong, Shenvi, Ashok, Sherwood, Scott, Warwick, Paul J, Russell, Keith
Published in Journal of medicinal chemistry (29.08.2002)
Published in Journal of medicinal chemistry (29.08.2002)
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Pharmacological Characterization of ZD6021: A Novel, Orally Active Antagonist of the Tachykinin Receptors
Rumsey, W L, Aharony, D, Bialecki, R A, Abbott, B M, Barthlow, H G, Caccese, R, Ghanekar, S, Lengel, D, McCarthy, M, Wenrich, B, Undem, B, Ohnmacht, C, Shenvi, A, Albert, J S, Brown, F, Bernstein, P R, Russell, K
Published in The Journal of pharmacology and experimental therapeutics (01.07.2001)
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Published in The Journal of pharmacology and experimental therapeutics (01.07.2001)
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Nitrogen-15 NMR spectroscopy of the catalytic-triad histidine of a serine protease in peptide boronic acid inhibitor complexes
Bachovchin, William W, Wong, Winona Y. L, Farr-Jones, Shauna, Shenvi, Ashok B, Kettner, Charles A
Published in Biochemistry (Easton) (04.10.1988)
Published in Biochemistry (Easton) (04.10.1988)
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The Mechanism of γ-Secretase
Tian, Gaochao, Ghanekar, Smita V., Aharony, David, Shenvi, Ashok B., Jacobs, Robert T., Liu, Xiaodong, Greenberg, Barry D.
Published in The Journal of biological chemistry (01.08.2003)
Published in The Journal of biological chemistry (01.08.2003)
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Discovery of novel, orally active dual NK1/NK2 antagonists
BERNSTEIN, Peter R, AHARONY, David, KOSMIDER, Benedict J, KIRKLAND, Karin, OHNMACHT, Cyrus J, POTTS, William, RUMSEY, William L, LIHONG SHEN, SHENVI, Ashok, SHERWOOD, Scott, STOLLMAN, David, RUSSELL, Keith, ALBERT, Jeffrey S, ANDISIK, Donald, BARTHLOW, Herbert G, BIALECKI, Russell, DAVENPORT, Timothy, DEDINAS, Robert F, DEMBOFSKY, Bruce T, KOETHER, Gerard
Published in Bioorganic & medicinal chemistry letters (22.10.2001)
Published in Bioorganic & medicinal chemistry letters (22.10.2001)
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Design, synthesis, and SAR of tachykinin antagonists: modulation of balance in NK(1)/NK(2) receptor antagonist activity
Albert, Jeffrey S, Aharony, David, Andisik, Donald, Barthlow, Herbert, Bernstein, Peter R, Bialecki, Russell A, Dedinas, Robert, Dembofsky, Bruce T, Hill, Daniel, Kirkland, Karin, Koether, Gerard M, Kosmider, Benedict J, Ohnmacht, Cyrus, Palmer, William, Potts, William, Rumsey, William, Shen, Lihong, Shenvi, Ashok, Sherwood, Scott, Warwick, Paul J, Russell, Keith
Published in Journal of medicinal chemistry (29.08.2002)
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Published in Journal of medicinal chemistry (29.08.2002)
Journal Article
Design, Synthesis, and SAR of Tachykinin Antagonists: Modulation of Balance in NK 1 /NK 2 Receptor Antagonist Activity
Albert, Jeffrey S., Aharony, David, Andisik, Donald, Barthlow, Herbert, Bernstein, Peter R., Bialecki, Russell A., Dedinas, Robert, Dembofsky, Bruce T., Hill, Daniel, Kirkland, Karin, Koether, Gerard M., Kosmider, Benedict J., Ohnmacht, Cyrus, Palmer, William, Potts, William, Rumsey, William, Shen, Lihong, Shenvi, Ashok, Sherwood, Scott, Warwick, Paul J., Russell, Keith
Published in Journal of medicinal chemistry (01.08.2002)
Published in Journal of medicinal chemistry (01.08.2002)
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Journal Article
Discovery of novel, orally active dual NK 1/NK 2 antagonists
Bernstein, Peter R., Aharony, David, Albert, Jeffrey S., Andisik, Donald, Barthlow, Herbert G., Bialecki, Russell, Davenport, Timothy, Dedinas, Robert F., Dembofsky, Bruce T., Koether, Gerard, Kosmider, Benedict J., Kirkland, Karin, Ohnmacht, Cyrus J., Potts, William, Rumsey, William L., Shen, Lihong, Shenvi, Ashok, Sherwood, Scott, Stollman, David, Russell, Keith
Published in Bioorganic & medicinal chemistry letters (2001)
Published in Bioorganic & medicinal chemistry letters (2001)
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4-Alkylpiperidines related to SR-48968: Potent antagonists of the neurokinin-2 (NK 2) receptor
Jacobs, Robert T., Shenvi, Ashok B., Mauger, Russell C., Ulatowski, Terrance G., Aharony, David, Buckner, Carl K.
Published in Bioorganic & medicinal chemistry letters (21.07.1998)
Published in Bioorganic & medicinal chemistry letters (21.07.1998)
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Journal Article
The Mechanism of γ-Secretase
Gaochao Tian, Smita V. Ghanekar, David Aharony, Ashok B. Shenvi, Robert T. Jacobs, Xiaodong Liu, Barry D. Greenberg
Published in The Journal of biological chemistry (01.08.2003)
Published in The Journal of biological chemistry (01.08.2003)
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Journal Article
Recovery of rat nasal mucosa from the effects of aminopeptidase inhibitors
Hussain, M A, Koval, C A, Shenvi, A B, Aungst, B J
Published in Journal of pharmaceutical sciences (01.05.1990)
Published in Journal of pharmaceutical sciences (01.05.1990)
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