Structure-based design and screening of inhibitors for an essential bacterial GTPase, Der
Hwang, Jihwan, Tseitin, Vladimir, Ramnarayan, Kal, Shenderovich, Mark D, Inouye, Masayori
Published in Journal of antibiotics (01.05.2012)
Published in Journal of antibiotics (01.05.2012)
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Journal Article
Structural analysis of an HIV‐1 protease I47A mutant resistant to the protease inhibitor lopinavir
Kagan, Ron M., Shenderovich, Mark D., Heseltine, Peter N.R., Ramnarayan, Kal
Published in Protein science (01.07.2005)
Published in Protein science (01.07.2005)
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Journal Article
Structure‐based phenotyping predicts HIV‐1 protease inhibitor resistance
Shenderovich, Mark D., Kagan, Ron M., Heseltine, Peter N.R., Ramnarayan, Kal
Published in Protein science (01.08.2003)
Published in Protein science (01.08.2003)
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Journal Article
Solution Conformations of Potent Bicyclic Antagonists of Oxytocin by Nuclear Magnetic Resonance Spectroscopy and Molecular Dynamics Simulations
Shenderovich, Mark D, Kövér, Katalin E, Wilke, Susanne, Collins, Nathan, Hruby, Victor J
Published in Journal of the American Chemical Society (25.06.1997)
Published in Journal of the American Chemical Society (25.06.1997)
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Journal Article
De Novo Design, Synthesis, and Biological Activities of High-Affinity and Selective Non-Peptide Agonists of the δ-Opioid Receptor
Liao, Subo, Alfaro-Lopez, Josue, Shenderovich, Mark D, Hosohata, Keiko, Lin, Jun, Li, Xiaoping, Stropova, Dagmar, Davis, Peg, Jernigan, Kevin A, Porreca, Frank, Yamamura, Henry I, Hruby, Victor J
Published in Journal of medicinal chemistry (19.11.1998)
Published in Journal of medicinal chemistry (19.11.1998)
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Journal Article
Probing the Stereochemical Requirements for Receptor Recognition of δ Opioid Agonists through Topographic Modifications in Position 1
Qian, Xinhua, Shenderovich, Mark D, Kövér, Katalin E, Davis, Peg, Horváth, Robert, Zalewska, Teresa, Yamamura, Henry I, Porreca, Frank, Hruby, Victor J
Published in Journal of the American Chemical Society (07.08.1996)
Published in Journal of the American Chemical Society (07.08.1996)
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Journal Article
Substitution of the Side-Chain-Constrained Amino Acids β-Methyl-2‘,6‘-Dimethyl-4‘-Methoxytyrosine in Position 2 of a Bicyclic Oxytocin Analogue Provides Unique Insights into the Bioactive Topography of Oxytocin Antagonists
Liao, Subo, Shenderovich, Mark D, Zhang, Zhigang, Maletinska, Lenka, Slaninova, Jirina, Hruby, Victor J
Published in Journal of the American Chemical Society (29.07.1998)
Published in Journal of the American Chemical Society (29.07.1998)
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Journal Article
COMPOSITIONS AND THERAPEUTIC USES OF IKK-RELATED KINASE EPSILON AND TANKBINDING KINASE 1 INHIBITORS
HOARAU CHRISTOPHE, RICHARDS BURT, SHENDEROVICH MARK D, BURSAVICH MATTHEW GREGORY, DASTRUP DAVID M, MCLEOD DONALD A, BARTEL PAUL L, SUZUKI KAZUYUKI, HOLCOMB RYAN C, SEBAHAR PAUL R, HALTER ROBERT J
Year of Publication 24.04.2014
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Year of Publication 24.04.2014
Patent
Newly discovered stereochemical requirements in the side-chain conformation of .delta. opioid agonists for recognizing opioid .delta. receptors
Qian, Xinhua, Koever, Katalin E, Shenderovich, Mark D, Lou, Bih-Show, Misicka, Aleksandra, Zalewska, Teresa, Horvath, Robert, Davis, Peg, Bilsky, E. J
Published in Journal of medicinal chemistry (01.06.1994)
Published in Journal of medicinal chemistry (01.06.1994)
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Journal Article
Topographical Amino Acid Substitution in Position 10 of Glucagon Leads to Antagonists/Partial Agonists with Greater Binding Differences
Azizeh, Bassem Y, Shenderovich, Mark D, Trivedi, Dev, Li, Guigen, Sturm, Noel S, Hruby, Victor J
Published in Journal of medicinal chemistry (21.06.1996)
Published in Journal of medicinal chemistry (21.06.1996)
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Journal Article
The Role of Phenylalanine at Position 6 in Glucagon's Mechanism of Biological Action: Multiple Replacement Analogues of Glucagon
Azizeh, Bassem Y, Ahn, Jung-Mo, Caspari, Rael, Shenderovich, Mark D, Trivedi, Dev, Hruby, Victor J
Published in Journal of medicinal chemistry (01.08.1997)
Published in Journal of medicinal chemistry (01.08.1997)
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Journal Article
AMINO-PYRIMIDINE COMPOUNDS AS INHIBITORS OF TBKL AND/OR IKK EPSILON
HOLCOMB RYAN, RICHARDS BURT, SHENDEROVICH MARK D, YAGER KRAIG M, BURSAVICH MATTHEW GREGORY, WETTSTEIN DANIEL A, MCLEOD DONALD A, YUNGAI ASHANTAI J, BARTEL PAUL L, SUZUKI KAZUYUKI, SEBAHAR PAUL R, HALTER ROBERT J
Year of Publication 16.10.2012
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Year of Publication 16.10.2012
Patent
Exploration of the conformational space of oxytocin and arginine-vasopressin using the electrostatically driven Monte Carlo and molecular dynamics methods
Liwo, Adam, Tempczyk, Anna, Oldziej, Stanislaw, Shenderovich, Mark D., Hruby, Victor J., Talluri, Sekhar, Ciarkowski, Jerzy, Kasprzykowski, Franciszek, Lankiewicz, Leszek, Grzonka, Zbigniew
Published in Biopolymers (01.02.1996)
Published in Biopolymers (01.02.1996)
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Journal Article
The stereochemical requirements of the novel δ-opioid selective dipeptide antagonist TMT-Tic
Liao, Subo, Lin, Jun, Shenderovich, Mark D., Han, Yinglin, Hasohata, Keiko, Davis, Peg, Qiu, Wei, Porreca, Frank, Yamamura, Henry I., Hruby, Victor J.
Published in Bioorganic & medicinal chemistry letters (02.12.1997)
Published in Bioorganic & medicinal chemistry letters (02.12.1997)
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Journal Article
Conformational analysis of β-methyl-para-nitrophenylalanine stereoisomers of cyclo[D-Pen2, D-Pen5]enkephalin by NMR spectroscopy and conformational energy calculations
Shenderovich, Mark D., Kövér, Katalin E., Nikiforovich, Gregory V., Jiao, Ding, Hruby, Victor J.
Published in Biopolymers (01.02.1996)
Published in Biopolymers (01.02.1996)
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Journal Article
COMPOUNDS AND THERAPEUTIC USES THEREOF
KUMAR, DANGE VIJAY, YAGER, KRAIG M, TANGALLAPALLY, RAJENDRA, SLATTUM, PAUL M, SHENDEROVICH, MARK D, KIM, SE-HO
Year of Publication 01.04.2015
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Year of Publication 01.04.2015
Patent