TREM2‐dependent microglial function is essential for remyelination and subsequent neuroprotection
Wang, Yuanyuan, Kyauk, Roxanne V., Shen, Yun‐An A., Xie, Luke, Reichelt, Mike, Lin, Han, Jiang, Zhiyu, Ngu, Hai, Shen, Kimberle, Greene, Jacob J., Sheng, Morgan, Yuen, Tracy J.
Published in Glia (01.05.2023)
Published in Glia (01.05.2023)
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Micropillar arrays as a high-throughput screening platform for therapeutics in multiple sclerosis
Mei, Feng, Fancy, Stephen P J, Shen, Yun-An A, Niu, Jianqin, Zhao, Chao, Presley, Bryan, Miao, Edna, Lee, Seonok, Mayoral, Sonia R, Redmond, Stephanie A, Etxeberria, Ainhoa, Xiao, Lan, Franklin, Robin J M, Green, Ari, Hauser, Stephen L, Chan, Jonah R
Published in Nature medicine (01.08.2014)
Published in Nature medicine (01.08.2014)
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Initiation of CNS Myelination in the Optic Nerve Is Dependent on Axon Caliber
Mayoral, Sonia R., Etxeberria, Ainhoa, Shen, Yun-An A., Chan, Jonah R.
Published in Cell reports (Cambridge) (16.10.2018)
Published in Cell reports (Cambridge) (16.10.2018)
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Disease-associated oligodendrocyte responses across neurodegenerative diseases
Pandey, Shristi, Shen, Kimberle, Lee, Seung-Hye, Shen, Yun-An A., Wang, Yuanyuan, Otero-García, Marcos, Kotova, Natalya, Vito, Stephen T., Laufer, Benjamin I., Newton, Dwight F., Rezzonico, Mitchell G., Hanson, Jesse E., Kaminker, Joshua S., Bohlen, Christopher J., Yuen, Tracy J., Friedman, Brad A.
Published in Cell reports (Cambridge) (23.08.2022)
Published in Cell reports (Cambridge) (23.08.2022)
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Accelerated remyelination during inflammatory demyelination prevents axonal loss and improves functional recovery
Mei, Feng, Lehmann-Horn, Klaus, Shen, Yun-An A, Rankin, Kelsey A, Stebbins, Karin J, Lorrain, Daniel S, Pekarek, Kara, A Sagan, Sharon, Xiao, Lan, Teuscher, Cory, von Büdingen, H-Christian, Wess, Jürgen, Lawrence, J Josh, Green, Ari J, Fancy, Stephen Pj, Zamvil, Scott S, Chan, Jonah R
Published in eLife (27.09.2016)
Published in eLife (27.09.2016)
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Somatodendritic Expression of JAM2 Inhibits Oligodendrocyte Myelination
Redmond, Stephanie A., Mei, Feng, Eshed-Eisenbach, Yael, Osso, Lindsay A., Leshkowitz, Dena, Shen, Yun-An A., Kay, Jeremy N., Aurrand-Lions, Michel, Lyons, David A., Peles, Elior, Chan, Jonah R.
Published in Neuron (Cambridge, Mass.) (17.08.2016)
Published in Neuron (Cambridge, Mass.) (17.08.2016)
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Selective Estrogen Receptor Modulators Enhance CNS Remyelination Independent of Estrogen Receptors
Rankin, Kelsey A, Mei, Feng, Kim, Kicheol, Shen, Yun-An A, Mayoral, Sonia R, Desponts, Caroline, Lorrain, Daniel S, Green, Ari J, Baranzini, Sergio E, Chan, Jonah R, Bove, Riley
Published in The Journal of neuroscience (20.03.2019)
Published in The Journal of neuroscience (20.03.2019)
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Neurite outgrowth inhibitor Nogo-A establishes spatial segregation and extent of oligodendrocyte myelination
Chong, S. Y. Christin, Rosenberg, Sheila S., Fancy, Stephen P. J., Zhao, Chao, Shen, Yun-An A., Hahn, Angela T., McGee, Aaron W., Xu, Xiaomei, Zheng, Binhai, Zhang, Li I., Rowitch, David H., Franklin, Robin J. M., Lu, Q. Richard, Chan, Jonah R.
Published in Proceedings of the National Academy of Sciences - PNAS (24.01.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (24.01.2012)
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Phosphorylation of LKB1/Par-4 establishes Schwann cell polarity to initiate and control myelin extent
Shen, Yun-An A., Chen, Yan, Dao, Dang Q., Mayoral, Sonia R., Wu, Laiman, Meijer, Dies, Ullian, Erik M., Chan, Jonah R., Lu, Q. Richard
Published in Nature communications (26.09.2014)
Published in Nature communications (26.09.2014)
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The myelin oligodendrocyte glycoprotein directly binds nerve growth factor to modulate central axon circuitry
von Büdingen, H-Christian, Mei, Feng, Greenfield, Ariele, Jahn, Sarah, Shen, Yun-An A, Reid, Hugh H, McKemy, David D, Chan, Jonah R
Published in The Journal of cell biology (14.09.2015)
Published in The Journal of cell biology (14.09.2015)
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Modeling CNS Myelination Using Micropillar Arrays
Huang, Nan-Xing, Shen, Yun-An A, Mei, Feng
Published in Methods in molecular biology (Clifton, N.J.) (2018)
Published in Methods in molecular biology (Clifton, N.J.) (2018)
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Multiple sclerosis risk gene Mertk is required for microglial activation and subsequent remyelination
Shen, Kimberle, Reichelt, Mike, Kyauk, Roxanne V., Ngu, Hai, Shen, Yun-An A., Foreman, Oded, Modrusan, Zora, Friedman, Brad A., Sheng, Morgan, Yuen, Tracy J.
Published in Cell reports (Cambridge) (09.03.2021)
Published in Cell reports (Cambridge) (09.03.2021)
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Assessing the role of the cadherin/catenin complex at the Schwann cell-axon interface and in the initiation of myelination
Lewallen, Kathryn A, Shen, Yun-An A, De la Torre, Asia R, Ng, Benjamin K, Meijer, Dies, Chan, Jonah R
Published in The Journal of neuroscience (23.02.2011)
Published in The Journal of neuroscience (23.02.2011)
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Clemastine rescues myelination defects and promotes functional recovery in hypoxic brain injury
Cree, Bruce A C, Niu, Jianqin, Hoi, Kimberly K, Zhao, Chao, Caganap, Scott D, Henry, Roland G, Dao, Dang Q, Zollinger, Daniel R, Mei, Feng, Shen, Yun-An A, Franklin, Robin J M, Ullian, Erik M, Xiao, Lan, Chan, Jonah R, Fancy, Stephen P J
Published in Brain (London, England : 1878) (01.01.2018)
Published in Brain (London, England : 1878) (01.01.2018)
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Journal Article
Clemastine rescues myelination defects and promotes functional recovery in hypoxic brain injury
Cree, Bruce A C, Niu, Jianqin, Hoi, Kimberly K, Zhao, Chao, Caganap, Scott D, Henry, Roland G, Dao, Dang Q, Zollinger, Daniel R, Mei, Feng, Shen, Yun-An A, Franklin, Robin J M, Ullian, Erik M, Xiao, Lan, Chan, Jonah R, Fancy, Stephen P J
Published in Brain (London, England : 1878) (01.01.2018)
Published in Brain (London, England : 1878) (01.01.2018)
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Fenebrutinib, a Bruton's tyrosine kinase inhibitor, blocks distinct human microglial signaling pathways
Langlois, Julie, Lange, Simona, Ebeling, Martin, Macnair, Will, Schmucki, Roland, Li, Cenxiao, DeGeer, Jonathan, Sudharshan, Tania J J, Yong, V Wee, Shen, Yun-An, Harp, Christopher, Collin, Ludovic, Keaney, James
Published in Journal of neuroinflammation (27.10.2024)
Published in Journal of neuroinflammation (27.10.2024)
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Neutral or detrimental effects of TREM2 agonist antibodies in preclinical models of Alzheimer's Disease and Multiple Sclerosis
Etxeberria, Ainhoa, Shen, Yun-An A, Vito, Steve, Silverman, Sean, Imperio, Jose, Lalehzadeh, Guita, Soung, Allison, Du, Changchun, Xie, Luke, Choy, Man Kin, Hsiao, Yi-Chun, Ngu, Hai, Cho, Chang Hoon, Ghosh, Soumitra, Novikova, Gloriia, Rezzonico, Mitchell G, Leahey, Rebecca, Weber, Martin, Gogineni, Alvin, Elstrott, Justin, Xiong, Monica, Greene, Jacob J, Stark, Kimberly L, Chan, Pamela, Roth, Gillie A, Adrian, Max, Li, Qingling, Choi, Meena, Wong, Weng Ruh, Sandoval, Wendy, Foreman, Oded, Nugent, Alicia A, Friedman, Brad A, Sadekar, Shraddha, Hötzel, Isidro, Hansen, David V, Chih, Ben, Yuen, Tracy J, Weimer, Robby M, Easton, Amy, Meilandt, William J, Bohlen, Christopher J
Published in The Journal of neuroscience (17.07.2024)
Published in The Journal of neuroscience (17.07.2024)
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Subcutaneous ocrelizumab in multiple sclerosis: Results of the Phase 1b OCARINA I study
Newsome, Scott D, Goldstick, Lawrence, Robertson, Derrick S, Bowen, James D, Naismith, Robert T, Townsend, Ben, Figueiredo, Catarina, Kletzl, Heidemarie, Giraudon, Mylene, Bortolami, Oscar, Zecevic, Dusanka, Giacobino, Caroline, Clinch, Susanne, Shen, Yun-An, Deol-Bhullar, Gurpreet, Bermel, Robert A
Published in Annals of clinical and translational neurology (26.10.2024)
Published in Annals of clinical and translational neurology (26.10.2024)
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Author Correction: Micropillar arrays as a high-throughput screening platform for therapeutics in multiple sclerosis
Mei, Feng, Fancy, Stephen P J, Shen, Yun-An A, Niu, Jianqin, Zhao, Chao, Presley, Bryan, Miao, Edna, Lee, Seonok, Mayoral, Sonia R, Redmond, Stephanie A, Etxeberria, Ainhoa, Xiao, Lan, Franklin, Robin J M, Green, Ari, Hauser, Stephen L, Chan, Jonah R
Published in Nature medicine (01.09.2024)
Published in Nature medicine (01.09.2024)
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