BOXR1030, an anti-GPC3 CAR with exogenous GOT2 expression, shows enhanced T cell metabolism and improved anti-cell line derived tumor xenograft activity
Hickman, Taylor L, Choi, Eugene, Whiteman, Kathleen R, Muralidharan, Sujatha, Pai, Tapasya, Johnson, Tyler, Parikh, Avani, Friedman, Taylor, Gilbert, Madaline, Shen, Binzhang, Barron, Luke, McGinness, Kathleen E, Ettenberg, Seth A, Motz, Greg T, Weiss, Glen J, Jensen-Smith, Amy
Published in PloS one (04.05.2022)
Published in PloS one (04.05.2022)
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Engineering a thermoregulated intein-modified xylanase into maize for consolidated lignocellulosic biomass processing
BINZHANG SHEN, XUEGUANG SUN, LUCERO, Hector, GRAY, Benjamin, EKBORG, Nathan A, DONGCHENG ZHANG, SCHLEY JOHNSON, Jeremy C, LAZAR, Gabor, RAAB, R. Michael, XIAO ZUO, SHILLING, Taran, APGAR, James, ROSS, Mary, BOUGRI, Oleg, SAMOYLOV, Vladimir, PARKER, Matthew, HANCOCK, Elaina
Published in Nature biotechnology (01.11.2012)
Published in Nature biotechnology (01.11.2012)
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Uridine Addition after MicroRNA-Directed Cleavage
Shen, Binzhang, Goodman, Howard M.
Published in Science (American Association for the Advancement of Science) (05.11.2004)
Published in Science (American Association for the Advancement of Science) (05.11.2004)
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A predictive model of intein insertion site for use in the engineering of molecular switches
Apgar, James, Ross, Mary, Zuo, Xiao, Dohle, Sarah, Sturtevant, Derek, Shen, Binzhang, de la Vega, Humberto, Lessard, Philip, Lazar, Gabor, Raab, R Michael
Published in PloS one (23.05.2012)
Published in PloS one (23.05.2012)
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The Highly Recombinogenic bz Locus Lies in an Unusually Gene-Rich Region of the Maize Genome
Fu, H, Park, W, Yan, X, Zheng, Z, Shen, B, Dooner, H K
Published in Proceedings of the National Academy of Sciences - PNAS (17.07.2001)
Published in Proceedings of the National Academy of Sciences - PNAS (17.07.2001)
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VRK1 Is a Synthetic-Lethal Target in VRK2-Deficient Glioblastoma
Shields, Julie A, Meier, Samuel R, Bandi, Madhavi, Mulkearns-Hubert, Erin E, Hajdari, Nicole, Ferdinez, Maria Dam, Engel, Justin L, Silver, Daniel J, Shen, Binzhang, Zhang, Wenhai, Hubert, Christopher G, Mitchell, Kelly, Shakya, Sajina, Zhao, Shan-Chuan, Bejnood, Alborz, Zhang, Minjie, Tjin Tham Sjin, Robert, Wilker, Erik, Lathia, Justin D, Andersen, Jannik N, Chen, Yingnan, Li, Fang, Weber, Barbara, Huang, Alan, Emmanuel, Natasha
Published in Cancer research (Chicago, Ill.) (02.11.2022)
Published in Cancer research (Chicago, Ill.) (02.11.2022)
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Ubiquitinated PCNA Drives USP1 Synthetic Lethality in Cancer
Simoneau, Antoine, Engel, Justin L, Bandi, Madhavi, Lazarides, Katherine, Liu, Shangtao, Meier, Samuel R, Choi, Ashley H, Zhang, Hongxiang, Shen, Binzhang, Martires, Lauren, Gotur, Deepali, Pham, Truc V, Li, Fang, Gu, Lina, Gong, Shanzhong, Zhang, Minjie, Wilker, Erik, Pan, Xuewen, Whittington, Douglas A, Throner, Scott, Maxwell, John P, Chen, Yingnan, Yu, Yi, Huang, Alan, Andersen, Jannik N, Feng, Tianshu
Published in Molecular cancer therapeutics (01.02.2023)
Published in Molecular cancer therapeutics (01.02.2023)
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Abstract 2184: BOXR1030: A first-in-class CAR T-cell therapy co-expressing GOT2 enhances T-cell metabolic function for the treatment of GPC3-positive solid tumors
Choi, Eugene, Whiteman, Kathleen, Pai, Tapasya, Hickman, Taylor, Johnson, Tyler, Friedman, Taylor, Parikh, Avani, Gilbert, Madaline, Shen, Binzhang, Weiss, Glen J., Ettenberg, Seth, McGinness, Kathleen E., Motz, Greg
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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CNSC-36. VRK1 IS A PARALOG SYNTHETIC LETHAL TARGET IN VRK2-METHYLATED GLIOBLASTOMA
Shields, Julie, Meier, Samuel, Bandi, Madhavi, Ferdinez, Maria Dam, Engel, Justin, Mulkearns-Hubert, Erin, Hajdari, Nicole, Shen, Binzhang, Hubert, Christopher, Mitchell, Kelly, Zhang, Wenhai, Zhao, Shan-chuan, Bejnood, Alborz, Zhang, Minjie, Sjin, Robert Tjin Tham, Wilker, Erik, Lathia, Justin, Andersen, Jannik, Chen, Yingnan, Li, Fang, Weber, Barbara, Huang, Alan, Emmanuel, Natasha
Published in Neuro-oncology (Charlottesville, Va.) (14.11.2022)
Published in Neuro-oncology (Charlottesville, Va.) (14.11.2022)
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Abstract 1224: UMIBB: A novel nonparametric Bayesian method improves robustness and sensitivity of analysis in pooled CRISPR-Cas9 screens leveraging unique molecular identifiers
Choi, Ashley, Meier, Samuel, Fenoglio, Silvia, Feng, Tianshu, Engel, Justin, Shen, Binzhang, Liu, Shangtao, Teng, Teng, Khendu, Tenzing, Huang, Alan, Andersen, Jannik, Pan, Xuewen, Yu, Yi
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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Abstract 4631: Evaluation of the impact of homozygous MTAP truncations on the activity and selectivity of MTA-cooperative PRMT5 inhibitors
Tonini, Matthew R., Mignault, Andre A., Whittington, Douglas A., Lombardo, Steven A., Shen, Binzhang, Stowe, Hannah, Yoda, Satoshi, Liu, Shangtao, Zhang, Minjie, Cottrell, Kevin M., Meier, Samuel R., Rego, Heidi, Morawiak, Jennifer, Hooper, Ellen, Yu, Yi, DiBenedetto, Heather, Crystal, Adam S., Teng, Briggs, Kimberly
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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Abstract 3363: LIG1 inactivation selectively inhibits growth of BRCA1 mutant cells in vitro and in vivo
Martires, Lauren, Ahronian, Leanne G., Pratt, Charlotte, Das, Nikitha, Zhang, Xiaobin, Whittington, Douglas A., Zhang, Hongxiang, Shen, Binzhang, Come, Jon, McCarren, Patrick, Liu, Mu-Sen, Min, Chengyin, Feng, Tianshu, Jahic, Haris, Brophy, Eric, Aird, Daniel, Andersen, Jannik N., Huang, Alan, Li, Fang, Mallender, William D., Nicholson, Hilary E.
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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Abstract 4527: TNG348 is synergistic with PARP inhibitors in tumor models with elevated replication stress
Simoneau, Antoine, Wu, Hsin-Jung, Pratt, Charlotte, Comer, Grace, Liu, Shangtao, Meier, Samuel, Khendu, Tenzing, Choi, Ashley, Zhang, Hongxiang, Shen, Binzhang, Whittington, Douglas, Sudsakorn, Sirimas, Zhang, Wenhai, Yu, Yi, Chen, Yingnan, Haines, Brian, Crystal, Adam, Andersen, Jannik N., Maxwell, John, Throner, Scott
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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Abstract B098: Unbiased in vitro and in vivo drug anchor screens identify mechanisms of resistance and sensitization for MTA-cooperative PRMT5 inhibitors in MTAP-deleted cancer models
Lombardo, Steven, Tonini, Matthew R, Grove, Lauren, Fenoglio, Silvia, Tepper, James, Shen, Binzhang, Stowe, Hannah, Liu, Shangtao, Meier, Samuel R, Choi, Ashley H, Khendu, Tenzing, Yu, Yi, Cottrell, Kevin M, Maxwell, John P, Andersen, Jannik N, Huang, Alan, Briggs, Kimberly J, Teng, Teng
Published in Molecular cancer therapeutics (01.12.2023)
Published in Molecular cancer therapeutics (01.12.2023)
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Abstract C048: Inducible activation of sgRNA libraries in tumor xenografts empowers large-scale in vivo target discovery screens
Fenoglio, Silvia, Tepper, James, Grove, Lauren, Uijttewaal, Esther CH, Bejnood, Alborz, Yu, Yi, Wu, Hsin-Jung, Devault, Annabel, Liu, Shangtao, Shen, Binzhang, Meier, Samuel R, Choi, Ashley H, Khendu, Tenzing, Stowe, Hannah, Zhang, Minjie, Haines, Brian B, Huang, Alan, Andersen, Jannik N, Pan, Xuewen, Elling, Ulrich, Teng, Teng
Published in Molecular cancer therapeutics (01.12.2023)
Published in Molecular cancer therapeutics (01.12.2023)
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Improved performance of Eimeria-infected chickens fed corn expressing a single-domain antibody against interleukin-10
Lessard, Philip A, Parker, Matthew, Bougri, Oleg, Shen, Binzhang, Samoylov, Vladimir, Broomhead, Jon, Li, Xuemei, Raab, R Michael
Published in Nature food (01.02.2020)
Published in Nature food (01.02.2020)
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Abstract 4968: Characterization of the clinical development candidate TNG348 as a potent and selective inhibitor of USP1 for the treatment of BRCA1/2mut cancers
Simoneau, Antoine, Wu, Hsin-Jung, Bandi, Madhavi, Lazarides, Katherine, Sun, Sining, Liu, Shangtao, Meier, Samuel, Choi, Ashley, Zhang, Hongxiang, Shen, Binzhang, Whittington, Douglas, Sudsakorn, Sirimas, Zhang, Wenhai, Yu, Yi, Liu, Yong, Liang, Colin, Palmieri, Michael, Chen, Yingnan, Haines, Brian, Tsai, Alice, Zhang, Minjie, Huang, Alan, Andersen, Jannik, Feng, Tianshu, Throner, Scott, Maxwell, John
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Abstract 2603: USP1 inhibitor synthetic lethality in BRCA1-mutant cancer is driven by PCNA ubiquitination
Engel, Justin, Bandi, Madhavi, Simoneau, Antione, Lazarides, Katherine, Gotur, Deepali, Pham, Truc, Liu, Shangtao, Meier, Samuel, Choi, Ashley, Zhang, Hongxiang, Shen, Binzhang, Li, Fang, Whittington, Douglas, Gong, Shanzhong, Pan, Xuewen, Yu, Yi, Gu, Lina, Throner, Scott, Maxwell, John, Chen, Yingnan, Huang, Alan, Andersen, Jannik, Feng, Tianshu
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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