Pharmacology-based ranking of anti-cancer drugs to guide clinical development of cancer immunotherapy combinations
Lemaire, Vincent, Shemesh, Colby S, Rotte, Anand
Published in Journal of Experimental and Clinical Cancer Research (01.10.2021)
Published in Journal of Experimental and Clinical Cancer Research (01.10.2021)
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Journal Article
Book Review
Disposition and Pharmacology of a GalNAc3-conjugated ASO Targeting Human Lipoprotein (a) in Mice
Yu, Rosie Z, Graham, Mark J, Post, Noah, Riney, Stan, Zanardi, Thomas, Hall, Shannon, Burkey, Jennifer, Shemesh, Colby S, Prakash, Thazha P, Seth, Punit P, Swayze, Eric E, Geary, Richard S, Wang, Yanfeng, Henry, Scott
Published in Molecular therapy. Nucleic acids (03.05.2016)
Published in Molecular therapy. Nucleic acids (03.05.2016)
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Journal Article
Population pharmacokinetics, exposure-safety, and immunogenicity of atezolizumab in pediatric and young adult patients with cancer
Shemesh, Colby S., Chanu, Pascal, Jamsen, Kris, Wada, Russ, Rossato, Gianluca, Donaldson, Francis, Garg, Amit, Winter, Helen, Ruppel, Jane, Wang, Xin, Bruno, Rene, Jin, Jin, Girish, Sandhya
Published in Journal for immunotherapy of cancer (21.11.2019)
Published in Journal for immunotherapy of cancer (21.11.2019)
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Journal Article
Development of a pediatric physiologically-based pharmacokinetic model to support recommended dosing of atezolizumab in children with solid tumors
Huang, Weize, Stader, Felix, Chan, Phyllis, Shemesh, Colby S., Chen, Yuan, Gill, Katherine L., Jones, Hannah M., Li, Linzhong, Rossato, Gianluca, Wu, Benjamin, Jin, Jin Y., Chanu, Pascal
Published in Frontiers in pharmacology (26.09.2022)
Published in Frontiers in pharmacology (26.09.2022)
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Journal Article
Indocyanine green loaded liposome nanocarriers for photodynamic therapy using human triple negative breast cancer cells
Shemesh, Colby S, Hardy, Claire W, Yu, David S, Fernandez, Brian, Zhang, Hailing, Ph.D
Published in Photodiagnosis and photodynamic therapy (01.06.2014)
Published in Photodiagnosis and photodynamic therapy (01.06.2014)
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Journal Article
Integrated Two‐Analyte Population Pharmacokinetic Model of Polatuzumab Vedotin in Patients With Non‐Hodgkin Lymphoma
Lu, Dan, Lu, Tong, Gibiansky, Leonid, Li, Xiaobin, Li, Chunze, Agarwal, Priya, Shemesh, Colby S., Shi, Rong, Dere, Randall C., Hirata, Jamie, Miles, Dale, Chanu, Pascal, Girish, Sandhya, Jin, Jin Yan
Published in CPT: pharmacometrics and systems pharmacology (01.01.2020)
Published in CPT: pharmacometrics and systems pharmacology (01.01.2020)
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Journal Article
Pharmacokinetic and Pharmacodynamic Investigations of ION-353382, a Model Antisense Oligonucleotide: Using Alpha-2-Macroglobulin and Murinoglobulin Double-Knockout Mice
Shemesh, Colby S., Yu, Rosie Z., Gaus, Hans J., Seth, Punit P., Swayze, Eric E., Bennett, Frank C., Geary, Richard S., Henry, Scott P., Wang, Yanfeng
Published in Nucleic acid therapeutics (01.08.2016)
Published in Nucleic acid therapeutics (01.08.2016)
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Journal Article
Atezolizumab and Bevacizumab in Patients with Unresectable Hepatocellular Carcinoma: Pharmacokinetic and Safety Assessments Based on Hepatic Impairment Status and Geographic Region
Shemesh, Colby S., Chan, Phyllis, Shao, Hui, Xu, Derek-Zhen, Combs, Daniel, Vadhavkar, Shweta, Bruno, René, Wu, Benjamin
Published in Liver cancer (Basel ) (01.09.2021)
Published in Liver cancer (Basel ) (01.09.2021)
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Journal Article
Elucidation of the Biotransformation Pathways of a Galnac3-conjugated Antisense Oligonucleotide in Rats and Monkeys
Shemesh, Colby S, Yu, Rosie Z, Gaus, Hans J, Greenlee, Sarah, Post, Noah, Schmidt, Karsten, Migawa, Michael T, Seth, Punit P, Zanardi, Thomas A, Prakash, Thazha P, Swayze, Eric E, Henry, Scott P, Wang, Yanfeng
Published in Molecular therapy. Nucleic acids (2016)
Published in Molecular therapy. Nucleic acids (2016)
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Journal Article
Personalized Cancer Vaccines: Clinical Landscape, Challenges, and Opportunities
Shemesh, Colby S., Hsu, Joy C., Hosseini, Iraj, Shen, Ben-Quan, Rotte, Anand, Twomey, Patrick, Girish, Sandhya, Wu, Benjamin
Published in Molecular therapy (03.02.2021)
Published in Molecular therapy (03.02.2021)
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Journal Article
Assessment of the Drug Interaction Potential of Unconjugated and GalNAc3-Conjugated 2′-MOE-ASOs
Shemesh, Colby S., Yu, Rosie Z., Warren, Mark S., Liu, Michael, Jahic, Mirza, Nichols, Brandon, Post, Noah, Lin, Song, Norris, Daniel A., Hurh, Eunju, Huang, Jane, Watanabe, Tanya, Henry, Scott P., Wang, Yanfeng
Published in Molecular therapy. Nucleic acids (01.12.2017)
Published in Molecular therapy. Nucleic acids (01.12.2017)
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Journal Article
Pan‐cancer population pharmacokinetics and exposure‐safety and ‐efficacy analyses of atezolizumab in patients with high tumor mutational burden
Shemesh, Colby S., Chan, Phyllis, Legrand, Fatema A., Shames, David S., Das Thakur, Meghna, Shi, Jane, Bailey, Lorna, Vadhavkar, Shweta, He, Xian, Zhang, Wei, Bruno, René
Published in Pharmacology research & perspectives (01.12.2020)
Published in Pharmacology research & perspectives (01.12.2020)
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Journal Article
Atezolizumab for children and young adults with previously treated solid tumours, non-Hodgkin lymphoma, and Hodgkin lymphoma (iMATRIX): a multicentre phase 1–2 study
Geoerger, Birgit, Zwaan, C Michel, Marshall, Lynley V, Michon, Jean, Bourdeaut, Franck, Casanova, Michela, Corradini, Nadège, Rossato, Gianluca, Farid-Kapadia, Mufiza, Shemesh, Colby S, Hutchinson, Katherine E, Donaldson, Francis, Liao, Minlei, Caron, Hubert, Trippett, Tanya
Published in The lancet oncology (01.01.2020)
Published in The lancet oncology (01.01.2020)
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Journal Article
Phase I pharmacokinetic, safety, and preliminary efficacy study of tiragolumab in combination with atezolizumab in Chinese patients with advanced solid tumors
Shemesh, Colby S., Wang, Yongsheng, An, Andrew, Ding, Hao, Chan, Phyllis, Liu, Qi, Chen, Yih-Wen, Wu, Benjamin, Wu, Qiong, Wang, Xian
Published in Cancer chemotherapy and pharmacology (01.07.2024)
Published in Cancer chemotherapy and pharmacology (01.07.2024)
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Journal Article
Early Decision Making in a Randomized Phase II Trial of Atezolizumab in Biliary Tract Cancer Using a Tumor Growth Inhibition-Survival Modeling Framework
Shemesh, Colby S, Chan, Phyllis, Marchand, Mathilde, Gonçalves, Antonio, Vadhavkar, Shweta, Wu, Benjamin, Li, Chunze, Jin, Jin Y, Hack, Stephen P, Bruno, Rene
Published in Clinical pharmacology and therapeutics (01.09.2023)
Published in Clinical pharmacology and therapeutics (01.09.2023)
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Journal Article
Atezolizumab plus Magrolimab, Niraparib, or Tocilizumab versus Atezolizumab Monotherapy in Platinum-Refractory Metastatic Urothelial Carcinoma: A Phase Ib/II Open-Label, Multicenter, Randomized Umbrella Study (MORPHEUS Urothelial Carcinoma)
Drakaki, Alexandra, Powles, Thomas, Bamias, Aristotelis, Martin-Liberal, Juan, Shin, Sang Joon, Friedlander, Terence, Tosi, Diego, Park, Chandler, Gomez-Roca, Carlos, Joly Lobbedez, Florence, Castellano, Daniel, Morales-Barrera, Rafael, Moreno-Candilejo, Irene, Fléchon, Aude, Yuen, Kobe, Rishipathak, Deepali, DuPree, Kelly, Young, Fiona, Michielin, Francesca, Shemesh, Colby S., Steinberg, Elizabeth E., Williams, Patrick, Lee, Jae Lyun
Published in Clinical cancer research (01.11.2023)
Published in Clinical cancer research (01.11.2023)
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Journal Article
PARP inhibition with rucaparib alone followed by combination with atezolizumab: Phase Ib COUPLET clinical study in advanced gynaecological and triple-negative breast cancers
Kristeleit, Rebecca, Leary, Alexandra, Oaknin, Ana, Redondo, Andres, George, Angela, Chui, Stephen, Seiller, Aicha, Liste-Hermoso, Mario, Willis, Jenna, Shemesh, Colby S., Xiao, Jim, Lin, Kevin K., Molinero, Luciana, Guan, Yinghui, Ray-Coquard, Isabelle, Mileshkin, Linda
Published in British journal of cancer (01.09.2024)
Published in British journal of cancer (01.09.2024)
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