Discovery of hit compounds for methyl-lysine reader proteins from a target class DNA-encoded library
Shell, Devan J., Rectenwald, Justin M., Buttery, Peter H., Johnson, Rebecca L., Foley, Caroline A., Guduru, Shiva K.R., Uguen, Mélanie, Rubiano, Juanita Sanchez, Zhang, Xindi, Li, Fengling, Norris-Drouin, Jacqueline L., Axtman, Matthew, Brian Hardy, P., Vedadi, Masoud, Frye, Stephen V., James, Lindsey I., Pearce, Kenneth H.
Published in SLAS discovery (01.12.2022)
Published in SLAS discovery (01.12.2022)
Get full text
Journal Article
Identification of Covalent Cyclic Peptide Inhibitors in mRNA Display
Iskandar, Sabrina E., Chiou, Lilly F., Leisner, Tina M., Shell, Devan J., Norris-Drouin, Jacqueline L., Vaziri, Cyrus, Pearce, Kenneth H., Bowers, Albert A.
Published in Journal of the American Chemical Society (19.07.2023)
Published in Journal of the American Chemical Society (19.07.2023)
Get full text
Journal Article
Discovery of a 53BP1 Small Molecule Antagonist Using a Focused DNA-Encoded Library Screen
Shell, Devan J., Foley, Caroline A., Wang, Qinhong, Smith, Chelsea M., Guduru, Shiva K. R., Zeng, Hong, Dong, Aiping, Norris-Drouin, Jacqueline L., Axtman, Matthew, Hardy, P. Brian, Gupta, Gaorav, Halabelian, Levon, Frye, Stephen V., James, Lindsey I., Pearce, Kenneth H.
Published in Journal of medicinal chemistry (26.10.2023)
Published in Journal of medicinal chemistry (26.10.2023)
Get full text
Journal Article
SETDB1 Triple Tudor Domain Ligand, (R,R)‑59, Promotes Methylation of Akt1 in Cells
Uguen, Mélanie, Deng, Yu, Li, Fengling, Shell, Devan J., Norris-Drouin, Jacqueline L., Stashko, Michael A., Ackloo, Suzanne, Arrowsmith, Cheryl H., James, Lindsey I., Liu, Pengda, Pearce, Kenneth H., Frye, Stephen V.
Published in ACS chemical biology (18.08.2023)
Published in ACS chemical biology (18.08.2023)
Get full text
Journal Article
Potent and Selective SETDB1 Covalent Negative Allosteric Modulator Reduces Methyltransferase Activity in Cells
Uguen, Mélanie, Shell, Devan J, Silva, Madhushika, Deng, Yu, Li, Fengling, Szewczyk, Magdalena M, Yang, Ka, Zhao, Yani, Stashko, Michael A, Norris-Drouin, Jacqueline L, Waybright, Jarod M, Beldar, Serap, Rectenwald, Justin M, Mordant, Angie L, Webb, Thomas S, Herring, Laura E, Arrowsmith, Cheryl H, Ackloo, Suzanne, Gygi, Steven P, McGinty, Robert K, Barsyte-Lovejoy, Dalia, Liu, Pengda, Halabelian, Levon, James, Lindsey I, Pearce, Kenneth H, Frye, Stephen V
Published in bioRxiv (28.09.2024)
Published in bioRxiv (28.09.2024)
Get full text
Journal Article
SETDB1 Triple Tudor Domain Ligand, ( R,R )-59, Promotes Methylation of Akt1 in Cells
Uguen, Mélanie, Deng, Yu, Li, Fengling, Shell, Devan J, Norris-Drouin, Jacqueline L, Stashko, Michael A, Ackloo, Suzanne, Arrowsmith, Cheryl H, James, Lindsey I, Liu, Pengda, Pearce, Kenneth H, Frye, Stephen V
Published in bioRxiv : the preprint server for biology (10.05.2023)
Get more information
Published in bioRxiv : the preprint server for biology (10.05.2023)
Journal Article