Stress granules regulate stress-induced paraspeckle assembly
An, Haiyan, Tan, Jing Tong, Shelkovnikova, Tatyana A
Published in The Journal of cell biology (02.12.2019)
Published in The Journal of cell biology (02.12.2019)
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Compromised paraspeckle formation as a pathogenic factor in FUSopathies
Shelkovnikova, Tatyana A, Robinson, Hannah K, Troakes, Claire, Ninkina, Natalia, Buchman, Vladimir L
Published in Human molecular genetics (01.05.2014)
Published in Human molecular genetics (01.05.2014)
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ALS-linked cytoplasmic FUS assemblies are compositionally different from physiological stress granules and sequester hnRNPA3, a novel modifier of FUS toxicity
An, Haiyan, Litscher, Gioana, Watanabe, Naruaki, Wei, Wenbin, Hashimoto, Tadafumi, Iwatsubo, Takeshi, Buchman, Vladimir L., Shelkovnikova, Tatyana A.
Published in Neurobiology of disease (01.01.2022)
Published in Neurobiology of disease (01.01.2022)
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Journal Article
Protective paraspeckle hyper-assembly downstream of TDP-43 loss of function in amyotrophic lateral sclerosis
Shelkovnikova, Tatyana A, Kukharsky, Michail S, An, Haiyan, Dimasi, Pasquale, Alexeeva, Svetlana, Shabir, Osman, Heath, Paul R, Buchman, Vladimir L
Published in Molecular neurodegeneration (01.06.2018)
Published in Molecular neurodegeneration (01.06.2018)
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Journal Article
NEAT1 and paraspeckles in neurodegenerative diseases: A missing lnc found?
An, Haiyan, Williams, Non G., Shelkovnikova, Tatyana A.
Published in Non-coding RNA research (01.12.2018)
Published in Non-coding RNA research (01.12.2018)
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Journal Article
ALS-linked FUS mutations confer loss and gain of function in the nucleus by promoting excessive formation of dysfunctional paraspeckles
An, Haiyan, Skelt, Lucy, Notaro, Antonietta, Highley, J Robin, Fox, Archa H, La Bella, Vincenzo, Buchman, Vladimir L, Shelkovnikova, Tatyana A
Published in Acta neuropathologica communications (14.01.2019)
Published in Acta neuropathologica communications (14.01.2019)
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Journal Article
Long non-coding RNA NEAT1_1 ameliorates TDP-43 toxicity in in vivo models of TDP-43 proteinopathy
Matsukawa, Koji, Kukharsky, Michail S., Park, Sei-Kyoung, Park, Sangeun, Watanabe, Naruaki, Iwatsubo, Takeshi, Hashimoto, Tadafumi, Liebman, Susan W., Shelkovnikova, Tatyana A.
Published in RNA biology (02.11.2021)
Published in RNA biology (02.11.2021)
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The master energy homeostasis regulator PGC-1α exhibits an mRNA nuclear export function
Mihaylov, Simeon R., Castelli, Lydia M., Lin, Ya-Hui, Gül, Aytac, Soni, Nikita, Hastings, Christopher, Flynn, Helen R., Păun, Oana, Dickman, Mark J., Snijders, Ambrosius P., Goldstone, Robert, Bandmann, Oliver, Shelkovnikova, Tatyana A., Mortiboys, Heather, Ultanir, Sila K., Hautbergue, Guillaume M.
Published in Nature communications (07.09.2023)
Published in Nature communications (07.09.2023)
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Stress-induced TDP-43 nuclear condensation causes splicing loss of function and STMN2 depletion
Huang, Wan-Ping, Ellis, Brittany C.S., Hodgson, Rachel E., Sanchez Avila, Anna, Kumar, Vedanth, Rayment, Jessica, Moll, Tobias, Shelkovnikova, Tatyana A.
Published in Cell reports (Cambridge) (23.07.2024)
Published in Cell reports (Cambridge) (23.07.2024)
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Calcium-responsive transactivator (CREST) toxicity is rescued by loss of PBP1/ATXN2 function in a novel yeast proteinopathy model and in transgenic flies
Park, Sangeun, Park, Sei-Kyoung, Watanabe, Naruaki, Hashimoto, Tadafumi, Iwatsubo, Takeshi, Shelkovnikova, Tatyana A, Liebman, Susan W
Published in PLoS genetics (01.08.2019)
Published in PLoS genetics (01.08.2019)
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Fused in Sarcoma (FUS) Protein Lacking Nuclear Localization Signal (NLS) and Major RNA Binding Motifs Triggers Proteinopathy and Severe Motor Phenotype in Transgenic Mice
Shelkovnikova, Tatyana A., Peters, Owen M., Deykin, Alexey V., Connor-Robson, Natalie, Robinson, Hannah, Ustyugov, Alexey A., Bachurin, Sergey O., Ermolkevich, Tatyana G., Goldman, Igor L., Sadchikova, Elena R., Kovrazhkina, Elena A., Skvortsova, Veronica I., Ling, Shuo-Chien, Da Cruz, Sandrine, Parone, Philippe A., Buchman, Vladimir L., Ninkina, Natalia N.
Published in The Journal of biological chemistry (30.08.2013)
Published in The Journal of biological chemistry (30.08.2013)
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Chronically stressed or stress-preconditioned neurons fail to maintain stress granule assembly
Shelkovnikova, Tatyana A, Dimasi, Pasquale, Kukharsky, Michail S, An, Haiyan, Quintiero, Annamaria, Schirmer, Claire, Buée, Luc, Galas, Marie-Christine, Buchman, Vladimir L
Published in Cell death & disease (11.05.2017)
Published in Cell death & disease (11.05.2017)
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Journal Article
Frameshift peptides alter the properties of truncated FUS proteins in ALS-FUS
An, Haiyan, Rabesahala de Meritens, Camille, Buchman, Vladimir L, Shelkovnikova, Tatyana A
Published in Molecular brain (13.05.2020)
Published in Molecular brain (13.05.2020)
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Selective pattern of motor system damage in gamma-synuclein transgenic mice mirrors the respective pathology in amyotrophic lateral sclerosis
Peters, Owen M, Millership, Steven, Shelkovnikova, Tatyana A, Soto, Ileana, Keeling, Lora, Hann, Anthony, Marsh-Armstrong, Nicholas, Buchman, Vladimir L, Ninkina, Natalia
Published in Neurobiology of disease (01.10.2012)
Published in Neurobiology of disease (01.10.2012)
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Journal Article
TDP-43 in nuclear condensates: where, how, and why
Lang, Ruaridh, Hodgson, Rachel E, Shelkovnikova, Tatyana A
Published in Biochemical Society transactions (28.08.2024)
Published in Biochemical Society transactions (28.08.2024)
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