Targeting Xenobiotic Nuclear Receptors PXR and CAR to Prevent Cobicistat Hepatotoxicity
Shehu, Amina I, Zhu, Junjie, Li, Jianhua, Lu, Jie, McMahon, Deborah, Xie, Wen, Gonzalez, Frank J, Ma, Xiaochao
Published in Toxicological sciences (27.04.2021)
Published in Toxicological sciences (27.04.2021)
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Journal Article
Biotransformation of Cobicistat: Metabolic Pathways and Enzymes
Wang, Pengcheng, Shehu, Amina I, Liu, Ke, Lu, Jie, Ma, Xiaochao
Published in Drug metabolism letters (01.01.2016)
Published in Drug metabolism letters (01.01.2016)
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Journal Article
Pregnane X receptor activation potentiates ritonavir hepatotoxicity
Shehu, Amina I, Lu, Jie, Wang, Pengcheng, Zhu, Junjie, Wang, Yue, Yang, Da, McMahon, Deborah, Xie, Wen, Gonzalez, Frank J, Ma, Xiaochao
Published in The Journal of clinical investigation (01.07.2019)
Published in The Journal of clinical investigation (01.07.2019)
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Journal Article
Identification of Novel Pathways in Idelalisib Metabolism and Bioactivation
Zhu, Junjie, Wang, Pengcheng, Shehu, Amina I, Lu, Jie, Bi, Huichang, Ma, Xiaochao
Published in Chemical research in toxicology (16.07.2018)
Published in Chemical research in toxicology (16.07.2018)
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Journal Article
CYP1A1 and 1B1-mediated metabolic pathways of dolutegravir, an HIV integrase inhibitor
Zhu, Junjie, Wang, Pengcheng, Li, Feng, Lu, Jie, Shehu, Amina I., Xie, Wen, McMahon, Deborah, Ma, Xiaochao
Published in Biochemical pharmacology (01.12.2018)
Published in Biochemical pharmacology (01.12.2018)
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Journal Article
Enzymes and Pathways of Kavain Bioactivation and Biotransformation
Wang, Pengcheng, Zhu, Junjie, Shehu, Amina I, Lu, Jie, Chen, Jing, Zhong, Xiao-bo, Ma, Xiaochao
Published in Chemical research in toxicology (15.07.2019)
Published in Chemical research in toxicology (15.07.2019)
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Journal Article
Liver metabolomics in a mouse model of erythropoietic protoporphyria
Wang, Pengcheng, Sachar, Madhav, Guo, Grace L., Shehu, Amina I., Lu, Jie, Zhong, Xiao-bo, Ma, Xiaochao
Published in Biochemical pharmacology (01.08.2018)
Published in Biochemical pharmacology (01.08.2018)
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Journal Article
The pregnane X receptor in tuberculosis therapeutics
Shehu, Amina I, Li, Guangming, Xie, Wen, Ma, Xiaochao
Published in Expert opinion on drug metabolism & toxicology (02.01.2016)
Published in Expert opinion on drug metabolism & toxicology (02.01.2016)
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Journal Article
The Opportunities of Metabolomics in Drug Safety Evaluation
Wang, Pengcheng, Shehu, Amina I., Ma, Xiaochao
Published in Current pharmacology reports (01.02.2017)
Published in Current pharmacology reports (01.02.2017)
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Journal Article
Deficiency of N-acetyltransferase increases the interactions of isoniazid with endobiotics in mouse liver
Wang, Pengcheng, Shehu, Amina I., Lu, Jie, Joshi, Rujuta H., Venkataramanan, Raman, Sugamori, Kim S., Grant, Denis M., Zhong, Xiao-bo, Ma, Xiaochao
Published in Biochemical pharmacology (01.12.2017)
Published in Biochemical pharmacology (01.12.2017)
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Journal Article
The essential role of the transporter ABCG2 in the pathophysiology of erythropoietic protoporphyria
Wang, Pengcheng, Sachar, Madhav, Lu, Jie, Shehu, Amina I, Zhu, Junjie, Chen, Jing, Liu, Ke, Anderson, Karl E, Xie, Wen, Gonzalez, Frank J, Klaassen, Curtis D, Ma, Xiaochao
Published in Science advances (01.09.2019)
Published in Science advances (01.09.2019)
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Journal Article
CYP1A1 and 1B1-mediated metabolic pathways of dolutegravir, an HIV-1 integrase inhibitor
Zhu, Junjie, Wang, Pengcheng, Li, Feng, Lu, Jie, Shehu, Amina I, Xie, Wen, McMahon, Deborah, Ma, Xiaochao
Published in Biochemical pharmacology (17.10.2018)
Published in Biochemical pharmacology (17.10.2018)
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Journal Article