iPSC toolbox for understanding and repairing disrupted brain circuits in autism
Chiola, Simone, Edgar, Nicolas U, Shcheglovitov, Aleksandr
Published in Molecular psychiatry (01.01.2022)
Published in Molecular psychiatry (01.01.2022)
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Journal Article
SHANK3 and IGF1 restore synaptic deficits in neurons from 22q13 deletion syndrome patients
SHCHEGLOVITOV, Aleksandr, SHCHEGLOVITOVA, Olesya, DOLMETSCH, Ricardo E, YAZAWA, Masayuki, PORTMANN, Thomas, RUI SHU, SEBASTIANO, Vittorio, KRAWISZ, Anna, FROEHLICH, Wendy, BERNSTEIN, Jonathan A, HALLMAYER, Joachim F
Published in Nature (London) (14.11.2013)
Published in Nature (London) (14.11.2013)
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Journal Article
MicroRNA-mediated conversion of human fibroblasts to neurons
YOO, Andrew S, SUN, Alfred X, LI LI, SHCHEGLOVITOV, Aleksandr, PORTMANN, Thomas, YULONG LI, LEE-MESSER, Chris, DOLMETSCH, Ricardo E, TSIEN, Richard W, CRABTREE, Gerald R
Published in Nature (London) (11.08.2011)
Published in Nature (London) (11.08.2011)
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Journal Article
Modeling human telencephalic development and autism-associated SHANK3 deficiency using organoids generated from single neural rosettes
Wang, Yueqi, Chiola, Simone, Yang, Guang, Russell, Chad, Armstrong, Celeste J, Wu, Yuanyuan, Spampanato, Jay, Tarboton, Paisley, Ullah, H M Arif, Edgar, Nicolas U, Chang, Amelia N, Harmin, David A, Bocchi, Vittoria Dickinson, Vezzoli, Elena, Besusso, Dario, Cui, Jun, Cattaneo, Elena, Kubanek, Jan, Shcheglovitov, Aleksandr
Published in Nature communications (06.10.2022)
Published in Nature communications (06.10.2022)
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Journal Article
Orientation of the calcium channel beta relative to the alpha(1)2.2 subunit is critical for its regulation of channel activity
Vitko, Iuliia, Shcheglovitov, Aleksandr, Baumgart, Joel P, Arias-Olguín, Imilla I, Murbartián, Janet, Arias, Juan Manuel, Perez-Reyes, Edward
Published in PloS one (2008)
Published in PloS one (2008)
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Journal Article
Special issue on stem cell and tissue engineering in development, disease, and repair
Shcheglovitov, Aleksandr, Rao, Mahendra, Yoo, Andrew
Published in Developmental dynamics (01.01.2019)
Published in Developmental dynamics (01.01.2019)
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Journal Article
Timothy syndrome is associated with activity-dependent dendritic retraction in rodent and human neurons
Krey, Jocelyn F, Paşca, Sergiu P, Shcheglovitov, Aleksandr, Yazawa, Masayuki, Schwemberger, Rachel, Rasmusson, Randall, Dolmetsch, Ricardo E
Published in Nature neuroscience (01.02.2013)
Published in Nature neuroscience (01.02.2013)
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Journal Article
Using iPSC-derived neurons to uncover cellular phenotypes associated with Timothy syndrome
Paşca, Sergiu P, Portmann, Thomas, Voineagu, Irina, Yazawa, Masayuki, Shcheglovitov, Aleksandr, Paşca, Anca M, Cord, Branden, Palmer, Theo D, Chikahisa, Sachiko, Nishino, Seiji, Bernstein, Jonathan A, Hallmayer, Joachim, Geschwind, Daniel H, Dolmetsch, Ricardo E
Published in Nature medicine (01.12.2011)
Published in Nature medicine (01.12.2011)
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Journal Article
LRRK2 Mutant iPSC-Derived DA Neurons Demonstrate Increased Susceptibility to Oxidative Stress
Nguyen, Ha Nam, Byers, Blake, Cord, Branden, Shcheglovitov, Aleksandr, Byrne, James, Gujar, Prachi, Kee, Kehkooi, Schüle, Birgitt, Dolmetsch, Ricardo E., Langston, William, Palmer, Theo D., Pera, Renee Reijo
Published in Cell stem cell (04.03.2011)
Published in Cell stem cell (04.03.2011)
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Journal Article
Defective AMPA-mediated synaptic transmission and morphology in human neurons with hemizygous SHANK3 deletion engrafted in mouse prefrontal cortex
Chiola, Simone, Napan, Kandy L, Wang, Yueqi, Lazarenko, Roman M, Armstrong, Celeste J, Cui, Jun, Shcheglovitov, Aleksandr
Published in Molecular psychiatry (01.09.2021)
Published in Molecular psychiatry (01.09.2021)
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Journal Article
Mechanisms by which a CACNA1H mutation in epilepsy patients increases seizure susceptibility
Eckle, Veit‐Simon, Shcheglovitov, Aleksandr, Vitko, Iuliia, Dey, Deblina, Yap, Chan Choo, Winckler, Bettina, Perez‐Reyes, Edward
Published in The Journal of physiology (15.02.2014)
Published in The Journal of physiology (15.02.2014)
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Journal Article
Identification of 22q13 genes most likely to contribute to Phelan McDermid syndrome
Mitz, Andrew R, Philyaw, Travis J, Boccuto, Luigi, Shcheglovitov, Aleksandr, Sarasua, Sara M, Kaufmann, Walter E, Thurm, Audrey
Published in European journal of human genetics : EJHG (01.03.2018)
Published in European journal of human genetics : EJHG (01.03.2018)
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Journal Article
Direct in vivo assessment of human stem cell graft–host neural circuits
Byers, Blake, Lee, Hyun Joo, Liu, Jia, Weitz, Andrew J., Lin, Peter, Zhang, Pengbo, Shcheglovitov, Aleksandr, Dolmetsch, Ricardo, Pera, Renee Reijo, Lee, Jin Hyung
Published in NeuroImage (Orlando, Fla.) (01.07.2015)
Published in NeuroImage (Orlando, Fla.) (01.07.2015)
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Journal Article
Secreted Reporter Assay Enables Quantitative and Longitudinal Monitoring of Neuronal Activity
Santos, Ana C, Chiola, Simone, Yang, Guang, Shcheglovitov, Aleksandr, Park, Sungjin
Published in eNeuro (01.09.2021)
Published in eNeuro (01.09.2021)
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Journal Article
Selectivity signatures of three isoforms of recombinant T-type Ca2+ channels
Shcheglovitov, Aleksandr, Kostyuk, Platon, Shuba, Yaroslav
Published in Biochimica et biophysica acta (01.06.2007)
Published in Biochimica et biophysica acta (01.06.2007)
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Journal Article
Molecular and biophysical basis of glutamate and trace metal modulation of voltage-gated Ca(v)2.3 calcium channels
Shcheglovitov, Aleksandr, Vitko, Iuliia, Lazarenko, Roman M, Orestes, Peihan, Todorovic, Slobodan M, Perez-Reyes, Edward
Published in The Journal of general physiology (01.03.2012)
Published in The Journal of general physiology (01.03.2012)
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Journal Article
Stim1 Binds to and Inhibits CaV1.2 Voltage Gated Calcium Channels
Park, Chan Young, Shcheglovitov, Aleksandr, Dolmetsch, Ricardo E.
Published in Biophysical journal (01.01.2010)
Published in Biophysical journal (01.01.2010)
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Journal Article