Optimization of 1,3,4-Benzotriazepine-Based CCK2 Antagonists to Obtain Potent, Orally Active Inhibitors of Gastrin-Mediated Gastric Acid Secretion
McDonald, Iain M, Black, James W, Buck, Ildiko M, Dunstone, David J, Griffin, Eric P, Harper, Elaine A, Hull, Robert A. D, Kalindjian, S. Barret, Lilley, Elliot J, Linney, Ian D, Pether, Michael J, Roberts, Sonia P, Shaxted, Mark E, Spencer, John, Steel, Katherine I. M, Sykes, David A, Walker, Martin K, Watt, Gillian F, Wright, Laurence, Wright, Paul T, Xun, Wei
Published in Journal of medicinal chemistry (28.06.2007)
Published in Journal of medicinal chemistry (28.06.2007)
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Journal Article
Discovery and Characterization of Novel, Potent, Non-Peptide Parathyroid Hormone-1 Receptor Antagonists
McDonald, Iain M, Austin, Carol, Buck, Ildiko M, Dunstone, David J, Gaffen, John, Griffin, Eric, Harper, Elaine A, Hull, Robert A. D, Kalindjian, S. Barret, Linney, Ian D, Low, Caroline M. R, Patel, Dipa, Pether, Michael J, Raynor, Michelle, Roberts, Sonia P, Shaxted, Mark E, Spencer, John, Steel, Katherine I. M, Sykes, David A, Wright, Paul T, Xun, Wei
Published in Journal of medicinal chemistry (04.10.2007)
Published in Journal of medicinal chemistry (04.10.2007)
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Achiral, selective CCK2 receptor antagonists based on a 1,3,5-benzotriazepine-2,4-dione template
SPENCER, John, GAFFEN, John, GRIFFIN, Eric, HARPER, Elaine A, LINNEY, Ian D, MCDONALD, Iain M, ROBERTS, Sonia P, SHAXTED, Mark E, ADATIA, Trushar, BASHALL, Alan
Published in Bioorganic & medicinal chemistry (15.03.2008)
Published in Bioorganic & medicinal chemistry (15.03.2008)
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Journal Article
Optimization of the in Vitro and in Vivo Properties of a Novel Series of 2,4,5-Trisubstituted Imidazoles as Potent Cholecystokinin-2 (CCK2) Antagonists
Buck, Ildiko M, Black, James W, Cooke, Tracey, Dunstone, David J, Gaffen, John D, Griffin, Eric P, Harper, Elaine A, Hull, Robert A. D, Kalindjian, S. Barret, Lilley, Elliot J, Linney, Ian D, Low, Caroline M. R, McDonald, Iain M, Pether, Michael J, Roberts, Sonia P, Shankley, Nigel P, Shaxted, Mark E, Steel, Katherine I. M, Sykes, David A, Tozer, Matthew J, Watt, Gillian F, Walker, Martin K, Wright, Laurence, Wright, Paul T
Published in Journal of medicinal chemistry (03.11.2005)
Published in Journal of medicinal chemistry (03.11.2005)
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Erratum to “Achiral, selective CCK2 receptor antagonists based on a 1,3,5-benzotriazepine-2,4-dione template” [Bioorg. Med. Chem. 16 (2008) 2974–2983]
Spencer, John, Gaffen, John, Griffin, Eric, Harper, Elaine A., Linney, Ian D., McDonald, Iain M., Roberts, Sonia P., Shaxted, Mark E., Adatia, Trushar, Bashall, Alan
Published in Bioorganic & medicinal chemistry (15.08.2008)
Published in Bioorganic & medicinal chemistry (15.08.2008)
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Journal Article
Achiral, selective CCK 2 receptor antagonists based on a 1,3,5-benzotriazepine-2,4-dione template
Spencer, John, Gaffen, John, Griffin, Eric, Harper, Elaine A., Linney, Ian D., McDonald, Iain M., Roberts, Sonia P., Shaxted, Mark E., Adatia, Trushar, Bashall, Alan
Published in Bioorganic & medicinal chemistry (2008)
Published in Bioorganic & medicinal chemistry (2008)
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Journal Article
Erratum to “Achiral, selective CCK 2 receptor antagonists based on a 1,3,5-benzotriazepine-2,4-dione template” [Bioorg. Med. Chem. 16 (2008) 2974–2983]
Spencer, John, Gaffen, John, Griffin, Eric, Harper, Elaine A., Linney, Ian D., McDonald, Iain M., Roberts, Sonia P., Shaxted, Mark E., Adatia, Trushar, Bashall, Alan
Published in Bioorganic & medicinal chemistry (2008)
Published in Bioorganic & medicinal chemistry (2008)
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Journal Article
Optimization of 1,3,4-benzotriazepine-based CCK(2) antagonists to obtain potent, orally active inhibitors of gastrin-mediated gastric acid secretion
McDonald, Iain M, Black, James W, Buck, Ildiko M, Dunstone, David J, Griffin, Eric P, Harper, Elaine A, Hull, Robert A D, Kalindjian, S Barret, Lilley, Elliot J, Linney, Ian D, Pether, Michael J, Roberts, Sonia P, Shaxted, Mark E, Spencer, John, Steel, Katherine I M, Sykes, David A, Walker, Martin K, Watt, Gillian F, Wright, Laurence, Wright, Paul T, Xun, Wei
Published in Journal of medicinal chemistry (28.06.2007)
Get full text
Published in Journal of medicinal chemistry (28.06.2007)
Journal Article
Optimization of 1,3,4-Benzotriazepine-Based CCK 2 Antagonists to Obtain Potent, Orally Active Inhibitors of Gastrin-Mediated Gastric Acid Secretion
McDonald, Iain M., Black, James W., Buck, Ildiko M., Dunstone, David J., Griffin, Eric P., Harper, Elaine A., Hull, Robert A. D., Kalindjian, S. Barret, Lilley, Elliot J., Linney, Ian D., Pether, Michael J., Roberts, Sonia P., Shaxted, Mark E., Spencer, John, Steel, Katherine I. M., Sykes, David A., Walker, Martin K., Watt, Gillian F., Wright, Laurence, Wright, Paul T., Xun, Wei
Published in Journal of medicinal chemistry (01.06.2007)
Published in Journal of medicinal chemistry (01.06.2007)
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Journal Article