Disrupted glycosylation of lipids and proteins is a cause of neurodegeneration
Moll, Tobias, Shaw, Pamela J, Cooper-Knock, Johnathan
Published in Brain (London, England : 1878) (01.05.2020)
Published in Brain (London, England : 1878) (01.05.2020)
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Serum miRNAs miR-206, 143-3p and 374b-5p as potential biomarkers for amyotrophic lateral sclerosis (ALS)
Waller, Rachel, Goodall, Emily F, Milo, Marta, Cooper-Knock, Jonathan, Da Costa, Marc, Hobson, Esther, Kazoka, Mbombe, Wollff, Helen, Heath, Paul R, Shaw, Pamela J, Kirby, Janine
Published in Neurobiology of aging (01.07.2017)
Published in Neurobiology of aging (01.07.2017)
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The gut microbiome: a key player in the complexity of amyotrophic lateral sclerosis (ALS)
Boddy, Sarah L, Giovannelli, Ilaria, Sassani, Matilde, Cooper-Knock, Johnathan, Snyder, Michael P, Segal, Eran, Elinav, Eran, Barker, Lynne A, Shaw, Pamela J, McDermott, Christopher J
Published in BMC medicine (20.01.2021)
Published in BMC medicine (20.01.2021)
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Molecular pathways of motor neuron injury in amyotrophic lateral sclerosis
Ferraiuolo, Laura, Kirby, Janine, Grierson, Andrew J., Sendtner, Michael, Shaw, Pamela J.
Published in Nature reviews. Neurology (01.11.2011)
Published in Nature reviews. Neurology (01.11.2011)
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A review of Mendelian randomization in amyotrophic lateral sclerosis
Julian, Thomas H, Boddy, Sarah, Islam, Mahjabin, Kurz, Julian, Whittaker, Katherine J, Moll, Tobias, Harvey, Calum, Zhang, Sai, Snyder, Michael P, McDermott, Christopher, Cooper-Knock, Johnathan, Shaw, Pamela J
Published in Brain (London, England : 1878) (29.04.2022)
Published in Brain (London, England : 1878) (29.04.2022)
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Direct conversion of patient fibroblasts demonstrates non-cell autonomous toxicity of astrocytes to motor neurons in familial and sporadic ALS
Meyer, Kathrin, Ferraiuolo, Laura, Miranda, Carlos J., Likhite, Shibi, McElroy, Sohyun, Renusch, Samantha, Ditsworth, Dara, Lagier-Tourenne, Clotilde, Smith, Richard A., Ravits, John, Burghes, Arthur H., Shaw, Pamela J., Cleveland, Don W., Kolb, Stephen J., Kaspar, Brian K.
Published in Proceedings of the National Academy of Sciences - PNAS (14.01.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (14.01.2014)
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Oligodendrocytes contribute to motor neuron death in ALS via SOD1-dependent mechanism
Ferraiuolo, Laura, Meyer, Kathrin, Sherwood, Thomas W., Vick, Jonathan, Likhite, Shibi, Frakes, Ashley, Miranda, Carlos J., Braun, Lyndsey, Heath, Paul R., Pineda, Ricardo, Beattie, Christine E., Shaw, Pamela J., Askwith, Candice C., McTigue, Dana, Kaspar, Brian K.
Published in Proceedings of the National Academy of Sciences - PNAS (18.10.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (18.10.2016)
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Sequestration of multiple RNA recognition motif-containing proteins by C9orf72 repeat expansions
COOPER-KNOCK, Johnathan, WALSH, Matthew J, HAUTBERGUE, Guillaume M, SHAW, Pamela J, HIGGINBOTTOM, Adrian, HIGHLEY, J. Robin, DICKMAN, Mark J, EDBAUER, Dieter, INCE, Paul G, WHARTON, Stephen B, WILSON, Stuart A, KIRBY, Janine
Published in Brain (London, England : 1878) (01.07.2014)
Published in Brain (London, England : 1878) (01.07.2014)
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Small RNA Sequencing of Sporadic Amyotrophic Lateral Sclerosis Cerebrospinal Fluid Reveals Differentially Expressed miRNAs Related to Neural and Glial Activity
Waller, Rachel, Wyles, Matthew, Heath, Paul R, Kazoka, Mbombe, Wollff, Helen, Shaw, Pamela J, Kirby, Janine
Published in Frontiers in neuroscience (09.01.2018)
Published in Frontiers in neuroscience (09.01.2018)
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C9orf72 expansion disrupts ATM-mediated chromosomal break repair
Walker, Callum, Herranz-Martin, Saul, Karyka, Evangelia, Liao, Chunyan, Lewis, Katherine, Elsayed, Waheba, Lukashchuk, Vera, Chiang, Shih-Chieh, Ray, Swagat, Mulcahy, Padraig J, Jurga, Mateusz, Tsagakis, Ioannis, Iannitti, Tommaso, Chandran, Jayanth, Coldicott, Ian, De Vos, Kurt J, Hassan, Mohamed K, Higginbottom, Adrian, Shaw, Pamela J, Hautbergue, Guillaume M, Azzouz, Mimoun, El-Khamisy, Sherif F
Published in Nature neuroscience (01.09.2017)
Published in Nature neuroscience (01.09.2017)
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Dysregulation of astrocyte-motoneuron cross-talk in mutant superoxide dismutase 1-related amyotrophic lateral sclerosis
Ferraiuolo, Laura, Higginbottom, Adrian, Heath, Paul R., Barber, Sian, Greenald, David, Kirby, Janine, Shaw, Pamela J.
Published in Brain (London, England : 1878) (01.09.2011)
Published in Brain (London, England : 1878) (01.09.2011)
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Exome sequencing in amyotrophic lateral sclerosis implicates a novel gene, DNAJC7, encoding a heat-shock protein
Farhan, Sali M. K., Howrigan, Daniel P., Abbott, Liam E., Klim, Joseph R., Topp, Simon D., Byrnes, Andrea E., Churchhouse, Claire, Phatnani, Hemali, Smith, Bradley N., Rampersaud, Evadnie, Wu, Gang, Wuu, Joanne, Shatunov, Aleksey, Iacoangeli, Alfredo, Al Khleifat, Ahmad, Mordes, Daniel A., Ghosh, Sulagna, Eggan, Kevin, Rademakers, Rosa, McCauley, Jacob L., Schüle, Rebecca, Züchner, Stephan, Benatar, Michael, Taylor, J. Paul, Nalls, Michael, Gotkine, Marc, Shaw, Pamela J., Morrison, Karen E., Al-Chalabi, Ammar, Traynor, Bryan, Shaw, Christopher E., Goldstein, David B., Harms, Matthew B., Daly, Mark J., Neale, Benjamin M.
Published in Nature neuroscience (01.12.2019)
Published in Nature neuroscience (01.12.2019)
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Journal Article
C9orf72 expansion within astrocytes reduces metabolic flexibility in amyotrophic lateral sclerosis
Allen, Scott P, Hall, Benjamin, Woof, Ryan, Francis, Laura, Gatto, Noemi, Shaw, Allan C, Myszczynska, Monika, Hemingway, Jordan, Coldicott, Ian, Willcock, Amelia, Job, Lucy, Hughes, Rachel M, Boschian, Camilla, Bayatti, Nadhim, Heath, Paul R, Bandmann, Oliver, Mortiboys, Heather, Ferraiuolo, Laura, Shaw, Pamela J
Published in Brain (London, England : 1878) (01.12.2019)
Published in Brain (London, England : 1878) (01.12.2019)
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Astrocyte function and role in motor neuron disease: A future therapeutic target?
Blackburn, Daniel, Sargsyan, Siranush, Monk, Peter N., Shaw, Pamela J.
Published in Glia (01.09.2009)
Published in Glia (01.09.2009)
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Oxidative stress in ALS: A mechanism of neurodegeneration and a therapeutic target
Barber, Siân C., Mead, Richard J., Shaw, Pamela J.
Published in Biochimica et biophysica acta (01.11.2006)
Published in Biochimica et biophysica acta (01.11.2006)
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Mitochondrial Dysfunction in Alzheimer's Disease: A Biomarker of the Future?
Bell, Simon M, Barnes, Katy, De Marco, Matteo, Shaw, Pamela J, Ferraiuolo, Laura, Blackburn, Daniel J, Venneri, Annalena, Mortiboys, Heather
Published in Biomedicines (11.01.2021)
Published in Biomedicines (11.01.2021)
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