Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq
Filbin, Mariella G, Tirosh, Itay, Hovestadt, Volker, Shaw, McKenzie L, Escalante, Leah E, Mathewson, Nathan D, Neftel, Cyril, Frank, Nelli, Pelton, Kristine, Hebert, Christine M, Haberler, Christine, Yizhak, Keren, Gojo, Johannes, Egervari, Kristof, Mount, Christopher, van Galen, Peter, Bonal, Dennis M, Nguyen, Quang-De, Beck, Alexander, Sinai, Claire, Czech, Thomas, Dorfer, Christian, Goumnerova, Liliana, Lavarino, Cinzia, Carcaboso, Angel M, Mora, Jaume, Mylvaganam, Ravindra, Luo, Christina C, Peyrl, Andreas, Popović, Mara, Azizi, Amedeo, Batchelor, Tracy T, Frosch, Matthew P, Martinez-Lage, Maria, Kieran, Mark W, Bandopadhayay, Pratiti, Beroukhim, Rameen, Fritsch, Gerhard, Getz, Gad, Rozenblatt-Rosen, Orit, Wucherpfennig, Kai W, Louis, David N, Monje, Michelle, Slavc, Irene, Ligon, Keith L, Golub, Todd R, Regev, Aviv, Bernstein, Bradley E, Suvà, Mario L
Published in Science (American Association for the Advancement of Science) (20.04.2018)
Published in Science (American Association for the Advancement of Science) (20.04.2018)
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Dissecting hematopoietic and renal cell heterogeneity in adult zebrafish at single-cell resolution using RNA sequencing
Tang, Qin, Iyer, Sowmya, Lobbardi, Riadh, Moore, John C, Chen, Huidong, Lareau, Caleb, Hebert, Christine, Shaw, McKenzie L, Neftel, Cyril, Suva, Mario L, Ceol, Craig J, Bernards, Andre, Aryee, Martin, Pinello, Luca, Drummond, Iain A, Langenau, David M
Published in The Journal of experimental medicine (02.10.2017)
Published in The Journal of experimental medicine (02.10.2017)
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The landscape of tumor cell states and spatial organization in H3-K27M mutant diffuse midline glioma across age and location
Liu, Ilon, Jiang, Li, Samuelsson, Erik R., Marco Salas, Sergio, Beck, Alexander, Hack, Olivia A., Jeong, Daeun, Shaw, McKenzie L., Englinger, Bernhard, LaBelle, Jenna, Mire, Hafsa M., Madlener, Sibylle, Mayr, Lisa, Quezada, Michael A., Trissal, Maria, Panditharatna, Eshini, Ernst, Kati J., Vogelzang, Jayne, Gatesman, Taylor A., Halbert, Matthew E., Palova, Hana, Pokorna, Petra, Sterba, Jaroslav, Slaby, Ondrej, Geyeregger, Rene, Diaz, Aaron, Findlay, Izac J., Dun, Matthew D., Resnick, Adam, Suvà, Mario L., Jones, David T. W., Agnihotri, Sameer, Svedlund, Jessica, Koschmann, Carl, Haberler, Christine, Czech, Thomas, Slavc, Irene, Cotter, Jennifer A., Ligon, Keith L., Alexandrescu, Sanda, Yung, W. K. Alfred, Arrillaga-Romany, Isabel, Gojo, Johannes, Monje, Michelle, Nilsson, Mats, Filbin, Mariella G.
Published in Nature genetics (01.12.2022)
Published in Nature genetics (01.12.2022)
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An Integrative Model of Cellular States, Plasticity, and Genetics for Glioblastoma
Neftel, Cyril, Laffy, Julie, Filbin, Mariella G., Hara, Toshiro, Shore, Marni E., Rahme, Gilbert J., Richman, Alyssa R., Silverbush, Dana, Shaw, McKenzie L., Hebert, Christine M., Dewitt, John, Gritsch, Simon, Perez, Elizabeth M., Gonzalez Castro, L. Nicolas, Lan, Xiaoyang, Druck, Nicholas, Rodman, Christopher, Dionne, Danielle, Kaplan, Alexander, Bertalan, Mia S., Small, Julia, Pelton, Kristine, Becker, Sarah, Bonal, Dennis, Nguyen, Quang-De, Servis, Rachel L., Fung, Jeremy M., Mylvaganam, Ravindra, Mayr, Lisa, Gojo, Johannes, Haberler, Christine, Geyeregger, Rene, Czech, Thomas, Slavc, Irene, Nahed, Brian V., Curry, William T., Carter, Bob S., Wakimoto, Hiroaki, Brastianos, Priscilla K., Batchelor, Tracy T., Stemmer-Rachamimov, Anat, Martinez-Lage, Maria, Frosch, Matthew P., Stamenkovic, Ivan, Riggi, Nicolo, Rheinbay, Esther, Monje, Michelle, Rozenblatt-Rosen, Orit, Cahill, Daniel P., Patel, Anoop P., Hunter, Tony, Verma, Inder M., Ligon, Keith L., Louis, David N., Regev, Aviv, Bernstein, Bradley E., Tirosh, Itay, Suvà, Mario L.
Published in Cell (08.08.2019)
Published in Cell (08.08.2019)
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Resolving medulloblastoma cellular architecture by single-cell genomics
Hovestadt, Volker, Smith, Kyle S., Bihannic, Laure, Filbin, Mariella G., Shaw, McKenzie L., Baumgartner, Alicia, DeWitt, John C., Groves, Andrew, Mayr, Lisa, Weisman, Hannah R., Richman, Alyssa R., Shore, Marni E., Goumnerova, Liliana, Rosencrance, Celeste, Carter, Robert A., Phoenix, Timothy N., Hadley, Jennifer L., Tong, Yiai, Houston, Jim, Ashmun, Richard A., DeCuypere, Michael, Sharma, Tanvi, Flasch, Diane, Silkov, Antonina, Ligon, Keith L., Pomeroy, Scott L., Rivera, Miguel N., Rozenblatt-Rosen, Orit, Rusert, Jessica M., Wechsler-Reya, Robert J., Li, Xiao-Nan, Peyrl, Andreas, Gojo, Johannes, Kirchhofer, Dominik, Lötsch, Daniela, Czech, Thomas, Dorfer, Christian, Haberler, Christine, Geyeregger, Rene, Halfmann, Angela, Gawad, Charles, Easton, John, Pfister, Stefan M., Regev, Aviv, Gajjar, Amar, Orr, Brent A., Slavc, Irene, Robinson, Giles W., Bernstein, Bradley E., Suvà, Mario L., Northcott, Paul A.
Published in Nature (London) (01.08.2019)
Published in Nature (London) (01.08.2019)
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Single-Cell RNA-Seq Reveals Cellular Hierarchies and Impaired Developmental Trajectories in Pediatric Ependymoma
Gojo, Johannes, Englinger, Bernhard, Jiang, Li, Hübner, Jens M., Shaw, McKenzie L., Hack, Olivia A., Madlener, Sibylle, Kirchhofer, Dominik, Liu, Ilon, Pyrdol, Jason, Hovestadt, Volker, Mazzola, Emanuele, Mathewson, Nathan D., Trissal, Maria, Lötsch, Daniela, Dorfer, Christian, Haberler, Christine, Halfmann, Angela, Mayr, Lisa, Peyrl, Andreas, Geyeregger, Rene, Schwalm, Benjamin, Mauermann, Monica, Pajtler, Kristian W., Milde, Till, Shore, Marni E., Geduldig, Jack E., Pelton, Kristine, Czech, Thomas, Ashenberg, Orr, Wucherpfennig, Kai W., Rozenblatt-Rosen, Orit, Alexandrescu, Sanda, Ligon, Keith L., Pfister, Stefan M., Regev, Aviv, Slavc, Irene, Berger, Walter, Suvà, Mario L., Kool, Marcel, Filbin, Mariella G.
Published in Cancer cell (13.07.2020)
Published in Cancer cell (13.07.2020)
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BAF Complex Maintains Glioma Stem Cells in Pediatric H3K27M Glioma
Panditharatna, Eshini, Marques, Joana G, Wang, Tingjian, Trissal, Maria C, Liu, Ilon, Jiang, Li, Beck, Alexander, Groves, Andrew, Dharia, Neekesh V, Li, Deyao, Hoffman, Samantha E, Kugener, Guillaume, Shaw, McKenzie L, Mire, Hafsa M, Hack, Olivia A, Dempster, Joshua M, Lareau, Caleb, Dai, Lingling, Sigua, Logan H, Quezada, Michael A, Stanton, Ann-Catherine J, Wyatt, Meghan, Kalani, Zohra, Goodale, Amy, Vazquez, Francisca, Piccioni, Federica, Doench, John G, Root, David E, Anastas, Jamie N, Jones, Kristen L, Conway, Amy Saur, Stopka, Sylwia, Regan, Michael S, Liang, Yu, Seo, Hyuk-Soo, Song, Kijun, Bashyal, Puspalata, Jerome, William P, Mathewson, Nathan D, Dhe-Paganon, Sirano, Suvà, Mario L, Carcaboso, Angel M, Lavarino, Cinzia, Mora, Jaume, Nguyen, Quang-De, Ligon, Keith L, Shi, Yang, Agnihotri, Sameer, Agar, Nathalie Y R, Stegmaier, Kimberly, Stiles, Charles D, Monje, Michelle, Golub, Todd R, Qi, Jun, Filbin, Mariella G
Published in Cancer discovery (02.12.2022)
Published in Cancer discovery (02.12.2022)
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GABAergic neuronal lineage development determines clinically actionable targets in diffuse hemispheric glioma, H3G34-mutant
Liu, Ilon, Alencastro Veiga Cruzeiro, Gustavo, Bjerke, Lynn, Rogers, Rebecca F., Grabovska, Yura, Beck, Alexander, Mackay, Alan, Barron, Tara, Hack, Olivia A., Quezada, Michael A., Molinari, Valeria, Shaw, McKenzie L., Perez-Somarriba, Marta, Temelso, Sara, Raynaud, Florence, Ruddle, Ruth, Panditharatna, Eshini, Englinger, Bernhard, Mire, Hafsa M., Jiang, Li, Nascimento, Andrezza, LaBelle, Jenna, Haase, Rebecca, Rozowsky, Jacob, Neyazi, Sina, Baumgartner, Alicia-Christina, Castellani, Sophia, Hoffman, Samantha E., Cameron, Amy, Morrow, Murry, Nguyen, Quang-De, Pericoli, Giulia, Madlener, Sibylle, Mayr, Lisa, Dorfer, Christian, Geyeregger, Rene, Rota, Christopher, Ricken, Gerda, Ligon, Keith L., Alexandrescu, Sanda, Cartaxo, Rodrigo T., Lau, Benison, Uphadhyaya, Santhosh, Koschmann, Carl, Braun, Emelie, Danan-Gotthold, Miri, Hu, Lijuan, Siletti, Kimberly, Sundström, Erik, Hodge, Rebecca, Lein, Ed, Agnihotri, Sameer, Eisenstat, David D., Stapleton, Simon, King, Andrew, Bleil, Cristina, Mastronuzzi, Angela, Cole, Kristina A., Waanders, Angela J., Montero Carcaboso, Angel, Schüller, Ulrich, Hargrave, Darren, Vinci, Maria, Carceller, Fernando, Haberler, Christine, Slavc, Irene, Linnarsson, Sten, Gojo, Johannes, Monje, Michelle, Jones, Chris, Filbin, Mariella G.
Published in Cancer cell (27.08.2024)
Published in Cancer cell (27.08.2024)
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Decoupling genetics, lineages, and microenvironment in IDH-mutant gliomas by single-cell RNA-seq
Venteicher, Andrew S., Tirosh, Itay, Hebert, Christine, Yizhak, Keren, Neftel, Cyril, Filbin, Mariella G., Hovestadt, Volker, Escalante, Leah E., Shaw, McKenzie L., Rodman, Christopher, Gillespie, Shawn M., Dionne, Danielle, Luo, Christina C., Ravichandran, Hiranmayi, Mylvaganam, Ravindra, Mount, Christopher, Onozato, Maristela L., Nahed, Brian V., Wakimoto, Hiroaki, Curry, William T., Iafrate, A. John, Rivera, Miguel N., Frosch, Matthew P., Golub, Todd R., Brastianos, Priscilla K., Getz, Gad, Patel, Anoop P., Monje, Michelle, Cahill, Daniel P., Rozenblatt-Rosen, Orit, Louis, David N., Bernstein, Bradley E., Regev, Aviv, Suvà, Mario L.
Published in Science (American Association for the Advancement of Science) (31.03.2017)
Published in Science (American Association for the Advancement of Science) (31.03.2017)
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EPCO-45. CELLULAR HIERARCHIES OF ETMR ARE SHAPED BY ONCOGENIC MICRORNAS AND RECEPTOR-LIGAND INTERACTIONS
Gabler, Lisa, Beck, Alexander, Cruzeiro, Gustavo, Lambo, Sander, Englinger, Bernhard, Shaw, McKenzie L, Hack, Olivia, Chi, Susan, Alexandrescu, Sanda, Gojo, Johannes, Kool, Marcel, Hovestadt, Volker, Filbin, Mariella
Published in Neuro-oncology (Charlottesville, Va.) (10.11.2023)
Published in Neuro-oncology (Charlottesville, Va.) (10.11.2023)
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EPEN-12. COMPARING CELLULAR HIERARCHIES AND SPATIAL ARCHITECTURE ACROSS MOLECULAR SUBGROUPS OF SUPRATENTORIAL EPENDYMOMAS
Jeong, Daeun, Maass, Kendra K, Ghasemi, David R, Englinger, Bernhard, Jiang, Li, Nascimento, Andrezza, Hack, Olivia A, Shaw, McKenzie L, Pfister, Stefan M, Kool, Marcel, Gojo, Johannes, Pajtler, Kristian W, Filbin, Mariella G
Published in Neuro-oncology (Charlottesville, Va.) (12.06.2023)
Published in Neuro-oncology (Charlottesville, Va.) (12.06.2023)
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ATRT-10. SINGLE-CELL TRANSCRIPTOME ANALYSIS REVEALS CELLULAR HIERARCHIES AND THERAPEUTIC VULNERABILITIES OF ETMR
Beck, Alexander, Gabler, Lisa, Cruzeiro, Gustavo A V, Lambo, Sander, Englinger, Bernhard, Shaw, McKenzie L, Hack, Olivia A, Liu, Ilon, Junior, Carlos A O de Biagi, Haase, Rebecca D, Klenner, Marbod, Freidel, Pia, Madlener, Sibylle, Mayr, Lisa, Senfter, Daniel, Peyrl, Andreas, Slavc, Irene, Lötsch, Daniela, Dorfer, Christian, Haberler, Christine, Pfister, Stefan M, Baird, Lissa, Chi, Susan N, Alexandrescu, Sanda, Gojo, Johannes, Kool, Marcel, Hovestadt, Volker, Filbin, Mariella G
Published in Neuro-oncology (Charlottesville, Va.) (12.06.2023)
Published in Neuro-oncology (Charlottesville, Va.) (12.06.2023)
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HGG-17. SINGLE-CELL AND SPATIAL ANALYSES DECIPHER THE UNIQUE INVASIVE GROWTH PATTERN OF GLIOMATOSIS CEREBRI
Crampsie, Shauna, Liu, Ilon, Petrilli, Lucia Lisa, Mackay, Alan, Spinozzi, Giulio, Grabovska, Yura, Hack, Olivia A, Kessler, Ketty, Temelso, Sara, Carvalho, Diana Martins, Burford, Anna, Sejdiu, Drenusha, Molinari, Valeria, Shaw, McKenzie L, Mire, Hafsa M, Pericoli, Giulia, Cerimele, Alfredo, Barry, Clémentine, Cocito, Carolina, Debily, Marie-Anne, Kergrohen, Thomas, Ajlil, Yassine, Beccaria, Kévin, Varlet, Pascale, Tauziède-Espariat, Arnault, Mastronuzzi, Angela, Carai, Andrea, Giovannoni, Isabella, Rossi, Sabrina, Miele, Evelina, Grill, Jacques, Jacques, Thomas S, Greenfield, Jeffery P, Castel, David, Vinci, Maria, Filbin, Mariella G, Jones, Chris
Published in Neuro-oncology (Charlottesville, Va.) (12.06.2023)
Published in Neuro-oncology (Charlottesville, Va.) (12.06.2023)
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ETMR-17. SINGLE-CELL TRANSCRIPTOME ANALYSIS OF ETMR PATIENT SAMPLES
Hovestadt, Volker, Shaw, McKenzie L, Beck, Alexander, Lambo, Sander, Hack, Olivia A, Gojo, Johannes, Madlener, Sibylle, Mayr, Lisa, Haberler, Christine, Czech, Thomas, Hanson, Derek R, Koschmann, Carl, Jabado, Nada, Huang, Annie A, Slavc, Irene, Pfister, Stefan M, Alexandrescu, Sanda, Bernstein, Bradley E, Kool, Marcel, Filbin, Mariella G
Published in Neuro-oncology (Charlottesville, Va.) (04.12.2020)
Published in Neuro-oncology (Charlottesville, Va.) (04.12.2020)
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EPEN-21. IMPAIRED NEURONAL-GLIAL FATE SPECIFICATION IN PEDIATRIC EPENDYMOMA REVEALED BY SINGLE-CELL RNA-SEQ
Englinger, Bernhard, Gojo, Johannes, Jiang, Li, Hübner, Jens M, Shaw, McKenzie L, Hack, Olivia A, Madlener, Sibylle, Kirchhofer, Dominik, Liu, Ilon, Pyrdol, Jason, Hovestadt, Volker, Mazzola, Emanuele, Mathewson, Nathan D, Trissal, Maria, Lötsch, Daniela, Berger, Walter, Dorfer, Christian, Haberler, Christine, Halfmann, Angela, Mayr, Lisa, Peyrl, Andreas, Geyeregger, Rene, Pajtler, Kristian W, Milde, Till, Geduldig, Jack E, Pelton, Kristine, Czech, Thomas, Ashenberg, Orr, Wucherpfennig, Kai W, Rozenblatt-Rosen, Orit, Alexandrescu, Sanda, Ligon, Keith L, Pfister, Stefan M, Regev, Aviv, Slavc, Irene, Suva, Mario L, Kool, Marcel, Filbin, Mariella
Published in Neuro-oncology (Charlottesville, Va.) (04.12.2020)
Published in Neuro-oncology (Charlottesville, Va.) (04.12.2020)
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MBRS-28. SINGLE-CELL TRANSCRIPTOME ANALYSIS OF MEDULLOBLASTOMA
Hovestadt, Volker, Filbin, Mariella G, Bihannic, Laure, Shaw, McKenzie L, DeWitt, John M, Groves, Andrew, Smith, Kyle S, Hadley, Jennifer, Gajjar, Amar, Robinson, Giles W, Mayr, Lisa, Slavc, Irene, Goumnerova, Liliana, Ligon, Keith L, Suva, Mario L, Northcott, Paul A, Bernstein, Bradley E
Published in Neuro-oncology (Charlottesville, Va.) (22.06.2018)
Published in Neuro-oncology (Charlottesville, Va.) (22.06.2018)
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