Targeting a Braf/Mapk pathway rescues podocyte lipid peroxidation in CoQ-deficiency kidney disease
Sidhom, Eriene-Heidi, Kim, Choah, Kost-Alimova, Maria, Ting, May Theng, Keller, Keith, Avila-Pacheco, Julian, Watts, Andrew Jb, Vernon, Katherine A, Marshall, Jamie L, Reyes-Bricio, Estefanía, Racette, Matthew, Wieder, Nicolas, Kleiner, Giulio, Grinkevich, Elizabeth J, Chen, Fei, Weins, Astrid, Clish, Clary B, Shaw, Jillian L, Quinzii, Catarina M, Greka, Anna
Published in The Journal of clinical investigation (01.03.2021)
Published in The Journal of clinical investigation (01.03.2021)
Get full text
Journal Article
Lipid metabolism in sickness and in health: Emerging regulators of lipotoxicity
Yoon, Haejin, Shaw, Jillian L., Haigis, Marcia C., Greka, Anna
Published in Molecular cell (16.09.2021)
Published in Molecular cell (16.09.2021)
Get full text
Journal Article
Maintenance of Stem Cell Niche Integrity by a Novel Activator of Integrin Signaling
Lee, Joo Yeun, Chen, Jessica Y, Shaw, Jillian L, Chang, Karen T
Published in PLoS genetics (18.05.2016)
Published in PLoS genetics (18.05.2016)
Get full text
Journal Article
Mechanisms of Protein Trafficking and Quality Control in the Kidney and Beyond
Shaw, Jillian L, Pablo, Juan Lorenzo, Greka, Anna
Published in Annual review of physiology (10.02.2023)
Published in Annual review of physiology (10.02.2023)
Get full text
Journal Article
A Rare Kidney Disease To Cure Them All? Towards Mechanism-Based Therapies for Proteinopathies
Dvela-Levitt, Moran, Shaw, Jillian L., Greka, Anna
Published in Trends in molecular medicine (01.04.2021)
Published in Trends in molecular medicine (01.04.2021)
Get full text
Journal Article
FALCON systematically interrogates free fatty acid biology and identifies a novel mediator of lipotoxicity
Wieder, Nicolas, Fried, Juliana Coraor, Kim, Choah, Sidhom, Eriene-Heidi, Brown, Matthew R., Marshall, Jamie L., Arevalo, Carlos, Dvela-Levitt, Moran, Kost-Alimova, Maria, Sieber, Jonas, Gabriel, Katlyn R., Pacheco, Julian, Clish, Clary, Abbasi, Hamdah Shafqat, Singh, Shantanu, Rutter, Justine C., Therrien, Martine, Yoon, Haejin, Lai, Zon Weng, Baublis, Aaron, Subramanian, Renuka, Devkota, Ranjan, Small, Jonnell, Sreekanth, Vedagopuram, Han, Myeonghoon, Lim, Donghyun, Carpenter, Anne E., Flannick, Jason, Finucane, Hilary, Haigis, Marcia C., Claussnitzer, Melina, Sheu, Eric, Stevens, Beth, Wagner, Bridget K., Choudhary, Amit, Shaw, Jillian L., Pablo, Juan Lorenzo, Greka, Anna
Published in Cell metabolism (02.05.2023)
Published in Cell metabolism (02.05.2023)
Get full text
Journal Article
Protective role for kidney TREM2high macrophages in obesity- and diabetes-induced kidney injury
Subramanian, Ayshwarya, Vernon, Katherine A., Zhou, Yiming, Marshall, Jamie L., Alimova, Maria, Arevalo, Carlos, Zhang, Fan, Slyper, Michal, Waldman, Julia, Montesinos, Monica S., Dionne, Danielle, Nguyen, Lan T., Cuoco, Michael S., Dubinsky, Dan, Purnell, Jason, Keller, Keith, Sturner, Samuel H., Grinkevich, Elizabeth, Ghoshal, Ayan, Kotek, Amanda, Trivioli, Giorgio, Richoz, Nathan, Humphrey, Mary B., Darby, Isabella G., Miller, Sarah J., Xu, Yingping, Weins, Astrid, Chloe-Villani, Alexandra, Chang, Steven L., Kretzler, Matthias, Rosenblatt-Rosen, Orit, Shaw, Jillian L., Zimmerman, Kurt A., Clatworthy, Menna R., Regev, Aviv, Greka, Anna
Published in Cell reports (Cambridge) (25.06.2024)
Published in Cell reports (Cambridge) (25.06.2024)
Get full text
Journal Article
A High-Content Screen for Mucin-1-Reducing Compounds Identifies Fostamatinib as a Candidate for Rapid Repurposing for Acute Lung Injury
Kost-Alimova, Maria, Sidhom, Eriene-Heidi, Satyam, Abhigyan, Chamberlain, Brian T., Dvela-Levitt, Moran, Melanson, Michelle, Alper, Seth L., Santos, Jean, Gutierrez, Juan, Subramanian, Ayshwarya, Byrne, Patrick J., Grinkevich, Elizabeth, Reyes-Bricio, Estefanía, Kim, Choah, Clark, Abbe R., Watts, Andrew J.B., Thompson, Rebecca, Marshall, Jamie, Pablo, Juan Lorenzo, Coraor, Juliana, Roignot, Julie, Vernon, Katherine A., Keller, Keith, Campbell, Alissa, Emani, Maheswarareddy, Racette, Matthew, Bazua-Valenti, Silvana, Padovano, Valeria, Weins, Astrid, McAdoo, Stephen P., Tam, Frederick W.K., Ronco, Luciene, Wagner, Florence, Tsokos, George C., Shaw, Jillian L., Greka, Anna
Published in Cell Reports Medicine (17.11.2020)
Published in Cell Reports Medicine (17.11.2020)
Get full text
Journal Article
Web Resource
FALCON systematically interrogates free fatty acid biology and identifies a novel mediator of lipotoxicity
Wieder, Nicolas, Fried, Juliana Coraor, Kim, Choah, Sidhom, Eriene-Heidi, Brown, Matthew R, Marshall, Jamie L, Arevalo, Carlos, Dvela-Levitt, Moran, Kost-Alimova, Maria, Sieber, Jonas, Gabriel, Katlyn R, Pacheco, Julian, Clish, Clary, Abbasi, Hamdah Shafqat, Singh, Shantanu, Rutter, Justine, Therrien, Martine, Yoon, Haejin, Lai, Zon Weng, Baublis, Aaron, Subramanian, Renuka, Devkota, Ranjan, Small, Jonnell, Sreekanth, Vedagopuram, Han, Myeonghoon, Lim, Donghyun, Carpenter, Anne E, Flannick, Jason, Finucane, Hilary, Haigis, Marcia C, Claussnitzer, Melina, Sheu, Eric, Stevens, Beth, Wagner, Bridget K, Choudhary, Amit, Shaw, Jillian L, Pablo, Juan Lorenzo, Greka, Anna
Published in bioRxiv (20.02.2023)
Published in bioRxiv (20.02.2023)
Get full text
Journal Article
A High Content Screen for Mucin-1-Reducing Compounds Identifies Fostamatinib as a Candidate for Rapid Repurposing for Acute Lung Injury during the COVID-19 pandemic
Alimova, Maria, Sidhom, Eriene-Heidi, Satyam, Abhigyan, Dvela-Levitt, Moran, Melanson, Michelle, Chamberlain, Brian T, Alper, Seth L, Santos, Jean, Gutierrez, Juan, Subramanian, Ayshwarya, Grinkevich, Elizabeth, Bricio, Estefania Reyes, Kim, Choah, Clark, Abbe, Watts, Andrew, Thompson, Rebecca, Marshall, Jamie, Pablo, Juan Lorenzo, Coraor, Juliana, Roignot, Julie, Vernon, Katherine A, Keller, Keith, Campbell, Alissa, Emani, Maheswarareddy, Racette, Matthew, Bazua-Valenti, Silvana, Padovano, Valeria, Weins, Astrid, McAdoo, Stephen P, Tam, Frederick W K, Ronco, Lucienne, Wagner, Florence, Tsokos, George C, Shaw, Jillian L, Greka, Anna
Published in bioRxiv : the preprint server for biology (30.06.2020)
Published in bioRxiv : the preprint server for biology (30.06.2020)
Get more information
Journal Article
Protective role for kidney TREM2 macrophages in obesity- and diabetes-induced kidney injury
Subramanian, Ayshwarya, Vernon, Katherine A., Zhou, Yiming, Marshall, Jamie L., Alimova, Maria, Arevalo, Carlos, Zhang, Fan, Slyper, Michal, Waldman, Julia, Montesinos, Monica S., Dionne, Danielle, Nguyen, Lan T., Cuoco, Michael S., Dubinsky, Dan, Purnell, Jason, Keller, Keith, Sturner, Samuel H., Grinkevich, Elizabeth, Ghoshal, Ayan, Kotek, Amanda, Trivioli, Giorgio, Richoz, Nathan, Humphrey, Mary B., Darby, Isabella G., Miller, Sarah J., Xu, Yingping, Weins, Astrid, Chloe-Villani, Alexandra, Chang, Steven L., Kretzler, Matthias, Rosenblatt-Rosen, Orit, Shaw, Jillian L., Zimmerman, Kurt A., Clatworthy, Menna R., Regev, Aviv, Greka, Anna
Published in Cell reports (Cambridge) (25.06.2024)
Published in Cell reports (Cambridge) (25.06.2024)
Get full text
Journal Article
Protective role for kidney TREM2 high macrophages in obesity- and diabetes-induced kidney injury
Subramanian, Ayshwarya, Vernon, Katherine A, Zhou, Yiming, Marshall, Jamie L, Alimova, Maria, Arevalo, Carlos, Zhang, Fan, Slyper, Michal, Waldman, Julia, Montesinos, Monica S, Dionne, Danielle, Nguyen, Lan T, Cuoco, Michael S, Dubinsky, Dan, Purnell, Jason, Keller, Keith, Sturner, Samuel H, Grinkevich, Elizabeth, Ghoshal, Ayan, Kotek, Amanda, Trivioli, Giorgio, Richoz, Nathan, Humphrey, Mary B, Darby, Isabella G, Miller, Sarah J, Xu, Yingping, Weins, Astrid, Chloe-Villani, Alexandra, Chang, Steven L, Kretzler, Matthias, Rosenblatt-Rosen, Orit, Shaw, Jillian L, Zimmerman, Kurt A, Clatworthy, Menna R, Regev, Aviv, Greka, Anna
Published in Cell reports (Cambridge) (25.06.2024)
Get full text
Published in Cell reports (Cambridge) (25.06.2024)
Journal Article
Obesity-instructed TREM2high macrophages identified by comparative analysis of diabetic mouse and human kidney at single cell resolution
Subramanian, Ayshwarya, Vernon, Katherine, Zhou, Yiming, Marshall, Jamie L, Alimova, Maria, Zhang, Fan, Slyper, Michal, Waldman, Julia, Montesinos, Monica S, Dionne, Danielle, Nguyen, Lan T, Cuoco, Michael S, Dubinsky, Dan, Purnell, Jason, Heller, Keith, Sturner, Samuel H, Grinkevich, Elizabeth, Ghoshal, Ayan, Weins, Astrid, Villani, Alexandra-Chloe, Chang, Steven L, Rosenblatt-Rosen, Orit, Shaw, Jillian L, Regev, Aviv, Greka, Anna
Published in bioRxiv (30.05.2021)
Published in bioRxiv (30.05.2021)
Get full text
Paper