TORC1 inhibition enhances immune function and reduces infections in the elderly
Mannick, Joan B, Morris, Melody, Hockey, Hans-Ulrich P, Roma, Guglielmo, Beibel, Martin, Kulmatycki, Kenneth, Watkins, Mollie, Shavlakadze, Tea, Zhou, Weihua, Quinn, Dean, Glass, David J, Klickstein, Lloyd B
Published in Science translational medicine (11.07.2018)
Published in Science translational medicine (11.07.2018)
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Journal Article
Age-Related Gene Expression Signature in Rats Demonstrate Early, Late, and Linear Transcriptional Changes from Multiple Tissues
Shavlakadze, Tea, Morris, Melody, Fang, Jian, Wang, Sharon X., Zhu, Jiang, Zhou, Weihua, Tse, Herman W., Mondragon-Gonzalez, Ricardo, Roma, Guglielmo, Glass, David J.
Published in Cell reports (Cambridge) (17.09.2019)
Published in Cell reports (Cambridge) (17.09.2019)
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Journal Article
Differential thiol oxidation of the signaling proteins Akt, PTEN or PP2A determines whether Akt phosphorylation is enhanced or inhibited by oxidative stress in C2C12 myotubes derived from skeletal muscle
Tan, Pearl Lin, Shavlakadze, Tea, Grounds, Miranda D., Arthur, Peter G.
Published in The international journal of biochemistry & cell biology (01.05.2015)
Published in The international journal of biochemistry & cell biology (01.05.2015)
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Journal Article
High mTORC1 signaling is maintained, while protein degradation pathways are perturbed in old murine skeletal muscles in the fasted state
White, Zoe, White, Robert B., McMahon, Christopher, Grounds, Miranda D., Shavlakadze, Tea
Published in The international journal of biochemistry & cell biology (01.09.2016)
Published in The international journal of biochemistry & cell biology (01.09.2016)
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Journal Article
Targeting macrophages rescues age‐related immune deficiencies in C57BL/6J geriatric mice
Jackaman, Connie, Radley‐Crabb, Hannah G., Soffe, Zoe, Shavlakadze, Tea, Grounds, Miranda D., Nelson, Delia J.
Published in Aging cell (01.06.2013)
Published in Aging cell (01.06.2013)
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Journal Article
Voluntary resistance wheel exercise from mid-life prevents sarcopenia and increases markers of mitochondrial function and autophagy in muscles of old male and female C57BL/6J mice
White, Zoe, Terrill, Jessica, White, Robert B, McMahon, Christopher, Sheard, Phillip, Grounds, Miranda D, Shavlakadze, Tea
Published in Skeletal muscle (13.12.2016)
Published in Skeletal muscle (13.12.2016)
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Journal Article
IGF1 stimulates greater muscle hypertrophy in the absence of myostatin in male mice
Hennebry, Alexander, Oldham, Jenny, Shavlakadze, Tea, Grounds, Miranda D, Sheard, Philip, Fiorotto, Marta L, Falconer, Shelley, Smith, Heather K, Berry, Carole, Jeanplong, Ferenc, Bracegirdle, Jeremy, Matthews, Kenneth, Nicholas, Gina, Senna-Salerno, Mônica, Watson, Trevor, McMahon, Christopher D
Published in Journal of endocrinology (01.08.2017)
Published in Journal of endocrinology (01.08.2017)
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Journal Article
A Neurogenic Perspective of Sarcopenia: Time Course Study of Sciatic Nerves From Aging Mice
Krishnan, Vidya S., White, Zoe, McMahon, Chris D., Hodgetts, Stuart I., Fitzgerald, Melinda, Shavlakadze, Tea, Harvey, Alan R., Grounds, Miranda D.
Published in Journal of neuropathology and experimental neurology (01.05.2016)
Published in Journal of neuropathology and experimental neurology (01.05.2016)
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Journal Article
Age-related gene expression signatures from limb skeletal muscles and the diaphragm in mice and rats reveal common and species-specific changes
Shavlakadze, Tea, Xiong, Kun, Mishra, Shawn, McEwen, Corissa, Gadi, Abhilash, Wakai, Matthew, Salmon, Hunter, Stec, Michael J, Negron, Nicole, Ni, Min, Wei, Yi, Atwal, Gurinder S, Bai, Yu, Glass, David J
Published in Skeletal muscle (12.07.2023)
Published in Skeletal muscle (12.07.2023)
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Journal Article
Quantitative assessment of muscle damage in the mdx mouse model of Duchenne muscular dystrophy using polarization-sensitive optical coherence tomography
Yang, Xiaojie, Chin, Lixin, Klyen, Blake R, Shavlakadze, Tea, McLaughlin, Robert A, Grounds, Miranda D, Sampson, David D
Published in Journal of applied physiology (1985) (01.11.2013)
Published in Journal of applied physiology (1985) (01.11.2013)
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Journal Article
Partial Inhibition of mTORC1 in Aged Rats Counteracts the Decline in Muscle Mass and Reverses Molecular Signaling Associated with Sarcopenia
Joseph, Giselle A., Wang, Sharon X., Jacobs, Cody E., Zhou, Weihua, Kimble, Garrett C., Tse, Herman W., Eash, John K., Shavlakadze, Tea, Glass, David J.
Published in Molecular and cellular biology (01.10.2019)
Published in Molecular and cellular biology (01.10.2019)
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Journal Article
GDF11 Increases with Age and Inhibits Skeletal Muscle Regeneration
Egerman, Marc A., Cadena, Samuel M., Gilbert, Jason A., Meyer, Angelika, Nelson, Hallie N., Swalley, Susanne E., Mallozzi, Carolyn, Jacobi, Carsten, Jennings, Lori L., Clay, Ieuan, Laurent, Gaëlle, Ma, Shenglin, Brachat, Sophie, Lach-Trifilieff, Estelle, Shavlakadze, Tea, Trendelenburg, Anne-Ulrike, Brack, Andrew S., Glass, David J.
Published in Cell metabolism (07.07.2015)
Published in Cell metabolism (07.07.2015)
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Journal Article
Hallmarks of ageing in human skeletal muscle and implications for understanding the pathophysiology of sarcopenia in women and men
Granic, Antoneta, Suetterlin, Karen, Shavlakadze, Tea, Grounds, Miranda D, Sayer, Avan A
Published in Clinical science (1979) (29.11.2023)
Published in Clinical science (1979) (29.11.2023)
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Journal Article
Molecular analyses provide insight into mechanisms underlying sarcopenia and myofibre denervation in old skeletal muscles of mice
Barns, Mitchell, Gondro, Cedric, Tellam, Ross L., Radley-Crabb, Hannah G., Grounds, Miranda D., Shavlakadze, Tea
Published in The international journal of biochemistry & cell biology (01.08.2014)
Published in The international journal of biochemistry & cell biology (01.08.2014)
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Journal Article
New horizons in the pathogenesis, diagnosis and management of sarcopenia
Sayer, Avan Aihie, Robinson, Sian M, Patel, Harnish P, Shavlakadze, Tea, Cooper, Cyrus, Grounds, Miranda D
Published in Age and ageing (01.03.2013)
Published in Age and ageing (01.03.2013)
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Journal Article
Lipid Accumulation in Dysferlin-Deficient Muscles
Grounds, Miranda D, Terrill, Jessica R, Radley-Crabb, Hannah G, Robertson, Terry, Papadimitriou, John, Spuler, Simone, Shavlakadze, Tea
Published in The American journal of pathology (01.06.2014)
Published in The American journal of pathology (01.06.2014)
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Journal Article
Short-term Low-Dose mTORC1 Inhibition in Aged Rats Counter-Regulates Age-Related Gene Changes and Blocks Age-Related Kidney Pathology
Shavlakadze, Tea, Zhu, Jiang, Wang, Sharon, Zhou, Weihua, Morin, Bret, Egerman, Marc A, Fan, Lin, Wang, Yanqun, Iartchouk, Oleg, Meyer, Angelika, Valdez, Reginald A, Mannick, Joan B, Klickstein, Lloyd B, Glass, David J
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (14.06.2018)
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (14.06.2018)
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Journal Article
The Activin/FLRG Pathway Associates with Poor COVID-19 Outcomes in Hospitalized Patients
McAleavy, Megan, Zhang, Qian, Ehmann, Peter J., Xu, Jianing, Wipperman, Matthew F., Ajithdoss, Dharani, Pan, Li, Wakai, Matthew, Simonson, Raphael, Gadi, Abhilash, Oyejide, Adelekan, Hamon, Sara C., Boyapati, Anita, Morton, Lori G., Shavlakadze, Tea, Kyratsous, Christos A., Glass, David J.
Published in Molecular and cellular biology (20.01.2022)
Published in Molecular and cellular biology (20.01.2022)
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