Malaria parasite DNA-harbouring vesicles activate cytosolic immune sensors
Sisquella, Xavier, Ofir-Birin, Yifat, Pimentel, Matthew A., Cheng, Lesley, Abou Karam, Paula, Sampaio, Natália G., Penington, Jocelyn Sietsma, Connolly, Dympna, Giladi, Tal, Scicluna, Benjamin J., Sharples, Robyn A., Waltmann, Andreea, Avni, Dror, Schwartz, Eli, Schofield, Louis, Porat, Ziv, Hansen, Diana S., Papenfuss, Anthony T., Eriksson, Emily M., Gerlic, Motti, Hill, Andrew F., Bowie, Andrew G., Regev-Rudzki, Neta
Published in Nature communications (07.12.2017)
Published in Nature communications (07.12.2017)
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Journal Article
Differential modulation of Alzheimer's disease amyloid beta-peptide accumulation by diverse classes of metal ligands
Caragounis, Aphrodite, Du, Tai, Filiz, Gulay, Laughton, Katrina M, Volitakis, Irene, Sharples, Robyn A, Cherny, Robert A, Masters, Colin L, Drew, Simon C, Hill, Andrew F, Li, Qiao-Xin, Crouch, Peter J, Barnham, Kevin J, White, Anthony R
Published in Biochemical journal (01.11.2007)
Published in Biochemical journal (01.11.2007)
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Journal Article
BRAFV600 inhibition alters the microRNA cargo in the vesicular secretome of malignant melanoma cells
Lunavat, Taral R., Cheng, Lesley, Einarsdottir, Berglind O., Bagge, Roger Olofsson, Muralidharan, Somsundar Veppil, Sharples, Robyn A., Lässer, Cecilia, Gho, Yong Song, Hill, Andrew F., Nilsson, Jonas A., Lötvall, Jan
Published in Proceedings of the National Academy of Sciences - PNAS (18.07.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (18.07.2017)
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Journal Article
Small RNA deep sequencing discriminates subsets of extracellular vesicles released by melanoma cells - Evidence of unique microRNA cargos
Lunavat, Taral R, Cheng, Lesley, Kim, Dae-Kyum, Bhadury, Joydeep, Jang, Su Chul, Lässer, Cecilia, Sharples, Robyn A, López, Marcela Dávila, Nilsson, Jonas, Gho, Yong Song, Hill, Andrew F, Lötvall, Jan
Published in RNA biology (2015)
Published in RNA biology (2015)
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Journal Article
Inhibition of γ-secretase causes increased secretion of amyloid precursor protein C-terminal fragments in association with exosomes
Sharples, Robyn A, Vella, Laura J, Nisbet, Rebecca M, Naylor, Ryan, Perez, Keyla, Barnham, Kevin J, Masters, Colin L, Hill, Andrew F
Published in The FASEB journal (01.05.2008)
Published in The FASEB journal (01.05.2008)
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Journal Article
Melittin peptides exhibit different activity on different cells and model membranes
Jamasbi, Elaheh, Batinovic, Steven, Sharples, Robyn A, Sani, Marc-Antoine, Robins-Browne, Roy Michael, Wade, John D, Separovic, Frances, Hossain, Mohammed Akhter
Published in Amino acids (01.12.2014)
Published in Amino acids (01.12.2014)
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Journal Article
Defining the purity of exosomes required for diagnostic profiling of small RNA suitable for biomarker discovery
Quek, Camelia, Bellingham, Shayne A., Jung, Chol-Hee, Scicluna, Benjamin J., Shambrook, Mitch C., Sharples, Robyn A., Cheng, Lesley, Hill, Andrew F.
Published in RNA biology (01.02.2017)
Published in RNA biology (01.02.2017)
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Journal Article
Selective Intracellular Release of Copper and Zinc Ions from Bis(thiosemicarbazonato) Complexes Reduces Levels of Alzheimer Disease Amyloid-β Peptide
Donnelly, Paul S., Caragounis, Aphrodite, Du, Tai, Laughton, Katrina M., Volitakis, Irene, Cherny, Robert A., Sharples, Robyn A., Hill, Andrew F., Li, Qiao-Xin, Masters, Colin L., Barnham, Kevin J., White, Anthony R.
Published in The Journal of biological chemistry (22.02.2008)
Published in The Journal of biological chemistry (22.02.2008)
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Journal Article
Degradation of the Alzheimer Disease Amyloid β-Peptide by Metal-dependent Up-regulation of Metalloprotease Activity
White, Anthony R., Du, Tai, Laughton, Katrina M., Volitakis, Irene, Sharples, Robyn A., Xilinas, Michel E., Hoke, David E., Holsinger, R. M. Damian, Evin, Geneviève, Cherny, Robert A., Hill, Andrew F., Barnham, Kevin J., Li, Qiao-Xin, Bush, Ashley I., Masters, Colin L.
Published in The Journal of biological chemistry (30.06.2006)
Published in The Journal of biological chemistry (30.06.2006)
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Journal Article
Gene dysregulation is restored in the Parkinson's disease MPTP neurotoxic mice model upon treatment of the therapeutic drug Cu(II)(atsm)
Cheng, Lesley, Quek, Camelia Y J, Hung, Lin W, Sharples, Robyn A, Sherratt, Nicki A, Barnham, Kevin J, Hill, Andrew F
Published in Scientific reports (01.03.2016)
Published in Scientific reports (01.03.2016)
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Journal Article
Gene dysregulation is restored in the Parkinson’s disease MPTP neurotoxic mice model upon treatment of the therapeutic drug CuII(atsm)
Cheng, Lesley, Quek, Camelia Y. J., Hung, Lin W., Sharples, Robyn A., Sherratt, Nicki A., Barnham, Kevin J., Hill, Andrew F.
Published in Scientific reports (01.03.2016)
Published in Scientific reports (01.03.2016)
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Journal Article
Site of fluorescent label modifies interaction of melittin with live cells and model membranes
Jamasbi, Elaheh, Ciccotosto, Giuseppe D., Tailhades, Julien, Robins-Browne, Roy M., Ugalde, Cathryn L., Sharples, Robyn A., Patil, Nitin, Wade, John D., Hossain, Mohammed Akhter, Separovic, Frances
Published in Biochimica et biophysica acta (01.10.2015)
Published in Biochimica et biophysica acta (01.10.2015)
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Journal Article
BRAF V600 inhibition alters the microRNA cargo in the vesicular secretome of malignant melanoma cells
Lunavat, Taral R, Cheng, Lesley, Einarsdottir, Berglind O, Olofsson Bagge, Roger, Veppil Muralidharan, Somsundar, Sharples, Robyn A, Lässer, Cecilia, Gho, Yong Song, Hill, Andrew F, Nilsson, Jonas A, Lötvall, Jan
Published in Proceedings of the National Academy of Sciences - PNAS (18.07.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (18.07.2017)
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Journal Article
Dopamine promotes alpha-synuclein aggregation into SDS-resistant soluble oligomers via a distinct folding pathway
Cappai, Roberto, Leck, Su-Ling, Tew, Deborah J, Williamson, Nicholas A, Smith, David P, Galatis, Denise, Sharples, Robyn A, Curtain, Cyril C, Ali, Feda' E, Cherny, Robert A, Culvenor, Janetta G, Bottomley, Stephen P, Masters, Colin L, Barnham, Kevin J, Hill, Andrew F
Published in The FASEB journal (01.08.2005)
Published in The FASEB journal (01.08.2005)
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Journal Article
Mouse-adapted sporadic human Creutzfeldt–Jakob disease prions propagate in cell culture
Lawson, Victoria A., Vella, Laura J., Stewart, James D., Sharples, Robyn A., Klemm, Helen, Machalek, Dorothy M., Masters, Colin L., Cappai, Roberto, Collins, Steven J., Hill, Andrew F.
Published in The international journal of biochemistry & cell biology (2008)
Published in The international journal of biochemistry & cell biology (2008)
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Journal Article
Activation of epidermal growth factor receptor by metal-ligand complexes decreases levels of extracellular amyloid beta peptide
Price, Katherine A., Filiz, Gulay, Caragounis, Aphrodite, Du, Tai, Laughton, Katrina M., Masters, Colin L., Sharples, Robyn A., Hill, Andrew F., Li, Qiao-Xin, Donnelly, Paul S., Barnham, Kevin J., Crouch, Peter J., White, Anthony R.
Published in The international journal of biochemistry & cell biology (2008)
Published in The international journal of biochemistry & cell biology (2008)
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Journal Article
Aspartyl Protease Inhibitor Pepstatin Binds to the Presenilins of Alzheimer's Disease
Evin, Geneviève, Sharples, Robyn A, Weidemann, Andreas, Reinhard, Friedrich B. M, Carbone, Vincenzo, Culvenor, Janetta G, Holsinger, R. M. Damian, Sernee, M. Fleur, Beyreuther, Konrad, Masters, Colin L
Published in Biochemistry (Easton) (17.07.2001)
Published in Biochemistry (Easton) (17.07.2001)
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