K15 Protein of Kaposi’s Sarcoma-Associated Herpesvirus Is Latently Expressed and Binds to HAX-1, a Protein with Antiapoptotic Function
Sharp, Tyson V, Wang, Hsei-Wei, Koumi, Andrew, Hollyman, Daniel, Endo, Yoshio, Ye, Hongtao, Du, Ming-Qing, Boshoff, Chris
Published in Journal of Virology (01.01.2002)
Published in Journal of Virology (01.01.2002)
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Journal Article
Oxidative stress downstream of mTORC1 but not AKT causes a proliferative defect in cancer cells resistant to PI3K inhibition
Dermit, M, Casado, P, Rajeeve, V, Wilkes, E H, Foxler, D E, Campbell, H, Critchlow, S, Sharp, T V, Gribben, J G, Unwin, R, Cutillas, P R
Published in Oncogene (11.05.2017)
Published in Oncogene (11.05.2017)
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Journal Article
The Vaccinia Virus E3L Gene Product Interacts with both the Regulatory and the Substrate Binding Regions of PKR: Implications for PKR Autoregulation
Sharp, T.V., Moonan, F., Romashko, A., Joshi, B., Barber, G.N., Jagus, R.
Published in Virology (New York, N.Y.) (25.10.1998)
Published in Virology (New York, N.Y.) (25.10.1998)
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Journal Article
Characterization of an anti-apoptotic glycoprotein encoded by Kaposi's sarcoma-associated herpesvirus which resembles a spliced variant of human survivin
Wang, Hsei-Wei, Sharp, Tyson V., Koumi, Andrew, Koentges, Georgy, Boshoff, Chris
Published in The EMBO journal (03.06.2002)
Published in The EMBO journal (03.06.2002)
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Journal Article
The La antigen inhibits the activation of the interferon-inducible protein kinase PKR by sequestering and unwinding double-stranded RNA
QIURONG XIAO, SHARP, T. V, JEFFREY, I. W, JAMES, M. C, PRUIJN, G. J. M, VAN VENROOIJ, W. J, CLEMENS, M. J
Published in Nucleic acids research (11.07.1994)
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Published in Nucleic acids research (11.07.1994)
Journal Article
Regulation of the interferon-inducible eIF-2α protein kinase by small RNAs
Clemens, M.J., Laing, K.G., Jeffrey, I.W., Schofield, A., Sharp, T.V., Elia, A., Matys, V., James, M.C., Tilleray, V.J.
Published in Biochimie (1994)
Published in Biochimie (1994)
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Journal Article
Reversal of the double‐stranded‐RNA‐induced inhibition of protein synthesis by a catalytically inactive mutant of the protein kinase PKR
SHARP, Tyson V., XIAO, Qiurong, JEFFREY, Ian, GEWERT, Dirk R., CLEMENS, Michael J.
Published in European journal of biochemistry (15.06.1993)
Published in European journal of biochemistry (15.06.1993)
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Journal Article
Homologous Regions of the α Subunit of Eukaryotic Translational Initiation Factor 2 (eIF2α) and the Vaccinia Virus K3L Gene Product Interact with the Same Domain within the dsRNA‐Activated Protein Kinase (PKR)
Sharp, Tyson V., Witzel, J. Eric, Jagus, Rosemary
Published in European journal of biochemistry (15.11.1997)
Published in European journal of biochemistry (15.11.1997)
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Journal Article
Functional expression of secreted proteins from a bicistronic retroviral cassette based on foot-and-mouth disease virus 2A can be position dependent
Rothwell, Dominic G, Crossley, Rachel, Bridgeman, John S, Sheard, Victoria, Zhang, Yining, Sharp, Tyson V, Hawkins, Robert E, Gilham, David E, McKay, Tristan R
Published in Human gene therapy (01.11.2010)
Published in Human gene therapy (01.11.2010)
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Journal Article
Regulation of the interferon-inducible protein kinase PKR and (2'-5')oligo(adenylate) synthetase by a catalytically inactive PKR mutant through competition for double-stranded RNA binding
Sharp, T V, Xiao, Q, Justesen, J, Gewert, D R, Clemens, M J
Published in European journal of biochemistry (15.05.1995)
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Published in European journal of biochemistry (15.05.1995)
Journal Article
LIM domains-containing protein 1 (LIMD1), a tumor suppressor encoded at chromosome 3p2l.3, binds pRB and represses E2F-driven transcription
Sharp, TV, Munoz, F, Bourboulia, D, Presneau, N, Darai, E, Wang, HW, Cannon, M, Butcher, DN, Nicholson, AG, Klein, G
Published in Proceedings of the National Academy of Sciences - PNAS (23.11.2004)
Published in Proceedings of the National Academy of Sciences - PNAS (23.11.2004)
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Journal Article
LIM Domains-Containing Protein 1 (LIMD1), a Tumor Suppressor Encoded at Chromosome 3p21.3, Binds pRB and Represses E2F-Driven Transcription
Sharp, Tyson V., Munoz, Fernando, Bourboulia, Dimitra, Presneau, Nadege, Darai, Eva, Wang, Hsei-Wei, Cannon, Mark, Butcher, David N., Nicholson, Andrew G., Klein, George, Imreh, Stephan, Boshoff, Chris
Published in Proceedings of the National Academy of Sciences - PNAS (23.11.2004)
Published in Proceedings of the National Academy of Sciences - PNAS (23.11.2004)
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Journal Article
Comparative analysis of the regulation of the interferon-inducible protein kinase PKR by Epstein-Barr virus RNAs EBER-1 and EBER-2 and adenovirus VAI RNA
Sharp, T V, Schwemmle, M, Jeffrey, I, Laing, K, Mellor, H, Proud, C G, Hilse, K, Clemens, M J
Published in Nucleic acids research (25.09.1993)
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Published in Nucleic acids research (25.09.1993)
Journal Article
Comparative analysis of the regulation of the inteferon-inducible protein kinase PKR by Epstein-Barr virus RNAs EBER-1 and EBER-2 and adenovirus VA I RNA
SHARP, T. V, SCHWEMMLE, M, JEFFREY, I, LAING, K, MELLOR, H, PROUD, C. G, HILSE, K, CLEMENS, M. J
Published in Nucleic acids research (1993)
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Published in Nucleic acids research (1993)
Journal Article
Comparative analysis of the regulation of the interferon-inducible protein kinase PKR by Epstein-Barr virus RNAs EBER-1 and EBER-2 and adenovirus VA sub(I) RNA
Sharp, T V, Schwemmle, M, Jeffrey, I, Laing, K, Mellor, H, Proud, C G, Hilse, K, Clemens, MJ
Published in Nucleic acids research (01.01.1993)
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Published in Nucleic acids research (01.01.1993)
Journal Article