Heterogeneity of meningeal B cells reveals a lymphopoietic niche at the CNS borders
Brioschi, Simone, Wang, Wei-Le, Peng, Vincent, Wang, Meng, Shchukina, Irina, Greenberg, Zev J, Bando, Jennifer K, Jaeger, Natalia, Czepielewski, Rafael S, Swain, Amanda, Mogilenko, Denis A, Beatty, Wandy L, Bayguinov, Peter, Fitzpatrick, James A J, Schuettpelz, Laura G, Fronick, Catrina C, Smirnov, Igor, Kipnis, Jonathan, Shapiro, Virginia S, Wu, Gregory F, Gilfillan, Susan, Cella, Marina, Artyomov, Maxim N, Kleinstein, Steven H, Colonna, Marco
Published in Science (American Association for the Advancement of Science) (23.07.2021)
Published in Science (American Association for the Advancement of Science) (23.07.2021)
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The Chemoattractant Receptor Ebi2 Drives Intranodal Naive CD4+ T Cell Peripheralization to Promote Effective Adaptive Immunity
Baptista, Antonio P., Gola, Anita, Huang, Yuefeng, Milanez-Almeida, Pedro, Torabi-Parizi, Parizad, Urban, Joseph F., Shapiro, Virginia S., Gerner, Michael Y., Germain, Ronald N.
Published in Immunity (Cambridge, Mass.) (21.05.2019)
Published in Immunity (Cambridge, Mass.) (21.05.2019)
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Uncoupling of macrophage inflammation from self-renewal modulates host recovery from respiratory viral infection
Zhu, Bibo, Wu, Yue, Huang, Su, Zhang, Ruixuan, Son, Young Min, Li, Chaofan, Cheon, In Su, Gao, Xiaochen, Wang, Min, Chen, Yao, Zhou, Xian, Nguyen, Quynh, Phan, Anthony T., Behl, Supriya, Taketo, M. Mark, Mack, Matthias, Shapiro, Virginia S., Zeng, Hu, Ebihara, Hideki, Mullon, John J., Edell, Eric S., Reisenauer, Janani S., Demirel, Nadir, Kern, Ryan M., Chakraborty, Rana, Cui, Weiguo, Kaplan, Mark H., Zhou, Xiaobo, Goldrath, Ananda W., Sun, Jie
Published in Immunity (Cambridge, Mass.) (08.06.2021)
Published in Immunity (Cambridge, Mass.) (08.06.2021)
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Coactosin-like 1 antagonizes cofilin to promote lamellipodial protrusion at the immune synapse
Kim, Joanna, Shapiro, Michael J, Bamidele, Adebowale O, Gurel, Pinar, Thapa, Puspa, Higgs, Henry N, Hedin, Karen E, Shapiro, Virginia S, Billadeau, Daniel D
Published in PloS one (13.01.2014)
Published in PloS one (13.01.2014)
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Locally Produced Complement Fragments C5a and C3a Provide Both Costimulatory and Survival Signals to Naive CD4+ T Cells
Strainic, Michael G., Liu, Jinbo, Huang, Danping, An, Fengqi, Lalli, Peter N., Muqim, Nasima, Shapiro, Virginia S., Dubyak, George R., Heeger, Peter S., Medof, M. Edward
Published in Immunity (Cambridge, Mass.) (01.03.2008)
Published in Immunity (Cambridge, Mass.) (01.03.2008)
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Increased expression of BubR1 protects against aneuploidy and cancer and extends healthy lifespan
Baker, Darren J., Dawlaty, Meelad M., Wijshake, Tobias, Jeganathan, Karthik B., Malureanu, Liviu, van Ree, Janine H., Crespo-Diaz, Ruben, Reyes, Santiago, Seaburg, Lauren, Shapiro, Virginia, Behfar, Atta, Terzic, Andre, van de Sluis, Bart, van Deursen, Jan M.
Published in Nature cell biology (01.01.2013)
Published in Nature cell biology (01.01.2013)
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Journal Article
Cyclin A2 is an RNA binding protein that controls Mre11 mRNA translation
Kanakkanthara, Arun, Jeganathan, Karthik B, Limzerwala, Jazeel F, Baker, Darren J, Hamada, Masakazu, Nam, Hyun-Ja, van Deursen, Willemijn H, Hamada, Naomi, Naylor, Ryan M, Becker, Nicole A, Davies, Brian A, van Ree, Janine H, Mer, Georges, Shapiro, Virginia S, Maher, 3rd, L James, Katzmann, David J, van Deursen, Jan M
Published in Science (American Association for the Advancement of Science) (30.09.2016)
Published in Science (American Association for the Advancement of Science) (30.09.2016)
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Journal Article
Inactivation of Brca2 Promotes Trp53-Associated but Inhibits KrasG12D-Dependent Pancreatic Cancer Development in Mice
Rowley, Matthew, Ohashi, Akihiro, Mondal, Gourish, Mills, Lisa, Yang, Lin, Zhang, Lizhi, Sundsbak, Rhianna, Shapiro, Virginia, Muders, Michael H, Smyrk, Thomas, Couch, Fergus J
Published in Gastroenterology (New York, N.Y. 1943) (01.04.2011)
Published in Gastroenterology (New York, N.Y. 1943) (01.04.2011)
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Adult hematopoietic stem cells require NKAP for maintenance and survival
Pajerowski, Anthony G., Shapiro, Michael J., Gwin, Kimberly, Sundsbak, Rhianna, Nelson-Holte, Molly, Medina, Kay, Shapiro, Virginia Smith
Published in Blood (14.10.2010)
Published in Blood (14.10.2010)
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The nutrient-sensing Rag-GTPase complex in B cells controls humoral immunity via TFEB/TFE3-dependent mitochondrial fitness
Zhu, Xingxing, Wu, Yue, Li, Yanfeng, Zhou, Xian, Watzlawik, Jens O., Chen, Yin Maggie, Raybuck, Ariel L., Billadeau, Daniel D., Shapiro, Virginia Smith, Springer, Wolfdieter, Sun, Jie, Boothby, Mark R., Zeng, Hu
Published in Nature communications (23.11.2024)
Published in Nature communications (23.11.2024)
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Journal Article
Histone deacetylase 3 is required for iNKT cell development
Thapa, Puspa, Romero Arocha, Sinibaldo, Chung, Ji Young, Sant’Angelo, Derek B., Shapiro, Virginia Smith
Published in Scientific reports (19.07.2017)
Published in Scientific reports (19.07.2017)
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Journal Article
The mitochondrial iron transporter ABCB7 is required for B cell development, proliferation, and class switch recombination in mice
Lehrke, Michael Jonathan, Shapiro, Michael Jeremy, Rajcula, Matthew J, Kennedy, Madeleine M, McCue, Shaylene A, Medina, Kay L, Shapiro, Virginia Smith
Published in eLife (11.11.2021)
Published in eLife (11.11.2021)
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Identification and characterization of the antigen recognized by the germ cell mAb TRA98 using a human comprehensive wet protein array
Fukuda, Eriko, Tanaka, Hiromitsu, Yamaguchi, Kei, Takasaka, Mieko, Kawamura, Yoshifumi, Okuda, Hidenobu, Isotani, Ayako, Ikawa, Masahito, Shapiro, Virginia Smith, Tsuchida, Junji, Okada, Yuki, Tsujimura, Akira, Miyagawa, Yasushi, Fukuhara, Shinichiro, Kawakami, Yoshitaka, Wada, Morimasa, Nishimune, Yoshitake, Goshima, Naoki
Published in Genes to cells : devoted to molecular & cellular mechanisms (01.03.2021)
Published in Genes to cells : devoted to molecular & cellular mechanisms (01.03.2021)
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Journal Article
Histone deacetylase 3 represses cholesterol efflux during CD4 + T-cell activation
Wilfahrt, Drew, Philips, Rachael L, Lama, Jyoti, Kizerwetter, Monika, Shapiro, Michael Jeremy, McCue, Shaylene A, Kennedy, Madeleine M, Rajcula, Matthew J, Zeng, Hu, Shapiro, Virginia Smith
Published in eLife (02.12.2021)
Published in eLife (02.12.2021)
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Journal Article
HDAC3 restrains CD8-lineage genes to maintain a bi-potential state in CD4 + CD8 + thymocytes for CD4-lineage commitment
Philips, Rachael Laura, Lee, Jeong-Heon, Gaonkar, Krutika, Chanana, Pritha, Chung, Ji Young, Romero Arocha, Sinibaldo R, Schwab, Aaron, Ordog, Tamas, Shapiro, Virginia Smith
Published in eLife (18.01.2019)
Published in eLife (18.01.2019)
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Journal Article
The protein tyrosine phosphatase PTPN4/PTP-MEG1, an enzyme capable of dephosphorylating the TCR ITAMs and regulating NF-κB, is dispensable for T cell development and/or T cell effector functions
Young, Jennifer A., Becker, Amy M., Medeiros, Jennifer J., Shapiro, Virginia S., Wang, Andrew, Farrar, J. David, Quill, Timothy A., van Huijsduijnen, Rob Hooft, van Oers, Nicolai S.C.
Published in Molecular immunology (01.08.2008)
Published in Molecular immunology (01.08.2008)
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