LRRC15+ myofibroblasts dictate the stromal setpoint to suppress tumour immunity
Krishnamurty, Akshay T., Shyer, Justin A., Thai, Minh, Gandham, Vineela, Buechler, Matthew B., Yang, Yeqing Angela, Pradhan, Rachana N., Wang, Amber W., Sanchez, Patricia L., Qu, Yan, Breart, Beatrice, Chalouni, Cécile, Dunlap, Debra, Ziai, James, Elstrott, Justin, Zacharias, Neelie, Mao, Weiguang, Rowntree, Rebecca K., Sadowsky, Jack, Lewis, Gail D., Pillow, Thomas H., Nabet, Barzin Y., Banchereau, Romain, Tam, Lucinda, Caothien, Roger, Bacarro, Natasha, Roose-Girma, Merone, Modrusan, Zora, Mariathasan, Sanjeev, Müller, Sören, Turley, Shannon J.
Published in Nature (London) (03.11.2022)
Published in Nature (London) (03.11.2022)
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Podoplanin-Rich Stromal Networks Induce Dendritic Cell Motility via Activation of the C-type Lectin Receptor CLEC-2
Acton, Sophie E., Astarita, Jillian L., Malhotra, Deepali, Lukacs-Kornek, Veronika, Franz, Bettina, Hess, Paul R., Jakus, Zoltan, Kuligowski, Michael, Fletcher, Anne L., Elpek, Kutlu G., Bellemare-Pelletier, Angelique, Sceats, Lindsay, Reynoso, Erika D., Gonzalez, Santiago F., Graham, Daniel B., Chang, Jonathan, Peters, Anneli, Woodruff, Matthew, Kim, Young-A., Swat, Wojciech, Morita, Takashi, Kuchroo, Vijay, Carroll, Michael C., Kahn, Mark L., Wucherpfennig, Kai W., Turley, Shannon J.
Published in Immunity (Cambridge, Mass.) (24.08.2012)
Published in Immunity (Cambridge, Mass.) (24.08.2012)
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In vivo discovery of immunotherapy targets in the tumour microenvironment
Zhou, Penghui, Shaffer, Donald R., Alvarez Arias, Diana A., Nakazaki, Yukoh, Pos, Wouter, Torres, Alexis J., Cremasco, Viviana, Dougan, Stephanie K., Cowley, Glenn S., Elpek, Kutlu, Brogdon, Jennifer, Lamb, John, Turley, Shannon J., Ploegh, Hidde L., Root, David E., Love, J. Christopher, Dranoff, Glenn, Hacohen, Nir, Cantor, Harvey, Wucherpfennig, Kai W.
Published in Nature (London) (06.02.2014)
Published in Nature (London) (06.02.2014)
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Deciphering the transcriptional network of the dendritic cell lineage
Miller, Jennifer C, Brown, Brian D, Shay, Tal, Gautier, Emmanuel L, Jojic, Vladimir, Cohain, Ariella, Pandey, Gaurav, Leboeuf, Marylene, Elpek, Kutlu G, Helft, Julie, Hashimoto, Daigo, Chow, Andrew, Price, Jeremy, Greter, Melanie, Bogunovic, Milena, Bellemare-Pelletier, Angelique, Frenette, Paul S, Randolph, Gwendalyn J, Turley, Shannon J, Merad, Miriam
Published in Nature immunology (01.09.2012)
Published in Nature immunology (01.09.2012)
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The CLEC-2–podoplanin axis controls the contractility of fibroblastic reticular cells and lymph node microarchitecture
Astarita, Jillian L, Cremasco, Viviana, Fu, Jianxin, Darnell, Max C, Peck, James R, Nieves-Bonilla, Janice M, Song, Kai, Kondo, Yuji, Woodruff, Matthew C, Gogineni, Alvin, Onder, Lucas, Ludewig, Burkhard, Weimer, Robby M, Carroll, Michael C, Mooney, David J, Xia, Lijun, Turley, Shannon J
Published in Nature immunology (01.01.2015)
Published in Nature immunology (01.01.2015)
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B cell homeostasis and follicle confines are governed by fibroblastic reticular cells
Cremasco, Viviana, Woodruff, Matthew C, Onder, Lucas, Cupovic, Jovana, Nieves-Bonilla, Janice M, Schildberg, Frank A, Chang, Jonathan, Cremasco, Floriana, Harvey, Christopher J, Wucherpfennig, Kai, Ludewig, Burkhard, Carroll, Michael C, Turley, Shannon J
Published in Nature immunology (01.10.2014)
Published in Nature immunology (01.10.2014)
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A bird’s eye view of fibroblast heterogeneity: A pan‐disease, pan‐cancer perspective
Pradhan, Rachana N., Krishnamurty, Akshay T., Fletcher, Anne L., Turley, Shannon J., Müller, Sören
Published in Immunological reviews (01.07.2021)
Published in Immunological reviews (01.07.2021)
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Regulated release of nitric oxide by nonhematopoietic stroma controls expansion of the activated T cell pool in lymph nodes
Lukacs-Kornek, Veronika, Malhotra, Deepali, Fletcher, Anne L, Acton, Sophie E, Elpek, Kutlu G, Tayalia, Prakriti, Collier, Ai-ris, Turley, Shannon J
Published in Nature immunology (01.11.2011)
Published in Nature immunology (01.11.2011)
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Transcriptional profiling of stroma from inflamed and resting lymph nodes defines immunological hallmarks
Malhotra, Deepali, Fletcher, Anne L, Astarita, Jillian, Lukacs-Kornek, Veronika, Tayalia, Prakriti, Gonzalez, Santiago F, Elpek, Kutlu G, Chang, Sook Kyung, Knoblich, Konstantin, Hemler, Martin E, Brenner, Michael B, Carroll, Michael C, Mooney, David J, Turley, Shannon J
Published in Nature immunology (01.05.2012)
Published in Nature immunology (01.05.2012)
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A Potent Pan-TGFβ Neutralizing Monoclonal Antibody Elicits Cardiovascular Toxicity in Mice and Cynomolgus Monkeys
Mitra, Mayur S, Lancaster, Karla, Adedeji, Adeyemi O, Palanisamy, Gopinath S, Dave, Rutwij A, Zhong, Fiona, Holdren, Matthew S, Turley, Shannon J, Liang, Wei-Ching, Wu, Yan, Meng, Y Gloria, Vernes, Jean-Michel, Schutten, Melissa M
Published in Toxicological sciences (01.05.2020)
Published in Toxicological sciences (01.05.2020)
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FAP Delineates Heterogeneous and Functionally Divergent Stromal Cells in Immune-Excluded Breast Tumors
Cremasco, Viviana, Astarita, Jillian L, Grauel, Angelo L, Keerthivasan, Shilpa, MacIsaac, Kenzie, Woodruff, Matthew C, Wu, Michael, Spel, Lotte, Santoro, Stephen, Amoozgar, Zohreh, Laszewski, Tyler, Migoni, Sara Cruz, Knoblich, Konstantin, Fletcher, Anne L, LaFleur, Martin, Wucherpfennig, Kai W, Pure, Ellen, Dranoff, Glenn, Carroll, Michael C, Turley, Shannon J
Published in Cancer immunology research (01.12.2018)
Published in Cancer immunology research (01.12.2018)
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The Immunoglobulin Superfamily Receptome Defines Cancer-Relevant Networks Associated with Clinical Outcome
Verschueren, Erik, Husain, Bushra, Yuen, Kobe, Sun, Yi, Paduchuri, Sairupa, Senbabaoglu, Yasin, Lehoux, Isabelle, Arena, Tia A., Wilson, Blair, Lianoglou, Steve, Bakalarski, Corey, Franke, Yvonne, Chan, Pamela, Wong, Athena W., Gonzalez, Lino C., Mariathasan, Sanjeev, Turley, Shannon J., Lill, Jennie R., Martinez-Martin, Nadia
Published in Cell (23.07.2020)
Published in Cell (23.07.2020)
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Homeostatic functions of monocytes and interstitial lung macrophages are regulated via collagen domain-binding receptor LAIR1
Keerthivasan, Shilpa, Şenbabaoğlu, Yasin, Martinez-Martin, Nadia, Husain, Bushra, Verschueren, Erik, Wong, Anne, Yang, Yeqing Angela, Sun, Yonglian, Pham, Victoria, Hinkle, Trent, Oei, Yoko, Madireddi, Shravan, Corpuz, Racquel, Tam, Lucinda, Carlisle, Samantha, Roose-Girma, Merone, Modrusan, Zora, Ye, Zhengmao, Koerber, James T., Turley, Shannon J.
Published in Immunity (Cambridge, Mass.) (13.07.2021)
Published in Immunity (Cambridge, Mass.) (13.07.2021)
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The neutrophil protein CD177 is a novel PDPN receptor that regulates human cancer-associated fibroblast physiology
Astarita, Jillian L, Keerthivasan, Shilpa, Husain, Bushra, Şenbabaoğlu, Yasin, Verschueren, Erik, Gierke, Sarah, Pham, Victoria C, Peterson, Sean M, Chalouni, Cecile, Pierce, Andrew A, Lill, Jennie R, Gonzalez, Lino C, Martinez-Martin, Nadia, Turley, Shannon J
Published in PloS one (08.12.2021)
Published in PloS one (08.12.2021)
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Tumor elastography and its association with collagen and the tumor microenvironment
Riegler, Johannes, Labyed, Yassin, Rosenzweig, Stephen, Javinal, Vincent, Castiglioni, Alessandra, Dominguez, Claudia X, Long, Jason E, Li, Qingling, Sandoval, Wendy, Junttila, Melissa R, Turley, Shannon J, Schartner, Jill M, Carano, Richard
Published in Clinical cancer research (15.09.2018)
Published in Clinical cancer research (15.09.2018)
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TGF-β regulates the stem-like state of PD-1+ TCF-1+ virus-specific CD8 T cells during chronic infection
Hu, Yinghong, Hudson, William H, Kissick, Haydn T, Medina, Christopher B, Baptista, Antonio P, Ma, Chaoyu, Liao, Wei, Germain, Ronald N, Turley, Shannon J, Zhang, Nu, Ahmed, Rafi
Published in The Journal of experimental medicine (03.10.2022)
Published in The Journal of experimental medicine (03.10.2022)
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Integrated digital pathology and transcriptome analysis identifies molecular mediators of T-cell exclusion in ovarian cancer
Desbois, Mélanie, Udyavar, Akshata R., Ryner, Lisa, Kozlowski, Cleopatra, Guan, Yinghui, Dürrbaum, Milena, Lu, Shan, Fortin, Jean-Philippe, Koeppen, Hartmut, Ziai, James, Chang, Ching-Wei, Keerthivasan, Shilpa, Plante, Marie, Bourgon, Richard, Bais, Carlos, Hegde, Priti, Daemen, Anneleen, Turley, Shannon, Wang, Yulei
Published in Nature communications (04.11.2020)
Published in Nature communications (04.11.2020)
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The stromal and haematopoietic antigen-presenting cells that reside in secondary lymphoid organs
Turley, Shannon J, Fletcher, Anne L, Elpek, Kutlu G
Published in Nature reviews. Immunology (01.12.2010)
Published in Nature reviews. Immunology (01.12.2010)
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