Increasing skeletal muscle carnitine content in older individuals increases whole‐body fat oxidation during moderate‐intensity exercise
Chee, Carolyn, Shannon, Chris E., Burns, Aisling, Selby, Anna L., Wilkinson, Daniel, Smith, Kenneth, Greenhaff, Paul L., Stephens, Francis B.
Published in Aging cell (01.02.2021)
Published in Aging cell (01.02.2021)
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Journal Article
Insulin resistance is mechanistically linked to hepatic mitochondrial remodeling in non-alcoholic fatty liver disease
Shannon, Chris E., Ragavan, Mukundan, Palavicini, Juan Pablo, Fourcaudot, Marcel, Bakewell, Terry M, Valdez, Ivan A., Ayala, Iriscilla, Jin, Eunsook S., Madesh, Muniswamy, Han, Xianlin, Merritt, Matthew E., Norton, Luke
Published in Molecular metabolism (Germany) (01.03.2021)
Published in Molecular metabolism (Germany) (01.03.2021)
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Journal Article
Skeletal muscle carnitine loading increases energy expenditure, modulates fuel metabolism gene networks and prevents body fat accumulation in humans
Stephens, Francis B., Wall, Benjamin T., Marimuthu, Kanagaraj, Shannon, Chris E., Constantin‐Teodosiu, Dumitru, Macdonald, Ian A., Greenhaff, Paul L.
Published in The Journal of physiology (15.09.2013)
Published in The Journal of physiology (15.09.2013)
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Journal Article
The tumor suppressor TMEM127 regulates insulin sensitivity in a tissue-specific manner
Srikantan, Subramanya, Deng, Yilun, Cheng, Zi-Ming, Luo, Anqi, Qin, Yuejuan, Gao, Qing, Sande-Docor, Glaiza-Mae, Tao, Sifan, Zhang, Xingyu, Harper, Nathan, Shannon, Chris E, Fourcaudot, Marcel, Li, Zhi, Kasinath, Balakuntalam S, Harrison, Stephen, Ahuja, Sunil, Reddick, Robert L, Dong, Lily Q, Abdul-Ghani, Muhammad, Norton, Luke, Aguiar, Ricardo C T, Dahia, Patricia L M
Published in Nature communications (17.10.2019)
Published in Nature communications (17.10.2019)
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Journal Article
Fish oil omega-3 fatty acids partially prevent lipid-induced insulin resistance in human skeletal muscle without limiting acylcarnitine accumulation
Stephens, Francis B, Mendis, Buddhike, Shannon, Chris E, Cooper, Scott, Ortori, Catharine A, Barrett, David A, Mansell, Peter, Tsintzas, Kostas
Published in Clinical science (1979) (01.09.2014)
Published in Clinical science (1979) (01.09.2014)
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Journal Article
24 The Transcriptional Function of TCF7L2 is Spatially Restricted in Liver and Regulates Zonated Metabolic Pathways Which Contribute to Liver Disease
Ayala, Iriscilla Imabary, Hebbale, Skanda K, Shannon, Chris E., Valdez, Ivan, Fourcaudot, Marcel, Bakewell, Terry M., Sholto, Madelaine, Vallim, Thomas, Heikkinen, Sami
Published in Journal of clinical and translational science (01.04.2024)
Published in Journal of clinical and translational science (01.04.2024)
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Journal Article
345 The Role of TCF7L2 in Hepatic Metabolic Zonation
Ayala, Iriscilla I., Hebbale, Skanda K, Shannon, Chris E., Valdez, Ivan, Fourcaudot, Marcel, Bakewell, Terry M., Sholto, Madelaine, Vallim, Thomas, Heikkinen, Sami
Published in Journal of clinical and translational science (01.04.2023)
Published in Journal of clinical and translational science (01.04.2023)
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Journal Article
Regulation of ANGPTL8 in liver and adipose tissue by nutritional and hormonal signals and its effect on glucose homeostasis in mice
Zhang, Lu, Shannon, Chris E, Bakewell, Terry M, Abdul-Ghani, Muhammad A, Fourcaudot, Marcel, Norton, Luke
Published in American journal of physiology: endocrinology and metabolism (01.05.2020)
Published in American journal of physiology: endocrinology and metabolism (01.05.2020)
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Journal Article
Relative Contribution of Intramyocellular Lipid to Whole-Body Fat Oxidation Is Reduced With Age but Subsarcolemmal Lipid Accumulation and Insulin Resistance Are Only Associated With Overweight Individuals
Chee, Carolyn, Shannon, Chris E, Burns, Aisling, Selby, Anna L, Wilkinson, Daniel, Smith, Kenneth, Greenhaff, Paul L, Stephens, Francis B
Published in Diabetes (New York, N.Y.) (01.04.2016)
Published in Diabetes (New York, N.Y.) (01.04.2016)
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Journal Article
Lipid-induced insulin resistance is associated with an impaired skeletal muscle protein synthetic response to amino acid ingestion in healthy young men
Stephens, Francis B, Chee, Carolyn, Wall, Benjamin T, Murton, Andrew J, Shannon, Chris E, van Loon, Luc J C, Tsintzas, Kostas
Published in Diabetes (New York, N.Y.) (01.05.2015)
Published in Diabetes (New York, N.Y.) (01.05.2015)
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Journal Article
Persistent Inflammatory Lipotoxicity Impedes Pancreatic β-cell Function in Diet-Induced Obese Mice Despite Correction of Glucotoxicity
Valdez, Ivan A, Juan Pablo Palavicini, Bakewell, Terry M, Fourcaudot, Marcel, Ayala, Iriscilla, Xu, Ziying, Khattab, Ahmed, Han, Xianlin, Shannon, Chris E, Norton, Luke
Published in bioRxiv (31.05.2022)
Published in bioRxiv (31.05.2022)
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Paper
Hepatic Mitochondrial Remodeling is Mechanistically Linked to Insulin Resistance in Nonalcoholic Fatty Liver Disease
Shannon, Chris E, Ragavan, Mukundan, Juan Pablo Palavicini, Fourcaudot, Marcel, Bakewell, Terry, Jin, Eunsook S, Malloy, Craig R, Han, Xianlin, Merritt, Matthew E, Norton, Luke
Published in bioRxiv (16.02.2020)
Published in bioRxiv (16.02.2020)
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Paper