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Preclinical profile of a dopamine D1 potentiator suggests therapeutic utility in neurological and psychiatric disorders
Bruns, Robert F., Mitchell, Stephen N., Wafford, Keith A., Harper, Alex J., Shanks, Elaine A., Carter, Guy, O'Neill, Michael J., Murray, Tracey K., Eastwood, Brian J., Schaus, John M., Beck, James P., Hao, Junliang, Witkin, Jeffrey M., Li, Xia, Chernet, Eyassu, Katner, Jason S., Wang, Hong, Ryder, John W., Masquelin, Meghane E., Thompson, Linda K., Love, Patrick L., Maren, Deanna L., Falcone, Julie F., Menezes, Michelle M., Zhang, Linli, Yang, Charles R., Svensson, Kjell A.
Published in Neuropharmacology (01.01.2018)
Published in Neuropharmacology (01.01.2018)
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REM sleep homeostasis in the absence of REM sleep: Effects of antidepressants
McCarthy, Andrew, Wafford, Keith, Shanks, Elaine, Ligocki, Marcin, Edgar, Dale M., Dijk, Derk-Jan
Published in Neuropharmacology (01.09.2016)
Published in Neuropharmacology (01.09.2016)
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Attenuation of the effects of fluoxetine on serotonergic neuronal activity by pindolol in rats
Rasmussen, Kurt, McCreary, Andrew C., Shanks, Elaine A.
Published in Neuroscience letters (23.01.2004)
Published in Neuroscience letters (23.01.2004)
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Identification of a Safe and Tolerable Carbamazepine Dosing Paradigm that Facilitates Effective Evaluation of CYP3A4 Induction
Datta‐Mannan, Amita, Shanks, Elaine, Yuen, Eunice, Jin, Yan, Rehmel, Jessica, Hall, Stephen David
Published in Clinical pharmacology and therapeutics (01.10.2024)
Published in Clinical pharmacology and therapeutics (01.10.2024)
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The dopamine D1 receptor positive allosteric modulator mevidalen (LY3154207) enhances wakefulness in the humanized D1 mouse and in sleep deprived healthy volunteers
McCarthy, Andrew P., Svensson, Kjell A., Shanks, Elaine, Brittain, Claire, Eastwood, Brian J., Kielbasa, William, Biglan, Kevin M., Wafford, Keith A.
Published in The Journal of pharmacology and experimental therapeutics (01.03.2022)
Published in The Journal of pharmacology and experimental therapeutics (01.03.2022)
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Abstract P4-10-07: Evaluation of pharmacokinetics and safety of imlunestrant in participants with hepatic impairment
White, Stephanie, Shanks, Elaine, Yuen, Eunice, Hall, Stephen David, Cruz, Vivian Rodriguez, Wang, Xuejing
Published in Clinical cancer research (13.06.2025)
Published in Clinical cancer research (13.06.2025)
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The Dopamine D1 Receptor Positive Allosteric Modulator Mevidalen (LY3154207) Enhances Wakefulness in the Humanized D1 Mouse and in Sleep-Deprived Healthy Male Volunteers
McCarthy, Andrew P., Svensson, Kjell A., Shanks, Elaine, Brittain, Claire, Eastwood, Brian J., Kielbasa, William, Biglan, Kevin M., Wafford, Keith A.
Published in The Journal of pharmacology and experimental therapeutics (01.03.2022)
Published in The Journal of pharmacology and experimental therapeutics (01.03.2022)
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Disposition and Absolute Bioavailability of Oral Imlunestrant in Healthy Women: A Phase 1, Open-Label Study
Datta-Mannan, Amita, Czeskis, Boris, Shanks, Elaine, Yuen, Eunice, Hall, Stephen, Rodriguez Cruz, Vivian, Cassidy, Kenneth
Published in Clinical pharmacology in drug development (24.06.2025)
Published in Clinical pharmacology in drug development (24.06.2025)
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Investigating the role of mGluR2 versus mGluR3 in antipsychotic-like effects, sleep-wake architecture and network oscillatory activity using novel Han Wistar rats lacking mGluR2 expression
Wood, Christian M., Wafford, Keith A., McCarthy, Andrew P., Hewes, Nicola, Shanks, Elaine, Lodge, David, Robinson, Emma S.J.
Published in Neuropharmacology (15.09.2018)
Published in Neuropharmacology (15.09.2018)
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In vitro characterisation of the novel positive allosteric modulators of the mGlu5 receptor, LSN2463359 and LSN2814617, and their effects on sleep architecture and operant responding in the rat
Gilmour, Gary, Broad, Lisa M., Wafford, Keith A., Britton, Thomas, Colvin, Ellen M., Fivush, Adam, Gastambide, Francois, Getman, Brian, Heinz, Beverly A., McCarthy, Andrew P., Prieto, Lourdes, Shanks, Elaine, Smith, Janice W., Taboada, Lorena, Edgar, Dale M., Tricklebank, Mark D.
Published in Neuropharmacology (01.01.2013)
Published in Neuropharmacology (01.01.2013)
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P1‐273: Changes in sleep/wake parameters in male PD‐APP transgenic mice
Shanks, Elaine, Wafford, Keith, Hewes, Nicola, McCarthy, Andrew, Kinsley, Peter, Edgar, Dale
Published in Alzheimer's & dementia (01.07.2012)
Published in Alzheimer's & dementia (01.07.2012)
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Changes in sleep/wake parameters in male PD-APP transgenic mice
Shanks, Elaine, Wafford, Keith, Hewes, Nicola, McCarthy, Andrew, Kinsley, Peter, Edgar, Dale
Published in Alzheimer's & dementia (01.07.2012)
Published in Alzheimer's & dementia (01.07.2012)
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Longitudinal changes in EEG power, sleep cycles and behaviour in a tau model of neurodegeneration
Holton, Christopher, Hanley, Nicola, Shanks, Elaine, Oxley, Penny, McCarthy, Andrew, Eastwood, Brian J, Murray, Tracey K, Nickerson, Aidan, Wafford, Keith A
Published in Alzheimer's Research and Therapy (04.06.2020)
Published in Alzheimer's Research and Therapy (04.06.2020)
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