The human heart contains distinct macrophage subsets with divergent origins and functions
Bajpai, Geetika, Schneider, Caralin, Wong, Nicole, Bredemeyer, Andrea, Hulsmans, Maarten, Nahrendorf, Matthias, Epelman, Slava, Kreisel, Daniel, Liu, Yongjian, Itoh, Akinobu, Shankar, Thirupura S, Selzman, Craig H, Drakos, Stavros G, Lavine, Kory J
Published in Nature medicine (01.08.2018)
Published in Nature medicine (01.08.2018)
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The pyruvate-lactate axis modulates cardiac hypertrophy and heart failure
Cluntun, Ahmad A., Badolia, Rachit, Lettlova, Sandra, Parnell, K. Mark, Shankar, Thirupura S., Diakos, Nikolaos A., Olson, Kristofor A., Taleb, Iosif, Tatum, Sean M., Berg, Jordan A., Cunningham, Corey N., Van Ry, Tyler, Bott, Alex J., Krokidi, Aspasia Thodou, Fogarty, Sarah, Skedros, Sophia, Swiatek, Wojciech I., Yu, Xuejing, Luo, Bai, Merx, Shannon, Navankasattusas, Sutip, Cox, James E., Ducker, Gregory S., Holland, William L., McKellar, Stephen H., Rutter, Jared, Drakos, Stavros G.
Published in Cell metabolism (02.03.2021)
Published in Cell metabolism (02.03.2021)
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Perm1 regulates cardiac energetics as a downstream target of the histone methyltransferase Smyd1
Oka, Shin-Ichi, Sabry, Amira D, Horiuchi, Amanda K, Cawley, Keiko M, O'Very, Sean A, Zaitsev, Maria A, Shankar, Thirupura S, Byun, Jaemin, Mukai, Risa, Xu, Xiaoyong, Torres, Natalia S, Kumar, Anil, Yazawa, Masayuki, Ling, Jing, Taleb, Iosif, Saijoh, Yukio, Drakos, Stavros G, Sadoshima, Junichi, Warren, Junco S
Published in PloS one (23.06.2020)
Published in PloS one (23.06.2020)
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The Role of Nonglycolytic Glucose Metabolism in Myocardial Recovery Upon Mechanical Unloading and Circulatory Support in Chronic Heart Failure
Badolia, Rachit, Ramadurai, Dinesh K.A, Abel, E Dale, Ferrin, Peter, Taleb, Iosif, Shankar, Thirupura S, Krokidi, Aspasia Thodou, Navankasattusas, Sutip, McKellar, Stephen H, Yin, Michael, Kfoury, Abdallah G, Wever-Pinzon, Omar, Fang, James C, Selzman, Craig H, Chaudhuri, Dipayan, Rutter, Jared, Drakos, Stavros G
Published in Circulation (New York, N.Y.) (21.07.2020)
Published in Circulation (New York, N.Y.) (21.07.2020)
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Journal Article
Cardiac-specific deletion of voltage dependent anion channel 2 leads to dilated cardiomyopathy by altering calcium homeostasis
Shankar, Thirupura S, Ramadurai, Dinesh K A, Steinhorst, Kira, Sommakia, Salah, Badolia, Rachit, Thodou Krokidi, Aspasia, Calder, Dallen, Navankasattusas, Sutip, Sander, Paulina, Kwon, Oh Sung, Aravamudhan, Aishwarya, Ling, Jing, Dendorfer, Andreas, Xie, Changmin, Kwon, Ohyun, Cheng, Emily H Y, Whitehead, Kevin J, Gudermann, Thomas, Richardson, Russel S, Sachse, Frank B, Schredelseker, Johann, Spitzer, Kenneth W, Chaudhuri, Dipayan, Drakos, Stavros G
Published in Nature communications (28.07.2021)
Published in Nature communications (28.07.2021)
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Ryanodine Receptor Staining Identifies Viable Cardiomyocytes in Human and Rabbit Cardiac Tissue Slices
Pfeuffer, Ann-Katrin M, Küpfer, Linda K, Shankar, Thirupura S, Drakos, Stavros G, Volk, Tilmann, Seidel, Thomas
Published in International journal of molecular sciences (01.09.2023)
Published in International journal of molecular sciences (01.09.2023)
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Journal Article
Distinct Transcriptomic and Proteomic Profile Specifies Patients Who Have Heart Failure With Potential of Myocardial Recovery on Mechanical Unloading and Circulatory Support
Drakos, Stavros G, Badolia, Rachit, Makaju, Aman, Kyriakopoulos, Christos P, Wever-Pinzon, Omar, Tracy, Christopher M, Bakhtina, Anna, Bia, Ryan, Parnell, Timothy, Taleb, Iosif, Ramadurai, Dinesh K A, Navankasattusas, Sutip, Dranow, Elizabeth, Hanff, Thomas C, Tseliou, Eleni, Shankar, Thirupura S, Visker, Joseph, Hamouche, Rana, Stauder, Elizabeth L, Caine, William T, Alharethi, Rami, Selzman, Craig H, Franklin, Sarah
Published in Circulation (New York, N.Y.) (31.01.2023)
Published in Circulation (New York, N.Y.) (31.01.2023)
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Etiology-Specific Remodeling in Ventricular Tissue of Heart Failure Patients and Its Implications for Computational Modeling of Electrical Conduction
Sankarankutty, Aparna C, Greiner, Joachim, Bragard, Jean, Visker, Joseph R, Shankar, Thirupura S, Kyriakopoulos, Christos P, Drakos, Stavros G, Sachse, Frank B
Published in Frontiers in physiology (05.10.2021)
Published in Frontiers in physiology (05.10.2021)
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PERM1 regulates energy metabolism in the heart via ERRα/PGC-1α axis
Oka, Shin-Ichi, Sreedevi, Karthi, Shankar, Thirupura S, Yedla, Shreya, Arowa, Sumaita, James, Amina, Stone, Kathryn G, Olmos, Katia, Sabry, Amira D, Horiuchi, Amanda, Cawley, Keiko M, O'very, Sean A, Tong, Mingming, Byun, Jaemin, Xu, Xiaoyong, Kashyap, Sanchita, Mourad, Youssef, Vehra, Omair, Calder, Dallen, Lunde, Ty, Liu, Tong, Li, Hong, Mashchek, J Alan, Cox, James, Saijoh, Yukio, Drakos, Stavros G, Warren, Junco S
Published in Frontiers in cardiovascular medicine (07.11.2022)
Published in Frontiers in cardiovascular medicine (07.11.2022)
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Journal Article
The Role of Non-Glycolytic Glucose Metabolism in Myocardial Recovery upon Mechanical Unloading and Circulatory Support in Chronic Heart Failure
Badolia, Rachit, Ramadurai, Dinesh K A, Abel, E Dale, Ferrin, Peter, Taleb, Iosif, Shankar, Thirupura S, Thodou Krokidi, Aspasia, Navankasattusas, Sutip, McKellar, Stephen H, Yin, Michael, Kfoury, Abdallah G, Wever-Pinzon, Omar, Fang, James C, Selzman, Craig H, Chaudhuri, Dipayan, Rutter, Jared, Drakos, Stavros G
Published in Circulation (New York, N.Y.) (30.04.2020)
Published in Circulation (New York, N.Y.) (30.04.2020)
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Enhancing mitochondrial pyruvate metabolism ameliorates ischemic reperfusion injury in the heart
Visker, Joseph R., Cluntun, Ahmad A., Velasco-Silva, Jesse N., Eberhardt, David R., Cedeño-Rosario, Luis, Shankar, Thirupura S., Hamouche, Rana, Ling, Jing, Kwak, Hyoin, Hillas, J. Yanni, Aist, Ian, Tseliou, Eleni, Navankasattusas, Sutip, Chaudhuri, Dipayan, Ducker, Gregory S., Drakos, Stavros G., Rutter, Jared
Published in JCI insight (25.07.2024)
Published in JCI insight (25.07.2024)
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Defining cardiac functional recovery in end-stage heart failure at single-cell resolution
Amrute, Junedh M, Lai, Lulu, Ma, Pan, Koenig, Andrew L, Kamimoto, Kenji, Bredemeyer, Andrea, Shankar, Thirupura S, Kuppe, Christoph, Kadyrov, Farid F, Schulte, Linda J, Stoutenburg, Dylan, Kopecky, Benjamin J, Navankasattusas, Sutip, Visker, Joseph, Morris, Samantha A, Kramann, Rafael, Leuschner, Florian, Mann, Douglas L, Drakos, Stavros G, Lavine, Kory J
Published in Nature cardiovascular research (01.04.2023)
Published in Nature cardiovascular research (01.04.2023)
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Journal Article
Clinical-transcriptional prioritization of the circulating proteome in human heart failure
Perry, Andrew S., Amancherla, Kaushik, Huang, Xiaoning, Lance, Michelle L., Farber-Eger, Eric, Gajjar, Priya, Amrute, Junedh, Stolze, Lindsey, Zhao, Shilin, Sheng, Quanhu, Joynes, Cassandra M., Peng, Zhongsheng, Tanaka, Toshiko, Drakos, Stavros G., Lavine, Kory J., Selzman, Craig, Visker, Joseph R., Shankar, Thirupura S., Ferrucci, Luigi, Das, Saumya, Wilcox, Jane, Patel, Ravi B., Kalhan, Ravi, Shah, Sanjiv J., Walker, Keenan A., Wells, Quinn, Tucker, Nathan, Nayor, Matthew, Shah, Ravi V., Khan, Sadiya S.
Published in Cell reports. Medicine (01.09.2024)
Published in Cell reports. Medicine (01.09.2024)
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Journal Article
Enhancing mitochondrial pyruvate metabolism ameliorates myocardial ischemic reperfusion injury
Visker, Joseph R, Cluntun, Ahmad A, Velasco-Silva, Jesse N, Eberhardt, David R, Shankar, Thirupura S, Hamouche, Rana, Ling, Jing, Kwak, Hyoin, Hillas, Yanni, Aist, Ian, Tseliou, Eleni, Navankasattusas, Sutip, Chaudhuri, Dipayan, Ducker, Gregory S, Drakos, Stavros G, Rutter, Jared
Published in bioRxiv (04.02.2024)
Published in bioRxiv (04.02.2024)
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Remodeling of t-system and proteins underlying excitation-contraction coupling in aging versus failing human heart
Lyu, Yankun, Verma, Vipin K., Lee, Younjee, Taleb, Iosif, Badolia, Rachit, Shankar, Thirupura S., Kyriakopoulos, Christos P., Selzman, Craig H., Caine, William, Alharethi, Rami, Navankasattusas, Sutip, Seidel, Thomas, Drakos, Stavros G., Sachse, Frank B.
Published in npj aging and mechanisms of disease (28.05.2021)
Published in npj aging and mechanisms of disease (28.05.2021)
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Journal Article
Integrating molecular and clinical variables to predict myocardial recovery
Visker, Joseph R, Brintz, Ben J, Kyriakopoulos, Christos P, Hillas, Yanni, Taleb, Iosif, Badolia, Rachit, Shankar, Thirupura S, Amrute, Junedh M, Ling, Jing, Hamouche, Rana, Tseliou, Eleni, Navankasattusas, Sutip, Wever-Pinzon, Omar, Ducker, Gregory S, Holland, William L, Summers, Scott A, Koenig, Steven C, Hanff, Thomas C, Lavine, Kory J, Murali, Srinivas, Bailey, Stephen, Alharethi, Rami, Selzman, Craig H, Shah, Palak, Slaughter, Mark S, Kanwar, Manreet K, Drakos, Stavros G
Published in bioRxiv : the preprint server for biology (20.04.2024)
Published in bioRxiv : the preprint server for biology (20.04.2024)
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Abstract 14841: Perm1 is a Novel Regulator of O-GlcNAcylation in the Heart
SREEDEVI, KARTHI, Shankar, Thirupura S, Yedla, Shreya, James, Amina, arowa, sumaita, Zaitsev, Alexey V, Saijoh, Yukio, Drakos, Stavros G, Warren, Junco S
Published in Circulation (New York, N.Y.) (08.11.2022)
Published in Circulation (New York, N.Y.) (08.11.2022)
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Abstract 9124: The Role of Mitochondrial Pyruvate Carrier on Myocardial Salvage Following Acute Myocardial Infarction
Visker, Joseph R, LING, JING, Kwak, Hyoin, Shankar, Thirupura S S, Velasco, Jesse, Thodou, Apasia S, Navankasattusas, Sutip, Ducker, Gregory, Rutter, Jared P, Drakos, Stavros G
Published in Circulation (New York, N.Y.) (16.11.2021)
Published in Circulation (New York, N.Y.) (16.11.2021)
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