Dual blockade of the lipid kinase PIP4Ks and mitotic pathways leads to cancer-selective lethality
Kitagawa, Mayumi, Liao, Pei-Ju, Lee, Kyung Hee, Wong, Jasmine, Shang, See Cheng, Minami, Noriaki, Sampetrean, Oltea, Saya, Hideyuki, Lingyun, Dai, Prabhu, Nayana, Diam, Go Ka, Sobota, Radoslaw, Larsson, Andreas, Nordlund, Pär, McCormick, Frank, Ghosh, Sujoy, Epstein, David M, Dymock, Brian W, Lee, Sang Hyun
Published in Nature communications (19.12.2017)
Published in Nature communications (19.12.2017)
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Journal Article
Prodrugs of the cancer cell selective anti-cancer agent (Z)-2-(1H-indo1-3-yl)-3-(isoquinolin-5-yeacrylonitrile (A131) are orally efficacious in a mouse model of resistant colon cancer
See, Cheng Shang, Kitagawa, Mayumi, Liao, Pei-Ju, Lee, Kyung Hee, Wong, Jasmine, Lee, Sang Hyun, Dymock, Brian W.
Published in Bioorganic & medicinal chemistry letters (15.01.2019)
Published in Bioorganic & medicinal chemistry letters (15.01.2019)
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Journal Article
Discovery of the cancer cell selective dual acting anti-cancer agent (Z)-2-(1H-indol-3-yl)-3-(isoquinolin-5-yl)acrylonitrile (A131)
See, Cheng Shang, Kitagawa, Mayumi, Liao, Pei-Ju, Lee, Kyung Hee, Wong, Jasmine, Lee, Sang Hyun, Dymock, Brian W.
Published in European journal of medicinal chemistry (05.08.2018)
Published in European journal of medicinal chemistry (05.08.2018)
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Journal Article
Prodrugs of the cancer cell selective anti-cancer agent (Z)-2-(1H-indol-3-yl)-3-(isoquinolin-5-yl)acrylonitrile (A131) are orally efficacious in a mouse model of resistant colon cancer
See, Cheng Shang, Kitagawa, Mayumi, Liao, Pei-Ju, Lee, Kyung Hee, Wong, Jasmine, Lee, Sang Hyun, Dymock, Brian W.
Published in Bioorganic & medicinal chemistry letters (15.01.2019)
Published in Bioorganic & medicinal chemistry letters (15.01.2019)
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Journal Article
Utilizing mobile networks for the detection of clinically relevant interactions between chemotherapy regimens and complementary and alternative medicines
Yap, Kevin Yi-Lwern, See, Cheng Shang, Kuo, En Yi, Chui, Wai Keung, Chan, Alexandre
Published in The journal of alternative and complementary medicine (New York, N.Y.) (01.02.2012)
Published in The journal of alternative and complementary medicine (New York, N.Y.) (01.02.2012)
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Journal Article
(Z)-2-(1H-INDOL-3-YL)-3-(ISOQUINOLIN-5-YL)ACRYLONITRILE DERIVATIVES AND RELATED COMPOUNDS WITH LYSOSOME INHIBITORY AND ANTI-MITOTIC ACTIVITY FOR TREATING HYPERPROLIFERATIVE DISEASES
DYMOCK, Brian William, LEE, Sang Hyun, SEE, Cheng Shang, KITAGAWA, Mayumi
Year of Publication 10.06.2020
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Year of Publication 10.06.2020
Patent
SELECTIVE ANTI-CANCER COMPOUNDS
DYMOCK, Brian William, LEE, Sang Hyun, SEE, Cheng Shang, KITAGAWA, Mayumi
Year of Publication 13.03.2019
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Year of Publication 13.03.2019
Patent
SELECTIVE ANTI-CANCER COMPOUNDS
DYMOCK, Brian William, LEE, Sang Hyun, SEE, Cheng Shang, KITAGAWA, Mayumi
Year of Publication 28.06.2018
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Year of Publication 28.06.2018
Patent
(Z)-2-(1H-INDOL-3-YL)-3-(ISOQUINOLIN-5-YL)ACRYLONITRILE DERIVATIVES AND RELATED COMPOUNDS WITH LYSOSOME INHIBITORY AND ANTI-MITOTIC ACTIVITY FOR TREATING HYPERPROLIFERATIVE DISEASES
DYMOCK, Brian William, LEE, Sang Hyun, SEE, Cheng Shang, KITAGAWA, Mayumi
Year of Publication 18.04.2018
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Year of Publication 18.04.2018
Patent
SELECTIVE ANTI-CANCER COMPOUNDS
DYMOCK, Brian William, LEE, Sang Hyun, SEE, Cheng Shang, KITAGAWA, Mayumi
Year of Publication 15.12.2016
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Year of Publication 15.12.2016
Patent
Derivados de z)-2-(1h-indol-3-il)-3-(isoquinolin-5-il)acrilonitrilo y compuestos relacionados con actividad inhibitoria de lisosoma y antimitótica para el tratamiento de enfermedades hiperproliferativas
DYMOCK, Brian William, LEE, Sang Hyun, SEE, Cheng Shang, KITAGAWA, Mayumi
Year of Publication 09.03.2021
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Year of Publication 09.03.2021
Patent
SELECTIVE ANTI-CANCER COMPOUNDS
KITAGAWA MAYUMI, DYMOCK BRIAN WILLIAM, SEE CHENG SHANG, LEE SANG HYUN
Year of Publication 17.04.2018
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Year of Publication 17.04.2018
Patent