19 Preclinical CD3-based mouse models for evaluation of bi-specific T-cell engager antibodies
Shang, Chengzhang, Li, Chong, Liu, Chang, Zhang, Jay, Shen, Yuelei
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
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1163 A novel bispecific antibody-drug conjugate targeting PTK7 and TROP2, BCG033, demonstrates preclinical efficacy against triple-negative breast cancer xenografts
Yao, Sufei, Shang, Chengzhang, An, Gao, Frank An, W, Guo, Chaoshe, Yang, Yi
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
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1153 BCG022: a HER3×MET bispecific antibody-drug conjugate (BsADC) targeting key mechanisms of bypass resistance in multiple tumor types
Li, Zhuolin, Shang, Chengzhang, Han, Zhenyan, An, Gao, Frank An, W, Guo, Chaoshe, Yang, Yi
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
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1152 DM001: A novel bispecific ADC targeting TROP2 and EGFR with potent anti-tumor efficacy in PDX models
Li, Zhuolin, Shang, Chengzhang, Guan, Xuewa, An, Gao, Guo, Yuming, Frank An, W, Guo, Chaoshe, Yang, Yi
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
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1165 Preclinical evaluation of fully human bispecific antibody-drug candidates targeting HER3 and the juxtamembrane region of MUC1
Zhang, Yifu, Shang, Chengzhang, Wang, Nannan, Frank An, W, Guo, Chaoshe, An, Gao, Yang, Yi
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
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1164 BSA01, a bispecific antibody-drug conjugate targeting EGFR and membrane-bound MUC-1-C, exhibits anti-tumor efficacy in vivo
Zhang, Yifu, Shang, Chengzhang, Wang, Anqi, Zhang, Jia, Liu, Yuji, Li, Hao, Li, Xiaopeng, An, Gao, Frank An, W, Guo, Chaoshe, Yang, Yi
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
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1150 DM005, an EGFR × MET bispecific antibody-drug conjugate, showed robust anti-tumor activity in PDX models
Han, Yanfei, Dai, Wenjuan, Shang, Chengzhang, Li, Zhuolin, Han, Zhenyan, Li, Jun, Cui, Zixu, An, Gao, Hao, Wanjun, Liu, Yujie, Li, Hao, Liu, Baihong, Frank An, W, Guo, Chaoshe, Yang, Yi, Shen, Yuelei
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
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Abstract 497: Human CD73 knock-in mice facilitate evaluation of in vivo efficacy of anti-human CD73 cancer immunotherapies
Shang, Chengzhang, Li, Huilin, Zhang, Jing, Lin, Eugene, Yu, Luke (Zhaoxue), Shen, Yuelei
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Abstract 5196: Novel humanized CD36 mouse model for therapeutic studies
Wang, Linlin, Liu, Chang, Soto, Rebecca, Shang, Chengzhang, Lin, Qingcong
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Abstract 432: Development of a novel engineered B2M mouse strain on B-NDG background that specifically eliminates MHC I expression while retaining normal FcRn-mediated antibody retention
An, W. Frank, Gao, Lan, Wang, Xiaoen, Sharma, Shruti, Li, Kaiqi, Gao, Xiqiang, Shang, Chengzhang, Hu, Yuting
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Abstract 2945: Novel engineered B-NDG B2M/KO mice plus and steroid treated B-NDG Mice shows delayed GvHD response when engrafted with hPBMC
Gao, Lan, Sharma, Shruti, Lin, Eugene, Wang, Xiaoen, Shang, Chengzhang, Hu, Yuting, An, W. Frank, Chawla, Mehma Kaur, Li, Kaiqi, Lin, Qingcong, Yu, Zhaoxue (Luke), Liu, Yujie
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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