Plasticity of an Ultrafast Interaction between Nucleoporins and Nuclear Transport Receptors
Milles, Sigrid, Mercadante, Davide, Aramburu, Iker Valle, Jensen, Malene Ringkjøbing, Banterle, Niccolò, Koehler, Christine, Tyagi, Swati, Clarke, Jane, Shammas, Sarah L., Blackledge, Martin, Gräter, Frauke, Lemke, Edward A.
Published in Cell (22.10.2015)
Published in Cell (22.10.2015)
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Journal Article
A mechanistic model of tau amyloid aggregation based on direct observation of oligomers
Shammas, Sarah L., Garcia, Gonzalo A., Kumar, Satish, Kjaergaard, Magnus, Horrocks, Mathew H., Shivji, Nadia, Mandelkow, Eva, Knowles, Tuomas P.J., Mandelkow, Eckhard, Klenerman, David
Published in Nature communications (30.04.2015)
Published in Nature communications (30.04.2015)
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Journal Article
Interplay between partner and ligand facilitates the folding and binding of an intrinsically disordered protein
Rogers, Joseph M., Oleinikovas, Vladimiras, Shammas, Sarah L., Wong, Chi T., De Sancho, David, Baker, Christopher M., Clarke, Jane
Published in Proceedings of the National Academy of Sciences - PNAS (28.10.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (28.10.2014)
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Journal Article
Perturbation of the Stability of Amyloid Fibrils through Alteration of Electrostatic Interactions
Shammas, Sarah L., Knowles, Tuomas P.J., Baldwin, Andrew J., MacPhee, Cait E., Welland, Mark E., Dobson, Christopher M., Devlin, Glyn L.
Published in Biophysical journal (08.06.2011)
Published in Biophysical journal (08.06.2011)
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Journal Article
Binding of the Molecular Chaperone αB-Crystallin to Aβ Amyloid Fibrils Inhibits Fibril Elongation
Shammas, Sarah L., Waudby, Christopher A., Wang, Shuyu, Buell, Alexander K., Knowles, Tuomas P.J., Ecroyd, Heath, Welland, Mark E., Carver, John A., Dobson, Christopher M., Meehan, Sarah
Published in Biophysical journal (05.10.2011)
Published in Biophysical journal (05.10.2011)
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Journal Article
Conserved Helix-Flanking Prolines Modulate Intrinsically Disordered Protein:Target Affinity by Altering the Lifetime of the Bound Complex
Crabtree, Michael D, Borcherds, Wade, Poosapati, Anusha, Shammas, Sarah L, Daughdrill, Gary W, Clarke, Jane
Published in Biochemistry (Easton) (09.05.2017)
Published in Biochemistry (Easton) (09.05.2017)
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Journal Article
Role of non-native electrostatic interactions in the coupled folding and binding of PUMA with Mcl-1
Chu, Wen-Ting, Clarke, Jane, Shammas, Sarah L, Wang, Jin
Published in PLoS computational biology (01.04.2017)
Published in PLoS computational biology (01.04.2017)
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Journal Article
Two Differential Binding Mechanisms of FG-Nucleoporins and Nuclear Transport Receptors
Tan, Piau Siong, Aramburu, Iker Valle, Mercadante, Davide, Tyagi, Swati, Chowdhury, Aritra, Spitz, Daniel, Shammas, Sarah L., Gräter, Frauke, Lemke, Edward A.
Published in Cell reports (Cambridge) (27.03.2018)
Published in Cell reports (Cambridge) (27.03.2018)
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Journal Article
Separating the effects of internal friction and transition state energy to explain the slow, frustrated folding of spectrin domains
Wensley, Beth G, Kwa, Lee Gyan, Shammas, Sarah L, Rogers, Joseph M, Browning, Stuart, Yang, Ziqi, Clarke, Jane
Published in Proceedings of the National Academy of Sciences - PNAS (30.10.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (30.10.2012)
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Journal Article
Insights into Coupled Folding and Binding Mechanisms from Kinetic Studies
Shammas, Sarah L., Crabtree, Michael D., Dahal, Liza, Wicky, Basile I.M., Clarke, Jane
Published in The Journal of biological chemistry (25.03.2016)
Published in The Journal of biological chemistry (25.03.2016)
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Journal Article
Hsp70 Inhibits the Nucleation and Elongation of Tau and Sequesters Tau Aggregates with High Affinity
Kundel, Franziska, De, Suman, Flagmeier, Patrick, Horrocks, Mathew H, Kjaergaard, Magnus, Shammas, Sarah L, Jackson, Sophie E, Dobson, Christopher M, Klenerman, David
Published in ACS chemical biology (16.03.2018)
Published in ACS chemical biology (16.03.2018)
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Journal Article
Binding and folding in transcriptional complexes
Smith, Ngaio C, Kuravsky, Mikhail, Shammas, Sarah L, Matthews, Jacqueline M
Published in Current opinion in structural biology (01.02.2021)
Published in Current opinion in structural biology (01.02.2021)
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