ERBB2 drives YAP activation and EMT-like processes during cardiac regeneration
Aharonov, Alla, Shakked, Avraham, Umansky, Kfir Baruch, Savidor, Alon, Genzelinakh, Alexander, Kain, David, Lendengolts, Daria, Revach, Or-Yam, Morikawa, Yuka, Dong, Jixin, Levin, Yishai, Geiger, Benjamin, Martin, James F, Tzahor, Eldad
Published in Nature cell biology (01.11.2020)
Published in Nature cell biology (01.11.2020)
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Small-molecule inhibition of Lats kinases may promote Yap-dependent proliferation in postmitotic mammalian tissues
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Published in Nature communications (25.05.2021)
Published in Nature communications (25.05.2021)
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Single-cell analysis uncovers that metabolic reprogramming by ErbB2 signaling is essential for cardiomyocyte proliferation in the regenerating heart
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Published in eLife (23.12.2019)
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ERK1/2 inhibition promotes robust myotube growth via CaMKII activation resulting in myoblast-to-myotube fusion
Eigler, Tamar, Zarfati, Giulia, Amzallag, Emmanuel, Sinha, Sansrity, Segev, Nadav, Zabary, Yishaia, Zaritsky, Assaf, Shakked, Avraham, Umansky, Kfir-Baruch, Schejter, Eyal D., Millay, Douglas P., Tzahor, Eldad, Avinoam, Ori
Published in Developmental cell (20.12.2021)
Published in Developmental cell (20.12.2021)
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Lipid nanoparticles deliver mRNA to the blood–brain barrier
Kuzminich, Yanina, Shakked, Avraham, Calkins, Randi, Rudden, Sebastian, Jones, Camille, Doan, Jessie, Jang, Bora, Echeverri, Elisa Schrader, Zenhausern, Ryan, Lian, Liming, Loughrey, David, Peck, Hannah E., Wiese, Rachelle, Koveal, Dorothy, Santangelo, Philip J., Dahlman, James E.
Published in Nano research (01.08.2024)
Published in Nano research (01.08.2024)
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An enhancer-based gene-therapy strategy for spatiotemporal control of cargoes during tissue repair
Yan, Ruorong, Cigliola, Valentina, Oonk, Kelsey A., Petrover, Zachary, DeLuca, Sophia, Wolfson, David W., Vekstein, Andrew, Mendiola, Michelle A., Devlin, Garth, Bishawi, Muath, Gemberling, Matthew P., Sinha, Tanvi, Sargent, Michelle A., York, Allen J., Shakked, Avraham, DeBenedittis, Paige, Wendell, David C., Ou, Jianhong, Kang, Junsu, Goldman, Joseph A., Baht, Gurpreet S., Karra, Ravi, Williams, Adam R., Bowles, Dawn E., Asokan, Aravind, Tzahor, Eldad, Gersbach, Charles A., Molkentin, Jeffery D., Bursac, Nenad, Black, Brian L., Poss, Kenneth D.
Published in Cell stem cell (05.01.2023)
Published in Cell stem cell (05.01.2023)
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Interplay between calcium and sarcomeres directs cardiomyocyte maturation during regeneration
Nguyen, Phong D, Gooijers, Iris, Campostrini, Giulia, Verkerk, Arie O, Honkoop, Hessel, Bouwman, Mara, de Bakker, Dennis E M, Koopmans, Tim, Vink, Aryan, Lamers, Gerda E M, Shakked, Avraham, Mars, Jonas, Mulder, Aat A, Chocron, Sonja, Bartscherer, Kerstin, Tzahor, Eldad, Mummery, Christine L, de Boer, Teun P, Bellin, Milena, Bakkers, Jeroen
Published in Science (American Association for the Advancement of Science) (19.05.2023)
Published in Science (American Association for the Advancement of Science) (19.05.2023)
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Circuit to target approach defines an autocrine myofibroblast loop that drives cardiac fibrosis
Shoval Miyara, Adler, Miri, Bassat, Elad, Divinsky, Yalin, Kfir Baruch Umansky, Elkahal, Jacob, Genzelinakh, Alexander, Kain, David, Lendengolts, Daria, Shalit, Tali, Gershovits, Michael, Shakked, Avraham, Zhang, Lingling, Wang, Jingkui, Kimchi, Danielle Miriam, Baehr, Andrea, Sarig, Rachel, Kupatt, Christian, Tanaka, Elly Margaret, Medzhitov, Ruslan, Mayo, Avi, Alon, Uri, Tzahor, Eldad
Published in bioRxiv (03.01.2023)
Published in bioRxiv (03.01.2023)
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Redifferentiated cardiomyocytes retain residual dedifferentiation signatures and are protected against ischaemic injury
Shakked, Avraham, Petrover, Zachary, Aharonov, Alla, Ghiringhelli, Matteo, Kfir-Baruch Umansky, Phong Dang Nguyen, Kain, David, Elkahal, Jacob, Divinsky, Yalin, Shoval Miyara, Friedlander, Gilgi, Savidor, Alon, Zhang, Lingling, Perez, Dahlia, Kastan, Nathaniel, Lendengolts, Daria, Levin, Yishai, Bakkers, Jeroen, Gepstein, Lior, Tzahor, Eldad
Published in bioRxiv (22.02.2022)
Published in bioRxiv (22.02.2022)
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Paper
Small-molecule inhibition of Lats kinases promotes Yap-dependent proliferation in postmitotic mammalian tissues
Kastan, Nathaniel, Gnedeva, Ksenia, Alisch, Theresa, Petelski, Aleksandra, Huggins, David, Chiaravalli, Jeanne, Aharanov, Alla, Shakked, Avraham, Tzahor, Eldad, Nagiel, Aaron, Segil, Neil, Hudspeth, Albert J
Published in bioRxiv (12.02.2020)
Published in bioRxiv (12.02.2020)
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Paper
ERBB2 drives YAP activation and EMT-like processes during cardiac regeneration
Aharonov, Alla, Shakked, Avraham, Kfir Baruch Umansky, Savidor, Alon, Kain, David, Lendengolts, Daria, Or-Yam Revach, Morikawa, Yuka, Dong, Jixin, Levin, Yishai, Geiger, Benjamin, Martin, James F, Tzahor, Eldad
Published in bioRxiv (08.01.2020)
Published in bioRxiv (08.01.2020)
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A metabolic switch from OXPHOS to glycolysis is essential for cardiomyocyte proliferation in the regenerating heart
Hessel Honkoop, De Bakker, Dennis, Aharonov, Alla, Kruse, Fabian, Shakked, Avraham, Nguyen, Phong, De Heus, Cecilia, Garric, Laurence, Muraro, Mauro, Shoffner, Adam, Tessadori, Federico, Peterson, Joshua, Noort, Wendy, Posthuma, George, Grun, Dominic, Willem Van Der Laarse, Klumperman, Judith, Jaspers, Richard, Poss, Kenneth, Alexander Van Oudenaarden, Tzahor, Eldad, Bakkers, Jeroen
Published in bioRxiv (18.12.2018)
Published in bioRxiv (18.12.2018)
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