Interleukin-1β Maturation Triggers Its Relocation to the Plasma Membrane for Gasdermin-D-Dependent and -Independent Secretion
Monteleone, Mercedes, Stanley, Amanda C., Chen, Kaiwen W., Brown, Darren L., Bezbradica, Jelena S., von Pein, Jessica B., Holley, Caroline L., Boucher, Dave, Shakespear, Melanie R., Kapetanovic, Ronan, Rolfes, Verena, Sweet, Matthew J., Stow, Jennifer L., Schroder, Kate
Published in Cell reports (Cambridge) (07.08.2018)
Published in Cell reports (Cambridge) (07.08.2018)
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Class IIa Histone Deacetylases Drive Toll-like Receptor-Inducible Glycolysis and Macrophage Inflammatory Responses via Pyruvate Kinase M2
Das Gupta, Kaustav, Shakespear, Melanie R., Curson, James E.B., Murthy, Ambika M.V., Iyer, Abishek, Hodson, Mark P., Ramnath, Divya, Tillu, Vikas A., von Pein, Jessica B., Reid, Robert C., Tunny, Kathryn, Hohenhaus, Daniel M., Moradi, Shayli Varasteh, Kelly, Gregory M., Kobayashi, Takumi, Gunter, Jennifer H., Stevenson, Alexander J., Xu, Weijun, Luo, Lin, Jones, Alun, Johnston, Wayne A., Blumenthal, Antje, Alexandrov, Kirill, Collins, Brett M., Stow, Jennifer L., Fairlie, David P., Sweet, Matthew J.
Published in Cell reports (Cambridge) (25.02.2020)
Published in Cell reports (Cambridge) (25.02.2020)
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Histone deacetylases as regulators of inflammation and immunity
Shakespear, Melanie R, Halili, Maria A, Irvine, Katharine M, Fairlie, David P, Sweet, Matthew J
Published in Trends in immunology (01.07.2011)
Published in Trends in immunology (01.07.2011)
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Lysine Deacetylases and Regulated Glycolysis in Macrophages
Shakespear, Melanie R., Iyer, Abishek, Cheng, Catherine Youting, Das Gupta, Kaustav, Singhal, Amit, Fairlie, David P., Sweet, Matthew J.
Published in Trends in immunology (01.06.2018)
Published in Trends in immunology (01.06.2018)
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Histone deacetylases in monocyte/macrophage development, activation and metabolism: refining HDAC targets for inflammatory and infectious diseases
Das Gupta, Kaustav, Shakespear, Melanie R, Iyer, Abishek, Fairlie, David P, Sweet, Matthew J
Published in Clinical & translational immunology (01.01.2016)
Published in Clinical & translational immunology (01.01.2016)
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HDAC7 is an immunometabolic switch triaging danger signals for engagement of antimicrobial versus inflammatory responses in macrophages
Das Gupta, Kaustav, Ramnath, Divya, von Pein, Jessica B, Curson, James E B, Wang, Yizhuo, Abrol, Rishika, Kakkanat, Asha, Moradi, Shayli Varasteh, Gunther, Kimberley S, Murthy, Ambika M V, Stocks, Claudia J, Kapetanovic, Ronan, Reid, Robert C, Iyer, Abishek, Ilka, Zoe C, Nauseef, William M, Plan, Manuel, Luo, Lin, Stow, Jennifer L, Schroder, Kate, Karunakaran, Denuja, Alexandrov, Kirill, Shakespear, Melanie R, Schembri, Mark A, Fairlie, David P, Sweet, Matthew J
Published in Proceedings of the National Academy of Sciences - PNAS (24.01.2023)
Published in Proceedings of the National Academy of Sciences - PNAS (24.01.2023)
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Inhibition of Histone Deacetylases Permits Lipopolysaccharide-Mediated Secretion of Bioactive IL-1β via a Caspase-1-Independent Mechanism
Stammler, Dominik, Eigenbrod, Tatjana, Menz, Sarah, Frick, Julia S, Sweet, Matthew J, Shakespear, Melanie R, Jantsch, Jonathan, Siegert, Isabel, Wölfle, Sabine, Langer, Julian D, Oehme, Ina, Schaefer, Liliana, Fischer, Andre, Knievel, Judith, Heeg, Klaus, Dalpke, Alexander H, Bode, Konrad A
Published in The Journal of immunology (1950) (01.12.2015)
Published in The Journal of immunology (1950) (01.12.2015)
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Histone Deacetylase 7 Promotes Toll-like Receptor 4-dependent Proinflammatory Gene Expression in Macrophages
Shakespear, Melanie R., Hohenhaus, Daniel M., Kelly, Greg M., Kamal, Nabilah A., Gupta, Praveer, Labzin, Larisa I., Schroder, Kate, Garceau, Valerie, Barbero, Sheila, Iyer, Abishek, Hume, David A., Reid, Robert C., Irvine, Katharine M., Fairlie, David P., Sweet, Matthew J.
Published in The Journal of biological chemistry (30.08.2013)
Published in The Journal of biological chemistry (30.08.2013)
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