Modelling the Tox21 10 K chemical profiles for in vivo toxicity prediction and mechanism characterization
Huang, Ruili, Xia, Menghang, Sakamuru, Srilatha, Zhao, Jinghua, Shahane, Sampada A, Attene-Ramos, Matias, Zhao, Tongan, Austin, Christopher P, Simeonov, Anton
Published in Nature communications (26.01.2016)
Published in Nature communications (26.01.2016)
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Journal Article
Small Molecule Inhibitor of NRF2 Selectively Intervenes Therapeutic Resistance in KEAP1-Deficient NSCLC Tumors
Singh, Anju, Venkannagari, Sreedhar, Oh, Kyu H, Zhang, Ya-Qin, Rohde, Jason M, Liu, Li, Nimmagadda, Sridhar, Sudini, Kuladeep, Brimacombe, Kyle R, Gajghate, Sachin, Ma, Jinfang, Wang, Amy, Xu, Xin, Shahane, Sampada A, Xia, Menghang, Woo, Juhyung, Mensah, George A, Wang, Zhibin, Ferrer, Marc, Gabrielson, Edward, Li, Zhuyin, Rastinejad, Fraydoon, Shen, Min, Boxer, Matthew B, Biswal, Shyam
Published in ACS chemical biology (18.11.2016)
Published in ACS chemical biology (18.11.2016)
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Journal Article
Identification of genotoxic compounds using isogenic DNA repair deficient DT40 cell lines on a quantitative high throughput screening platform
Nishihara, Kana, Huang, Ruili, Zhao, Jinghua, Shahane, Sampada A, Witt, Kristine L, Smith-Roe, Stephanie L, Tice, Raymond R, Takeda, Shunichi, Xia, Menghang
Published in Mutagenesis (01.01.2016)
Published in Mutagenesis (01.01.2016)
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Journal Article
A new homogeneous high-throughput screening assay for profiling compound activity on the human ether-a-go-go-related gene channel
Titus, Steven A., Beacham, Daniel, Shahane, Sampada A., Southall, Noel, Xia, Menghang, Huang, Ruili, Hooten, Elizabeth, Zhao, Yong, Shou, Louie, Austin, Christopher P., Zheng, Wei
Published in Analytical biochemistry (01.11.2009)
Published in Analytical biochemistry (01.11.2009)
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Journal Article
Identification of novel PARP inhibitors using a cell-based TDP1 inhibitory assay in a quantitative high-throughput screening platform
Murai, Junko, Marchand, Christophe, Shahane, Sampada A., Sun, Hongmao, Huang, Ruili, Zhang, Yiping, Chergui, Adel, Ji, Jiuping, Doroshow, James H., Jadhav, Ajit, Takeda, Shunichi, Xia, Menghang, Pommier, Yves
Published in DNA repair (01.09.2014)
Published in DNA repair (01.09.2014)
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Journal Article
Tox21Challenge to Build Predictive Models of Nuclear Receptor and Stress Response Pathways as Mediated by Exposure to Environmental Chemicals and Drugs
Huang, Ruili, Xia, Menghang, Nguyen, Dac-Trung, Zhao, Tongan, Sakamuru, Srilatha, Zhao, Jinghua, Shahane, Sampada A, Rossoshek, Anna, Simeonov, Anton
Published in Frontiers in environmental science (14.01.2016)
Published in Frontiers in environmental science (14.01.2016)
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Journal Article
Identification of quaternary ammonium compounds as potent inhibitors of hERG potassium channels
Xia, Menghang, Shahane, Sampada A., Huang, Ruili, Titus, Steven A., Shum, Enoch, Zhao, Yong, Southall, Noel, Zheng, Wei, Witt, Kristine L., Tice, Raymond R., Austin, Christopher P.
Published in Toxicology and applied pharmacology (01.05.2011)
Published in Toxicology and applied pharmacology (01.05.2011)
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Journal Article
Inhibition of Morphine-Induced cAMP Overshoot: A Cell-Based Assay Model in a High-Throughput Format
Xia, Menghang, Guo, Vicky, Huang, Ruili, Shahane, Sampada A., Austin, Christopher P., Nirenberg, Marshall, Sharma, Shail K.
Published in Cellular and molecular neurobiology (01.08.2011)
Published in Cellular and molecular neurobiology (01.08.2011)
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Journal Article
Are hERG channel blockers also phospholipidosis inducers?
Sun, Hongmao, Xia, Menghang, Shahane, Sampada A., Jadhav, Ajit, Austin, Christopher P., Huang, Ruili
Published in Bioorganic & medicinal chemistry letters (15.08.2013)
Published in Bioorganic & medicinal chemistry letters (15.08.2013)
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