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Published in Nature (London) (08.06.2000)
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Presenilin 1 Is Linked with γ -Secretase Activity in the Detergent Solubilized State
Li, Yue-Ming, Lai, Ming-Tain, Xu, Min, Huang, Qian, DiMuzio-Mower, Jillian, Sardana, Mohinder K., Shi, Xiao-Ping, Yin, Kuo-Chang, Shafer, Jules A., Gardell, Stephen J.
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Published in Proceedings of the National Academy of Sciences - PNAS (23.05.2000)
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Pharmacokinetic optimization of 3-amino-6-chloropyrazinone acetamide thrombin inhibitors. implementation of P3 pyridine N-Oxides to deliver an orally bioavailable series containing P1 N-Benzylamides
Burgey, Christopher S., Robinson, Kyle A., Lyle, Terry A., Nantermet, Philippe G., Selnick, Harold G., Isaacs, Richard C.A., Lewis, S.Dale, Lucas, Bobby J., Krueger, Julie A., Singh, Rominder, Miller-Stein, Cynthia, White, Rebecca B., Wong, Bradley, Lyle, Elizabeth A., Stranieri, Maria T., Cook, Jacquelynn J., McMasters, Daniel R., Pellicore, Janetta M., Pal, Swati, Wallace, Audrey A., Clayton, Franklin C., Bohn, Dennis, Welsh, Denise C., Lynch, Joseph J., Yan, Youwei, Chen, Zhongguo, Kuo, Lawrence, Gardell, Stephen J., Shafer, Jules A., Vacca, Joseph P.
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Published in Bioorganic & medicinal chemistry letters (07.04.2003)
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γ-Secretase: characterization and implication for Alzheimer disease therapy
MIN XU, LAI, Ming-Tain, GARDELL, Stephen J, LI, Yue-Ming, QIAN HUANG, DIMUZIO-MOWER, Jillian, CASTRO, José L, HARRISON, Timothy, NADIN, Alan, NEDUVELIL, Joseph G, SHEARMAN, Mark S, SHAFER, Jules A
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Published in Neurobiology of aging (01.11.2002)
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P2 pyridine N-oxide thrombin inhibitors : a novel peptidomimetic scaffold
NANTERMET, Philippe G, BURGEY, Christopher S, MILLER-STEIN, Cynthia, WHITE, Rebecca B, WONG, Bradley, MCMASTERS, Daniel R, WALLACE, Audrey A, LYNCH, Joseph J, YOUWEI YAN, ZHONGGUO CHEN, KUO, Lawrence, GARDELL, Stephen J, ROBINSON, Kyle A, SHAFER, Jules A, VACCA, Joseph P, LYLE, Terry A, PELLICORE, Janetta M, NEWTON, Christina L, DENG, James Z, SELNICK, Harold G, LEWIS, S. Dale, LUCAS, Bobby J, KRUEGER, Julie A
Published in Bioorganic & medicinal chemistry letters (02.06.2005)
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An antibody against the exosite of the cloned thrombin receptor inhibits experimental arterial thrombosis in the African green monkey
COOK, J. J, SITKO, G. R, BEDNAR, B, CONDRA, C, MELLOTT, M. J, DONG-MEI FENG, NUTT, R. F, SHAFER, J. A, GOULD, R. J, CONNOLLY, T. M
Published in Circulation (New York, N.Y.) (15.06.1995)
Published in Circulation (New York, N.Y.) (15.06.1995)
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Isoprenoid diphosphate utilization by recombinant human farnesyl:protein transferase: Interactive binding between substrates and a preferred kinetic pathway
Pompliano, David L, Schaber, Michael D, Mosser, Scott D, Omer, Charles A, Shafer, Jules A, Gibbs, Jackson B
Published in Biochemistry (Easton) (17.08.1993)
Published in Biochemistry (Easton) (17.08.1993)
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Dissociation and association of the HIV-1 protease dimer subunits: Equilibria and rates
Darke, Paul L, Hall, Dawn L, Jordan, Susan P, Zugay, Joan A, Shafer, Jules A, Kuo, Lawrence C
Published in Biochemistry (Easton) (11.01.1994)
Published in Biochemistry (Easton) (11.01.1994)
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Reactivity of small thiolate anions and cysteine-25 in papain toward methyl methanethiosulfonate
Roberts, David D, Lewis, Sidney D, Ballou, David P, Olson, Steven T, Shafer, Jules A
Published in Biochemistry (Easton) (23.09.1986)
Published in Biochemistry (Easton) (23.09.1986)
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Reaction pathway for inhibition of blood coagulation factor Xa by tick anticoagulant peptide
Jordan, Susan P, Mao, Shi Shan, Lewis, Sidney D, Shafer, Jules A
Published in Biochemistry (Easton) (16.06.1992)
Published in Biochemistry (Easton) (16.06.1992)
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Solution oligomerization of the rev protein of HIV-1: Implications for function
Cole, James L, Gehman, John D, Shafer, Jules A, Kuo, Lawrence C
Published in Biochemistry (Easton) (09.11.1993)
Published in Biochemistry (Easton) (09.11.1993)
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Identification of Low Molecular Weight GP IIb/IIIa Antagonists That Bind Preferentially to Activated Platelets
Bednar, R A, Gaul, S L, Hamill, T G, Egbertson, M S, Shafer, J A, Hartman, G D, Gould, R J, Bednar, B
Published in The Journal of pharmacology and experimental therapeutics (01.06.1998)
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Published in The Journal of pharmacology and experimental therapeutics (01.06.1998)
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Identification and Characterization of Variants of Tick Anticoagulant Peptide with Increased Inhibitory Potency toward Human Factor Xa
Mao, Shi-Shan, Huang, Jin, Welebob, Carolee, Neeper, Michael P, Garsky, Victor M, Shafer, Jules A
Published in Biochemistry (Easton) (18.04.1995)
Published in Biochemistry (Easton) (18.04.1995)
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Regulation of the formation of factor XIIIa by its fibrin substrates
Lewis, Sidney D, Janus, Todd J, Lorand, Laszlo, Shafer, Jules A
Published in Biochemistry (Easton) (19.11.1985)
Published in Biochemistry (Easton) (19.11.1985)
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