Tandem Mass Spectrometry Multiplex Analysis of Glucosylceramide and Galactosylceramide Isoforms in Brain Tissues at Different Stages of Parkinson Disease
Boutin, Michel, Sun, Ying, Shacka, John J, Auray-Blais, Christiane
Published in Analytical chemistry (Washington) (02.02.2016)
Published in Analytical chemistry (Washington) (02.02.2016)
Get full text
Journal Article
MHCII is required for α-synuclein-induced activation of microglia, CD4 T cell proliferation, and dopaminergic neurodegeneration
Harms, Ashley S, Cao, Shuwen, Rowse, Amber L, Thome, Aaron D, Li, Xinru, Mangieri, Leandra R, Cron, Randy Q, Shacka, John J, Raman, Chander, Standaert, David G
Published in The Journal of neuroscience (05.06.2013)
Published in The Journal of neuroscience (05.06.2013)
Get full text
Journal Article
Restoration of CTSD (cathepsin D) and lysosomal function in stroke is neuroprotective
Hossain, M. Iqbal, Marcus, Joshua M., Lee, Jun Hee, Garcia, Patrick L., Singh, VinodKumar, Shacka, John J., Zhang, Jianhua, Gropen, Toby I., Falany, Charles N., Andrabi, Shaida A.
Published in Autophagy (03.06.2021)
Published in Autophagy (03.06.2021)
Get full text
Journal Article
The lysosomal enzyme alpha-Galactosidase A is deficient in Parkinson's disease brain in association with the pathologic accumulation of alpha-synuclein
Nelson, Michael P., Boutin, Michel, Tse, Tonia E., Lu, Hailin, Haley, Emily D., Ouyang, Xiaosen, Zhang, Jianhua, Auray-Blais, Christiane, Shacka, John J.
Published in Neurobiology of disease (01.02.2018)
Published in Neurobiology of disease (01.02.2018)
Get full text
Journal Article
ATP6V0C knockdown in neuroblastoma cells alters autophagy-lysosome pathway function and metabolism of proteins that accumulate in neurodegenerative disease
Mangieri, Leandra R, Mader, Burton J, Thomas, Cailin E, Taylor, Charles A, Luker, Austin M, Tse, Tonia E, Huisingh, Carrie, Shacka, John J
Published in PloS one (01.04.2014)
Published in PloS one (01.04.2014)
Get full text
Journal Article
O-GlcNAc regulation of autophagy and α-synuclein homeostasis; implications for Parkinson's disease
Wani, Willayat Y, Ouyang, Xiaosen, Benavides, Gloria A, Redmann, Matthew, Cofield, Stacey S, Shacka, John J, Chatham, John C, Darley-Usmar, Victor, Zhang, Jianhua
Published in Molecular brain (19.07.2017)
Published in Molecular brain (19.07.2017)
Get full text
Journal Article
HIV-1 and morphine regulation of autophagy in microglia: limited interactions in the context of HIV-1 infection and opioid abuse
El-Hage, Nazira, Rodriguez, Myosotys, Dever, Seth M, Masvekar, Ruturaj R, Gewirtz, David A, Shacka, John J
Published in Journal of virology (15.01.2015)
Published in Journal of virology (15.01.2015)
Get full text
Journal Article
Brief Report: Intracellular Cystatin B Levels Are Altered in HIV-Infected Participants With Respect to Neurocognitive Status and Antiretroviral Therapy
Opsteen, Skye, Moylan, David, Taiwo, Babafemi O, Robertson, Kevin R, Overton, E Turner, Cutter, Gary R, Sabbaj, Steffanie, Heath, Sonya L, Shacka, John J
Published in Journal of acquired immune deficiency syndromes (1999) (15.12.2022)
Published in Journal of acquired immune deficiency syndromes (1999) (15.12.2022)
Get more information
Journal Article
Oxidative stress and autophagy in the regulation of lysosome-dependent neuron death
Pivtoraiko, Violetta N, Stone, Sara L, Roth, Kevin A, Shacka, John J
Published in Antioxidants & redox signaling (01.03.2009)
Published in Antioxidants & redox signaling (01.03.2009)
Get more information
Journal Article
Lysosomal enzyme cathepsin D protects against alpha-synuclein aggregation and toxicity
Qiao, Liyan, Hamamichi, Shusei, Caldwell, Kim A, Caldwell, Guy A, Yacoubian, Talene A, Wilson, Scott, Xie, Zuo-Lei, Speake, Lisa D, Parks, Rachael, Crabtree, Donna, Liang, Qiuli, Crimmins, Stephen, Schneider, Lonnie, Uchiyama, Yasuo, Iwatsubo, Takeshi, Zhou, Yi, Peng, Lisheng, Lu, YouMing, Standaert, David G, Walls, Ken C, Shacka, John J, Roth, Kevin A, Zhang, Jianhua
Published in Molecular brain (21.11.2008)
Published in Molecular brain (21.11.2008)
Get full text
Journal Article
HIV-Specific CD8+ T Cells from Elite Controllers Are Primed for Survival
Yan, Jiyu, Sabbaj, Steffanie, Bansal, Anju, Amatya, Nilesh, Shacka, John J, Goepfert, Paul A, Heath, Sonya L
Published in Journal of Virology (01.05.2013)
Published in Journal of Virology (01.05.2013)
Get full text
Journal Article
Rotenone Inhibits Autophagic Flux Prior to Inducing Cell Death
Mader, Burton J, Pivtoraiko, Violetta N, Flippo, Hilary M, Klocke, Barbara J, Roth, Kevin A, Mangieri, Leandra R, Shacka, John J
Published in ACS chemical neuroscience (19.12.2012)
Published in ACS chemical neuroscience (19.12.2012)
Get full text
Journal Article
Kainic acid induces early and transient autophagic stress in mouse hippocampus
Shacka, John J., Lu, Jun, Xie, Zuo-Lei, Uchiyama, Yasuo, Roth, Kevin A., Zhang, Jianhua
Published in Neuroscience letters (27.02.2007)
Published in Neuroscience letters (27.02.2007)
Get full text
Journal Article
Lysosome Dysfunction Triggers Atg7-dependent Neural Apoptosis
Walls, Ken C., Ghosh, Arindam P., Franklin, Aimee V., Klocke, Barbara J., Ballestas, Mary, Shacka, John J., Zhang, Jianhua, Roth, Kevin A.
Published in The Journal of biological chemistry (02.04.2010)
Published in The Journal of biological chemistry (02.04.2010)
Get full text
Journal Article
Tristetraprolin down-regulates interleukin-8 and vascular endothelial growth factor in malignant glioma cells
Suswam, Esther, Li, Yanyan, Zhang, Xiaowen, Gillespie, G Yancey, Li, Xuelin, Shacka, John J, Lu, Liang, Zheng, Lei, King, Peter H
Published in Cancer research (Chicago, Ill.) (01.02.2008)
Published in Cancer research (Chicago, Ill.) (01.02.2008)
Get full text
Journal Article
Bafilomycin A1 Inhibits Chloroquine-Induced Death of Cerebellar Granule Neurons
Shacka, John J, Klocke, Barbara J, Shibata, Masahiro, Uchiyama, Yasuo, Datta, Geeta, Schmidt, Robert E, Roth, Kevin A
Published in Molecular pharmacology (01.04.2006)
Published in Molecular pharmacology (01.04.2006)
Get full text
Journal Article