An Advanced Apralog with Increased in vitro and in vivo Activity toward Gram‐negative Pathogens and Reduced ex vivo Cochleotoxicity
Sonousi, Amr, Quirke, Jonathan C. K., Waduge, Prabuddha, Janusic, Tanja, Gysin, Marina, Haldimann, Klara, Xu, Shan, Hobbie, Sven N., Sha, Su‐Hua, Schacht, Jochen, Chow, Christine S., Vasella, Andrea, Böttger, Erik C., Crich, David
Published in ChemMedChem (19.01.2021)
Published in ChemMedChem (19.01.2021)
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Journal Article
Dissociation of antibacterial activity and aminoglycoside ototoxicity in the 4-monosubstituted 2-deoxystreptamine apramycin
Matt, Tanja, Ng, Chyan Leong, Lang, Kathrin, Sha, Su-Hua, Akbergenov, Rashid, Shcherbakov, Dmitri, Meyer, Martin, Duscha, Stefan, Xie, Jing, Dubbaka, Srinivas R, Perez-Fernandez, Déborah, Vasella, Andrea, Ramakrishnan, V, Schacht, Jochen, Böttger, Erik C
Published in Proceedings of the National Academy of Sciences - PNAS (03.07.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (03.07.2012)
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Journal Article
Prevention of noise-induced hearing loss by calpain inhibitor MDL-28170 is associated with upregulation of PI3K/Akt survival signaling pathway
Lai, Ruosha, Fang, Qiaojun, Wu, Fan, Pan, Song, Haque, Khujista, Sha, Su-Hua
Published in Frontiers in cellular neuroscience (06.07.2023)
Published in Frontiers in cellular neuroscience (06.07.2023)
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Journal Article
CFTR potentiator ivacaftor protects against noise-induced hair cell loss by increasing Nrf2 and reducing oxidative stress
Wu, Fan, Hu, Rui, Huang, Xueping, Lou, Jintao, Cai, Ziyi, Chen, Guisheng, Zhao, Wenji, Xiong, Hao, Sha, Su-Hua, Zheng, Yiqing
Published in Biomedicine & pharmacotherapy (01.10.2023)
Published in Biomedicine & pharmacotherapy (01.10.2023)
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Journal Article
Inhibitors of Histone Deacetylases Attenuate Noise-Induced Hearing Loss
Chen, Jun, Hill, Kayla, Sha, Su-Hua
Published in Journal of the Association for Research in Otolaryngology (01.08.2016)
Published in Journal of the Association for Research in Otolaryngology (01.08.2016)
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Journal Article
Inhibition of Histone Methyltransferase G9a Attenuates Noise-Induced Cochlear Synaptopathy and Hearing Loss
Xiong, Hao, Long, Haishan, Pan, Song, Lai, Ruosha, Wang, Xianren, Zhu, Yuanping, Hill, Kayla, Fang, Qiaojun, Zheng, Yiqing, Sha, Su-Hua
Published in Journal of the Association for Research in Otolaryngology (01.06.2019)
Published in Journal of the Association for Research in Otolaryngology (01.06.2019)
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Journal Article
Traumatic noise activates Rho-family GTPases through transient cellular energy depletion
Chen, Fu-Quan, Zheng, Hong-Wei, Hill, Kayla, Sha, Su-Hua
Published in The Journal of neuroscience (05.09.2012)
Published in The Journal of neuroscience (05.09.2012)
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Journal Article
Mitochondrial Calcium Transporters Mediate Sensitivity to Noise-Induced Losses of Hair Cells and Cochlear Synapses
Wang, Xianren, Zhu, Yuanping, Long, Haishan, Pan, Song, Xiong, Hao, Fang, Qiaojun, Hill, Kayla, Lai, Ruosha, Yuan, Hu, Sha, Su-Hua
Published in Frontiers in molecular neuroscience (08.01.2019)
Published in Frontiers in molecular neuroscience (08.01.2019)
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Journal Article
Histone Deacetylase Inhibitors Are Protective in Acute but Not in Chronic Models of Ototoxicity
Yang, Chao-Hui, Liu, Zhiqi, Dong, Deanna, Schacht, Jochen, Arya, Dev, Sha, Su-Hua
Published in Frontiers in cellular neuroscience (24.10.2017)
Published in Frontiers in cellular neuroscience (24.10.2017)
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Journal Article
Aspirin to Prevent Gentamicin-Induced Hearing Loss
Qiu, Jian-Hua, Sha, Su-Hua, Schacht, Jochen
Published in The New England journal of medicine (27.04.2006)
Published in The New England journal of medicine (27.04.2006)
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Journal Article
Treatment With Calcineurin Inhibitor FK506 Attenuates Noise-Induced Hearing Loss
He, Zu-Hong, Pan, Song, Zheng, Hong-Wei, Fang, Qiao-Jun, Hill, Kayla, Sha, Su-Hua
Published in Frontiers in cell and developmental biology (12.03.2021)
Published in Frontiers in cell and developmental biology (12.03.2021)
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Journal Article
NF-κB pathway protects cochlear hair cells from aminoglycoside-induced ototoxicity
Jiang, Hongyan, Sha, Su-Hua, Schacht, Jochen
Published in Journal of neuroscience research (01.03.2005)
Published in Journal of neuroscience research (01.03.2005)
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Journal Article
Differential vulnerability of basal and apical hair cells is based on intrinsic susceptibility to free radicals
Sha, Su-Hua, Taylor, Ruth, Forge, Andrew, Schacht, Jochen
Published in Hearing research (01.05.2001)
Published in Hearing research (01.05.2001)
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Journal Article
Age-related auditory pathology in the CBA/J mouse
Sha, Su-Hua, Kanicki, Ariane, Dootz, Gary, Talaska, Andra E., Halsey, Karin, Dolan, David, Altschuler, Richard, Schacht, Jochen
Published in Hearing research (01.09.2008)
Published in Hearing research (01.09.2008)
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Journal Article