Discovery of Selective and Noncovalent Diaminopyrimidine-Based Inhibitors of Epidermal Growth Factor Receptor Containing the T790M Resistance Mutation
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Published in Journal of medicinal chemistry (11.12.2014)
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Published in Journal of medicinal chemistry (13.09.2012)
Published in Journal of medicinal chemistry (13.09.2012)
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Discovery of a Noncovalent, Mutant-Selective Epidermal Growth Factor Receptor Inhibitor
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Published in Journal of medicinal chemistry (13.10.2016)
Published in Journal of medicinal chemistry (13.10.2016)
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Discovery of Novel PI3-Kinase δ Specific Inhibitors for the Treatment of Rheumatoid Arthritis: Taming CYP3A4 Time-Dependent Inhibition
Safina, Brian S, Baker, Stewart, Baumgardner, Matt, Blaney, Paul M, Chan, Bryan K, Chen, Yung-Hsiang, Cartwright, Matthew W, Castanedo, Georgette, Chabot, Christine, Cheguillaume, Arnaud J, Goldsmith, Paul, Goldstein, David M, Goyal, Bindu, Hancox, Timothy, Handa, Raj K, Iyer, Pravin S, Kaur, Jasmit, Kondru, Rama, Kenny, Jane R, Krintel, Sussie L, Li, Jun, Lesnick, John, Lucas, Matthew C, Lewis, Cristina, Mukadam, Sophie, Murray, Jeremy, Nadin, Alan J, Nonomiya, Jim, Padilla, Fernando, Palmer, Wylie S, Pang, Jodie, Pegg, Neil, Price, Steve, Reif, Karin, Salphati, Laurent, Savy, Pascal A, Seward, Eileen M, Shuttleworth, Stephen, Sohal, Sukhjit, Sweeney, Zachary K, Tay, Suzanne, Tivitmahaisoon, Parcharee, Waszkowycz, Bohdan, Wei, Binqing, Yue, Qin, Zhang, Chenghong, Sutherlin, Daniel P
Published in Journal of medicinal chemistry (28.06.2012)
Published in Journal of medicinal chemistry (28.06.2012)
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Design of Selective Benzoxazepin PI3Kδ Inhibitors Through Control of Dihedral Angles
Safina, Brian S, Elliott, Richard L, Forrest, Andrew K, Heald, Robert A, Murray, Jeremy M, Nonomiya, Jim, Pang, Jodie, Salphati, Laurent, Seward, Eileen M, Staben, Steven T, Ultsch, Mark, Wei, Binqing, Yang, Wenqian, Sutherlin, Daniel P
Published in ACS medicinal chemistry letters (14.09.2017)
Published in ACS medicinal chemistry letters (14.09.2017)
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Identification of GNE-293, a potent and selective PI3Kδ inhibitor: Navigating in vitro genotoxicity while improving potency and selectivity
Safina, Brian S., Sweeney, Zachary K., Li, Jun, Chan, Bryan K., Bisconte, Angelina, Carrera, Diane, Castanedo, Georgette, Flagella, Michael, Heald, Robert, Lewis, Cristina, Murray, Jeremy M., Nonomiya, Jim, Pang, Jodie, Price, Steve, Reif, Karin, Salphati, Laurent, Seward, Eileen M., Wei, Binqing, Sutherlin, Daniel P.
Published in Bioorganic & medicinal chemistry letters (01.09.2013)
Published in Bioorganic & medicinal chemistry letters (01.09.2013)
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Potent and selective inhibitors of PI3Kδ: Obtaining isoform selectivity from the affinity pocket and tryptophan shelf
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Published in Bioorganic & medicinal chemistry letters (01.07.2012)
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Substituent Effects on Edge-to-Face Aromatic Interactions
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Published in Chemistry : a European journal (03.07.2002)
Published in Chemistry : a European journal (03.07.2002)
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유로리틴 유도체 및 이의 사용 방법
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Year of Publication 06.11.2023
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Redox-dependent binding ability of a flavin cyclophane in aqueous solution: hydrophobic stacking versus cavity-inclusion complexation
Seward, Eileen M, Hopkins, R. Bruce, Sauerer, Wolfgang, Tam, Suk Wah, Diederich, Francois
Published in Journal of the American Chemical Society (01.02.1990)
Published in Journal of the American Chemical Society (01.02.1990)
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Spirocyclic NK1 antagonists I:[4.5] and [5.5]-spiroketals
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Published in Bioorganic & medicinal chemistry letters (16.09.2002)
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AMINOPYRIMIDINE COMPOUNDS AS INHIBITORS OF T790M CONTAINING EGFR MUTANTS
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SAFINA BRIAN, SUTHERLIN DANIEL P, PRICE STEPHEN, SEWARD EILEEN M, SAVY PASCAL PIERRE ALEXANDRE, WASZKOWYCZ BOHDAN, HEALD ROBERT
Year of Publication 23.10.2013
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Year of Publication 23.10.2013
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Year of Publication 14.03.2014
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Year of Publication 14.03.2014
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Synthesis, X-ray crystal structures, and cation transfer properties of alkyl calixaryl acetates, a new series of molecular receptors
MCKERVEY, M. A, SEWARD, E. M, FERGUSON, G, RUHL, B, HARRIS, S. J
Published in Journal of the Chemical Society. Chemical communications (1985)
Published in Journal of the Chemical Society. Chemical communications (1985)
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Cation complexation by chemically modified calixarenes. Part 7. Transport of alkali cations by p-tert-butylcalix[n]arene esters and amides
Arnaud-Neu, Fran oise, Fanni, Stefano, Guerra, Lourdes, McGregor, William, Ziat, Khadija, Schwing-Weill, Marie-Jos, Barrett, Geraldine, McKervey, M. Anthony, Marrs, Deborah, Seward, Eileen M.
Published in Journal of the Chemical Society, Perkin Transactions 2 (1995)
Published in Journal of the Chemical Society, Perkin Transactions 2 (1995)
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