Discovery of CC-90011: A Potent and Selective Reversible Inhibitor of Lysine Specific Demethylase 1 (LSD1)
Kanouni, Toufike, Severin, Christophe, Cho, Robert W, Yuen, Natalie Y.-Y, Xu, Jiangchun, Shi, Lihong, Lai, Chon, Del Rosario, Joselyn R, Stansfield, Ryan K, Lawton, Lee N, Hosfield, David, O’Connell, Shawn, Kreilein, Matt M, Tavares-Greco, Paula, Nie, Zhe, Kaldor, Stephen W, Veal, James M, Stafford, Jeffrey A, Chen, Young K
Published in Journal of medicinal chemistry (10.12.2020)
Published in Journal of medicinal chemistry (10.12.2020)
Get full text
Journal Article
Somatic mutations lead to an oncogenic deletion of met in lung cancer
KONG-BELTRAN, Monica, SESHAGIRI, Somasekar, SEVERIN, Christophe, RANGELL, Linda, SCHWALL, Ralph, AMLER, Lukas, WICKRAMASINGHE, Dineli, YAUCH, Robert, JIPING ZHA, WENJING ZHU, BHAWE, Kaumudi, MENDOZA, Nerissa, HOLCOMB, Thomas, PUJARA, Kanan, STINSON, Jeremy, LING FU
Published in Cancer research (Chicago, Ill.) (2006)
Published in Cancer research (Chicago, Ill.) (2006)
Get full text
Journal Article
Retinal axon growth cones respond to EphB extracellular domains as inhibitory axon guidance cues
Birgbauer, E, Oster, S F, Severin, C G, Sretavan, D W
Published in Development (Cambridge) (01.08.2001)
Published in Development (Cambridge) (01.08.2001)
Get full text
Journal Article
DDRE-26. TARGETING THE UNFOLDED PROTEIN RESPONSE POTENTIATES MARIZOMIB ANTITUMOR ACTIVITY IN GLIOBLASTOMA
Severin, Christophe, Benitez-Hernandez, Jorge, Dumitru, C Dan, Beltran-Raygoza, Nishdallyh, Flandin-Blety, Pierre, Escoubet, Laure, Rolfe, Mark
Published in Neuro-oncology (Charlottesville, Va.) (09.11.2020)
Published in Neuro-oncology (Charlottesville, Va.) (09.11.2020)
Get full text
Journal Article
Structure-based design and discovery of potent and selective lysine-specific demethylase 1 (LSD1) inhibitors
Nie, Zhe, Shi, Lihong, Lai, Chon, Severin, Christophe, Xu, Jiangchun, Del Rosario, Joselyn R., Stansfield, Ryan K., Cho, Robert W., Kanouni, Toufike, Veal, James M., Stafford, Jeffrey A., Chen, Young K.
Published in Bioorganic & medicinal chemistry letters (01.01.2019)
Published in Bioorganic & medicinal chemistry letters (01.01.2019)
Get full text
Journal Article
Nonclinical evaluation of the serum pharmacodynamic biomarkers HGF and shed MET following dosing with the anti-MET monovalent monoclonal antibody onartuzumab
Mai, Elaine, Zheng, Zhong, Chen, Youjun, Peng, Jing, Severin, Christophe, Filvaroff, Ellen, Romero, Mally, Mallet, William, Kaur, Surinder, Gelzleichter, Thomas, Nijem, Ihsan, Merchant, Mark, Young, Judy C
Published in Molecular cancer therapeutics (01.02.2014)
Published in Molecular cancer therapeutics (01.02.2014)
Get full text
Journal Article