Acquired Resistance of EGFR-Mutated Lung Cancer to Tyrosine Kinase Inhibitor Treatment Promotes PARP Inhibitor Sensitivity
Marcar, Lynnette, Bardhan, Kankana, Gheorghiu, Liliana, Dinkelborg, Patrick, Pfäffle, Heike, Liu, Qi, Wang, Meng, Piotrowska, Zofia, Sequist, Lecia V., Borgmann, Kerstin, Settleman, Jeffrey E., Engelman, Jeffrey A., Hata, Aaron N., Willers, Henning
Published in Cell reports (Cambridge) (18.06.2019)
Published in Cell reports (Cambridge) (18.06.2019)
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A Phase I Study of Erlotinib and Hydroxychloroquine in Advanced Non–Small-Cell Lung Cancer
Goldberg, Sarah B., Supko, Jeffrey G., Neal, Joel W., Muzikansky, Alona, Digumarthy, Subba, Fidias, Panos, Temel, Jennifer S., Heist, Rebecca S., Shaw, Alice T., McCarthy, Patricia O., Lynch, Thomas J., Sharma, Sreenath, Settleman, Jeffrey E., Sequist, Lecia V.
Published in Journal of thoracic oncology (01.10.2012)
Published in Journal of thoracic oncology (01.10.2012)
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Coordination of Rho and Rac GTPase Function via p190B RhoGAP
Bustos, Rodrigo I., Forget, Marie-Annick, Settleman, Jeffrey E., Hansen, Steen H.
Published in Current biology (28.10.2008)
Published in Current biology (28.10.2008)
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Discovery of a benzo[e]pyrimido-[5,4-b][1,4]diazepin-6(11H)-one as a Potent and Selective Inhibitor of Big MAP Kinase 1
Deng, Xianming, Yang, Qingkai, Kwiatkowski, Nicholas, Sim, Taebo, McDermott, Ultan, Settleman, Jeffrey E, Lee, Jiing-Dwan, Gray, Nathanael S
Published in ACS medicinal chemistry letters (10.03.2011)
Published in ACS medicinal chemistry letters (10.03.2011)
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Sunitinib prolongs survival in genetically engineered mouse models of multistep lung carcinogenesis
Gandhi, Leena, McNamara, Kate L, Li, Danan, Borgman, Christa L, McDermott, Ultan, Brandstetter, Kathleyn A, Padera, Robert F, Chirieac, Lucian R, Settleman, Jeffrey E, Wong, Kwok-Kin
Published in Cancer prevention research (Philadelphia, Pa.) (01.04.2009)
Published in Cancer prevention research (Philadelphia, Pa.) (01.04.2009)
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Journal Article
Case 23-2008: A 26-Year-Old Man with Back Pain and a Mass in the Lung
Sequist, Lecia V, Settleman, Jeffrey E, Ackman, Jeanne B, Iafrate, A. John
Published in The New England journal of medicine (24.07.2008)
Published in The New England journal of medicine (24.07.2008)
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METHODS FOR DETERMINING CANCER RESPONSIVENESS TO TREATMENTS TARGETING EPITHELIAL CELL GROWTH FACTOR RECEPTOR
HABER DANIEL A, JOHNSON BRUCE E, PAEZ JUAN GUILLERMO, LYNCH THOMAS J, SELLERS WILLIAM R, SETTLEMAN JEFFREY E, JANNE PASI ANTERO, BELL DAPHNE WINIFRED, SORDELLA RAFFAELLA, MEYERSON MATTHEW
Year of Publication 20.04.2017
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Year of Publication 20.04.2017
Patent
METHOD FOR DETERMINING RESPONSIVENESS OF CANCER TO EPIDERMAL GROWTH FACTOR RECEPTOR TARGETING TREATMENTS
HABER DANIEL A, JOHNSON BRUCE E, PAEZ JUAN GUILLERMO, LYNCH THOMAS J, SELLERS WILLIAM R, SETTLEMAN JEFFREY E, JANNE PASI ANTERO, BELL DAPHNE WINIFRED, SORDELLA RAFFAELLA, MEYERSON MATTHEW
Year of Publication 05.02.2015
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Year of Publication 05.02.2015
Patent
METHOD FOR DETERMINING THE LIKELIHOOD OF EFFECTIVENESS OF AN EPIDERMAL GROWTH FACTOR RECEPTOR TARGETING TREATMENT IN A HUMAN PATIENT AFFECTED WITH CANCER, KIT, NUCLEIC ACID PROBE, PRIMER PAIR, AND ISOLATED PROTEIN
HABER DANIEL A, JOHNSON BRUCE E, PAEZ JUAN GUILLERMO, LYNCH THOMAS J, SELLERS WILLIAM R, SETTLEMAN JEFFREY E, JANNE PASI ANTERO, BELL DAPHNE WINIFRED, SORDELLA RAFFAELLA, MEYERSON MATTHEW
Year of Publication 21.01.2013
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Year of Publication 21.01.2013
Patent
METHOD TO DETERMINE RESPONSIVENESS OF CANCER TO EPIDERMAL GROWTH FACTOR RECEPTOR TARGETING TREATMENTS
HABER DANIEL A, JOHNSON BRUCE E, PAEZ JUAN GUILLERMO, LYNCH THOMAS J, SELLERS WILLIAM R, SETTLEMAN JEFFREY E, JANNE PASI ANTERO, BELL DAPHNE WINIFRED, SORDELLA RAFFAELLA, MEYERSON MATTHEW
Year of Publication 07.08.2012
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Year of Publication 07.08.2012
Patent
Abstract 5754: Identification of pharmacologically tractable genes that are associated with oncogenic K-Ras dependency in colorectal cancers
Singh, Anurag, Sweeney, Michael F., Greninger, Patricia, Settleman, Jeffrey E.
Published in Cancer research (Chicago, Ill.) (15.04.2010)
Published in Cancer research (Chicago, Ill.) (15.04.2010)
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Journal Article
A Man with Back Pain and a Mass in the Lung
SEQUIST, Lecia V, SETTLEMAN, Jeffrey E, ACKMAN, Jeanne B, LAFRATE, A. John
Published in The New England journal of medicine (2008)
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Published in The New England journal of medicine (2008)
Journal Article
Case records of the Massachusetts General Hospital. Case 23-2008. A 26-year-old man with back pain and a mass in the lung
Sequist, Lecia V, Settleman, Jeffrey E, Ackman, Jeanne B, Iafrate, A John
Published in The New England journal of medicine (24.07.2008)
Published in The New England journal of medicine (24.07.2008)
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Conference Proceeding
Method to determine responsiveness of cancer to epidermal growth factor receptor targeting treatments
Meyerson, Matthew, Sellers, William R, Bell, Daphne Winifred, Janne, Pasi Antero, Paez, Juan Guillermo, Johnson, Bruce E, Sordella, Raffaella, Settleman, Jeffrey E, Haber, Daniel A, Lynch, Thomas J
Year of Publication 11.06.2024
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Year of Publication 11.06.2024
Patent
METHOD FOR TREATING GEFITINIB RESISTANT CANCER
Godin-Heymann, Nadia G, Bell, Daphne Winifred, Sordella, Raffaella, Rabindran, Sridhar Krishna, Settleman, Jeffrey E, Haber, Daniel A, Kwak, Eunice L
Year of Publication 20.07.2023
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Year of Publication 20.07.2023
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Biomarkers of response to NAE inhibitors
Blank, Jonathan L, Blakemore, Stephen J, Smith, Peter G, Schu, Matthew C, Mulligan, George J, Benes, Cyril H, Lightcap, Eric S, Settleman, Jeffrey E
Year of Publication 23.03.2021
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Year of Publication 23.03.2021
Patent
METHOD TO DETERMINE RESPONSIVENESS OF CANCER TO EPIDERMAL GROWTH FACTOR RECEPTOR TARGETING TREATMENTS
LYNCH, Thomas J, BELL, Daphne Winifred, JANNE, Pasi Antero, PAEZ, Juan Guillermo, SORDELLA, Raffaella, SELLERS, William R, HABER, Daniel A, JOHNSON, Bruce E, MEYERSON, Matthew, SETTLEMAN, Jeffrey E
Year of Publication 21.01.2021
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Year of Publication 21.01.2021
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