E7050: A dual c‐Met and VEGFR‐2 tyrosine kinase inhibitor promotes tumor regression and prolongs survival in mouse xenograft models
Nakagawa, Takayuki, Tohyama, Osamu, Yamaguchi, Atsumi, Matsushima, Tomohiro, Takahashi, Keiko, Funasaka, Setsuo, Shirotori, Shuji, Asada, Makoto, Obaishi, Hiroshi
Published in Cancer science (01.01.2010)
Published in Cancer science (01.01.2010)
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E7090, a Novel Selective Inhibitor of Fibroblast Growth Factor Receptors, Displays Potent Antitumor Activity and Prolongs Survival in Preclinical Models
Watanabe Miyano, Saori, Yamamoto, Yuji, Kodama, Kotaro, Miyajima, Yukiko, Mikamoto, Masaki, Nakagawa, Takayuki, Kuramochi, Hiroko, Funasaka, Setsuo, Nagao, Satoshi, Sugi, Naoko Hata, Okamoto, Kiyoshi, Minoshima, Yukinori, Nakatani, Yusuke, Karoji, Yuki, Ohashi, Isao, Yamane, Yoshinobu, Okada, Toshimi, Matsushima, Tomohiro, Matsui, Junji, Iwata, Masao, Uenaka, Toshimitsu, Tsuruoka, Akihiko
Published in Molecular cancer therapeutics (01.11.2016)
Published in Molecular cancer therapeutics (01.11.2016)
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Microregional antitumor activity of a small-molecule hypoxia-inducible factor 1 inhibitor
OKAMOTO, KIYOSHI, ITO, DAISUKE, MIYAZAKI, KAZUKI, WATANABE, SAORI, TOHYAMA, OSAMU, YOKOI, AKIRA, OZAWA, YOICHI, ASANO, MAKOTO, KAWAMURA, TAKANORI, YAMANE, YOSHINOBU, NAGAO, SATOSHI, FUNASAKA, SETSUO, KAMATA, JUNICHI, KOTAKE, YOSHIHIKO, AOKI, MIKA, TSUKAHARA, NAOKO, MIZUI, YOSHIHARU, TANAKA, ISAO, SAWADA, KOHEI
Published in International journal of molecular medicine (01.04.2012)
Published in International journal of molecular medicine (01.04.2012)
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Catalytic and Stereoselective Glycosylation with Glucosyl Thioformimidates
Chiba, Hiroyuki, Funasaka, Setsuo, Mukaiyama, Teruaki
Published in Bulletin of the Chemical Society of Japan (01.08.2003)
Published in Bulletin of the Chemical Society of Japan (01.08.2003)
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Eribulin mesilate versus vinorelbine in women with locally recurrent or metastatic breast cancer: A randomised clinical trial
Yuan, Peng, Hu, Xichun, Sun, Tao, Li, Wei, Zhang, Qingyuan, Cui, Shude, Cheng, Ying, Ouyang, Quchang, Wang, Xiaojia, Chen, Zhendong, Hiraiwa, Masahide, Saito, Kenichi, Funasaka, Setsuo, Xu, Binghe
Published in European journal of cancer (1990) (01.05.2019)
Published in European journal of cancer (1990) (01.05.2019)
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Effects of Food, Gastric Acid Reduction, and Strong CYP3A Induction on the Pharmacokinetics of Tasurgratinib, a Novel Selective Fibroblast Growth Factor Receptor Inhibitor
Nomoto, Maiko, Hasunuma, Tomoko, Cai, Cuiyuan, Suzuki, Ippei, Mikubo, Ayano, Funasaka, Setsuo, Otake, Yohei, Nakai, Kenya, Yasuda, Sanae
Published in Journal of clinical pharmacology (01.08.2024)
Published in Journal of clinical pharmacology (01.08.2024)
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Pivotal single-arm, phase 2 trial of tasurgratinib for patients with fibroblast growth factor receptor (FGFR)-2 gene fusion-positive cholangiocarcinoma (CCA)
Furuse, Junji, Jiang, Bo, Kuwahara, Takamichi, Satoh, Taroh, Ma, Xuelei, Yan, Sheng, Zhao, Hai-Tao, Ikeda, Masafumi, Cui, Tongjian, Sasaki, Takashi, Meng, Zhiqiang, Nakai, Yousuke, Ueno, Makoto, Komatsu, Yoshito, Nagano, Hiroaki, Morizane, Chigusa, Funasaka, Setsuo, Ikezawa, Hiroki, Nakada, Takuya, Shen, Lin
Published in Journal of clinical oncology (20.01.2024)
Published in Journal of clinical oncology (20.01.2024)
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Tasurgratinib in patients with cholangiocarcinoma or gastric cancer: Expansion part of the first-in-human phase I study
Morizane, Chigusa, Ueno, Makoto, Ioka, Tatsuya, Tajika, Masahiro, Ikeda, Masafumi, Yamaguchi, Kensei, Hara, Hiroki, Yabusaki, Hiroshi, Miyamoto, Atsushi, Iwasa, Satoru, Muto, Manabu, Takashima, Tsutomu, Minashi, Keiko, Komatsu, Yoshito, Nishina, Tomohiro, Nakajima, Takako Eguchi, Takeno, Atsuchi, Moriwaki, Toshikazu, Furukawa, Masayuki, Sahara, Takatoshi, Ikezawa, Hiroki, Nomoto, Maiko, Takashima, Shuya, Uehara, Taisuke, Funasaka, Setsuo, Yashiro, Masakazu, Furuse, Junji
Published in Cancer science (27.10.2024)
Published in Cancer science (27.10.2024)
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Expansion part of phase I study of E7090 in patients with cholangiocarcinoma harboring FGFR2 gene fusion and with gastric cancer harboring FGFR2 gene amplification or FGFR2 protein high expression
Morizane, Chigusa, Ueno, Makoto, Ioka, Tatsuya, Tajika, Masahiro, Ikeda, Masafumi, Yamaguchi, Kensei, Hara, Hiroki, Yabusaki, Hiroshi, Miyamoto, Atsushi, Iwasa, Satoru, Muto, Manabu, Takashima, Tsutomu, Minashi, Keiko, Komatsu, Yoshito, Nishina, Tomohiro, Nakajima, Takako Eguchi, Sahara, Takatoshi, Funasaka, Setsuo, Yashiro, Masakazu, Furuse, Junji
Published in Journal of clinical oncology (01.02.2020)
Published in Journal of clinical oncology (01.02.2020)
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MO38-3 Clinical update with genomic analyses in expansion part of phase 1 study of selective FGFR inhibitor E7090
Ueno, Makoto, Morizane, Chigusa, Ioka, Tatsuya, Tajika, Masahiro, Ikeda, Masafumi, Yamaguchi, Kensei, Hara, Hiroki, Yabusaki, Hiroshi, Miyamoto, Atsushi, Iwasa, Satoru, Muto, Manabu, Takashima, Tsutomu, Minashi, Keiko, Komatsu, Yoshito, Nishina, Tomohiro, Nakajima, Takako, Sahara, Takatoshi, Uehara, Taisuke, Funasaka, Setsuo, Yashiro, Masakazu, Furuse, Junji
Published in Annals of oncology (01.07.2021)
Published in Annals of oncology (01.07.2021)
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Synthesis and structure–activity relationships of novel, potent, orally active hypoxia-inducible factor-1 inhibitors
Nagao, Satoshi, Yamane, Yoshinobu, Funasaka, Setsuo, Tanaka, Keigo, Miyazaki, Kazuki, Kotake, Yoshihiko, Kamata, Jun-ichi, Watanabe-Miyano, Saori, Toyama, Osamu, Ozawa, Yoichi, Mizui, Yoshiharu, Okamoto, Kiyoshi, Ito, Daisuke
Published in Bioorganic & medicinal chemistry (01.10.2014)
Published in Bioorganic & medicinal chemistry (01.10.2014)
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Abstract 770: E7090: A potent and selective FGFR inhibitor with activity in multiple FGFR-driven cancer models with distinct mechanisms of activation
Miyano, Saori Watanabe, Yamamoto, Yuji, Kodama, Kotaro, Funasaka, Setsuo, Nagao, Satoshi, Sugi, Naoko Hata, Kuramochi, Hiroko, Ishikawa, Katsuyuki, Okamoto, Kiyoshi, Minoshima, Yukinori, Nakagawa, Takayuki, Nakatani, Yusuke, Karoji, Yuki, Ohashi, Isao, Yamane, Yoshinobu, Tanaka, Keigo, Okada, Toshimi, Matsushima, Tomohiro, Matsui, Junji, Iwata, Masao, Tsuruoka, Akihiko, Uenaka, Toshimitsu
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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