Degradation of Janus kinases in CRLF2-rearranged acute lymphoblastic leukemia
Chang, Yunchao, Min, Jaeki, Jarusiewicz, Jamie A., Actis, Marisa, Yu-Chen Bradford, Shanshan, Mayasundari, Anand, Yang, Lei, Chepyala, Divyabharathi, Alcock, Lisa J., Roberts, Kathryn G., Nithianantham, Stanley, Maxwell, Dylan, Rowland, Lauren, Larsen, Randolph, Seth, Aman, Goto, Hiroaki, Imamura, Toshihiko, Akahane, Koshi, Hansen, Baranda S., Pruett-Miller, Shondra M., Paietta, Elisabeth M., Litzow, Mark R., Qu, Chunxu, Yang, Jun J., Fischer, Marcus, Rankovic, Zoran, Mullighan, Charles G.
Published in Blood (09.12.2021)
Published in Blood (09.12.2021)
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Modeling and targeting of erythroleukemia by hematopoietic genome editing
Iacobucci, Ilaria, Qu, Chunxu, Varotto, Elena, Janke, Laura J., Yang, Xu, Seth, Aman, Shelat, Anang, Friske, Jake D., Fukano, Reiji, Yu, Jiyang, Freeman, Burgess B., Kennedy, James A., Sperling, Adam S., Zheng, Rena, Wang, Yingzhe, Jogiraju, Harini, Dickerson, Kirsten M., Payne-Turner, Debbie, Morris, Sarah M., Hollis, Emily S., Ghosn, Nina, Haggard, Georgia E., Lindsley, R. Coleman, Ebert, Benjamin L., Mullighan, Charles G.
Published in Blood (25.03.2021)
Published in Blood (25.03.2021)
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Journal Article
Proteasome inhibition targets the KMT2A transcriptional complex in acute lymphoblastic leukemia
Kamens, Jennifer L., Nance, Stephanie, Koss, Cary, Xu, Beisi, Cotton, Anitria, Lam, Jeannie W., Garfinkle, Elizabeth A. R., Nallagatla, Pratima, Smith, Amelia M. R., Mitchell, Sharnise, Ma, Jing, Currier, Duane, Wright, William C., Kavdia, Kanisha, Pagala, Vishwajeeth R., Kim, Wonil, Wallace, LaShanale M., Cho, Ji-Hoon, Fan, Yiping, Seth, Aman, Twarog, Nathaniel, Choi, John K., Obeng, Esther A., Hatley, Mark E., Metzger, Monika L., Inaba, Hiroto, Jeha, Sima, Rubnitz, Jeffrey E., Peng, Junmin, Chen, Taosheng, Shelat, Anang A., Guy, R. Kiplin, Gruber, Tanja A.
Published in Nature communications (13.02.2023)
Published in Nature communications (13.02.2023)
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Author Correction: Proteasome inhibition targets the KMT2A transcriptional complex in acute lymphoblastic leukemia
Kamens, Jennifer L., Nance, Stephanie, Koss, Cary, Xu, Beisi, Cotton, Anitria, Lam, Jeannie W., Garfinkle, Elizabeth A. R., Nallagatla, Pratima, Smith, Amelia M. R., Mitchell, Sharnise, Ma, Jing, Currier, Duane, Wright, William C., Kavdia, Kanisha, Pagala, Vishwajeeth R., Kim, Wonil, Wallace, LaShanale M., Cho, Ji-Hoon, Fan, Yiping, Seth, Aman, Twarog, Nathaniel, Choi, John K., Obeng, Esther A., Hatley, Mark E., Metzger, Monika L., Inaba, Hiroto, Jeha, Sima, Rubnitz, Jeffrey E., Peng, Junmin, Chen, Taosheng, Shelat, Anang A., Guy, R. Kiplin, Gruber, Tanja A.
Published in Nature communications (09.03.2023)
Published in Nature communications (09.03.2023)
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Journal Article
Topoisomerase assays
Nitiss, John L, Soans, Eroica, Rogojina, Anna, Seth, Aman, Mishina, Margarita
Published in Current protocols in pharmacology (01.06.2012)
Published in Current protocols in pharmacology (01.06.2012)
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CD62L and TCR αβ Depletion of Donors in a Double Haploidentical BMT Model Leads to Improved Donor Engraftment
Seth, Aman, MS, Sinha, Chandrima, PhD, Kahali, Bhaskar, PhD, Leung, Wing H., MD, PhD, Cunningham, Lea, MD
Published in Biology of blood and marrow transplantation (01.03.2016)
Published in Biology of blood and marrow transplantation (01.03.2016)
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Journal Article
Modulation of NKG2D Ligands Expression in Acute Myeloid Leukemia
Sinha, Chandrima, PhD, Ju, Bensheng, PhD, Ong, Su Sien, PhD, Goktug, Asli, MS, Lin, Wenwei, PhD, Seth, Aman, MS, Kahali, Bhaskar, PhD, Chen, Taosheng, PhD, Leung, Wing H., MD, PhD, Cunningham, Lea, MD
Published in Biology of blood and marrow transplantation (01.03.2016)
Published in Biology of blood and marrow transplantation (01.03.2016)
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Journal Article
ETV6-NTRK3 induces aggressive acute lymphoblastic leukemia highly sensitive to selective TRK inhibition
Roberts, Kathryn G., Janke, Laura J., Zhao, Yaqi, Seth, Aman, Ma, Jing, Finkelstein, David, Smith, Steve, Ebata, Kevin, Tuch, Brian B., Hunger, Stephen P., Mullighan, Charles G.
Published in Blood (23.08.2018)
Published in Blood (23.08.2018)
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Non-Myeloablative TLI/ATG + Alkylator Conditioning Augments Bidirectional Immune Tolerance Via Regulatory MDSC in a Robust Murine Model of MHC-Mismatched BMT for Beta-Thalassemia
Seth, Aman, MS, Shuyu, E., MD PhD, Abdelsamed, Hossam, PhD, Vogel, Peter, DVM, PhD, Pillai, Asha, MD
Published in Biology of blood and marrow transplantation (01.02.2015)
Published in Biology of blood and marrow transplantation (01.02.2015)
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Journal Article
Loss of PTEN in Pediatric AML Confers Sensitivity to PARP Inhibition
Kamens, Jennifer Lauren, Cotton, Anitria, Lam, Jeannie W, Dang, Jinjun, Seth, Aman, Hansen, Baranda S, Pruett-Miller, Shondra M., Shelat, Anang, Gruber, Tanja Andrea
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
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Journal Article
NUP98-KDM5A Fusion Induces Hematopoietic Cell Proliferation and Alters Myelo-Erythropoietic Differentiation
Miller, Jonathan, Hiltenbrand, Ryan, Lamprecht, Tamara, Seth, Aman, Abdelhamed, Sherif, Iacobucci, Ilaria, Mullighan, Charles G., Klco, Jeffery M.
Published in Blood (13.11.2019)
Published in Blood (13.11.2019)
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Journal Article
Bidirectional immune tolerance in nonmyeloablative MHC-mismatched BMT for murine β-thalassemia
E, Shuyu, Seth, Aman, Vogel, Peter, Sommers, Matt, Ong, Taren, Pillai, Asha B.
Published in Blood (01.06.2017)
Published in Blood (01.06.2017)
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Journal Article
An Evaluation of the Cytotoxic Effect of the Natural Product Aaptamine Against t(4;11) Leukemias
Sinha, Chandrima, Bowling, John, Seth, Aman, Ju, Bensheng, Kahali, Bhaskar, Hamann, Mark, Cunningham, Lea C.
Published in Blood (02.12.2016)
Published in Blood (02.12.2016)
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Journal Article
Poster: ALL-090 Highly Effective Combination of FLT3 and BCL2 Inhibitors in a Preclinical Model of Lineage Ambiguous Leukemia
Montefiori, Lindsey, Iacobucci, Ilaria, Budhraja, Amit, Moore, Jamila, Baskin, Rebekah, DeVries, Rebekah, Backhaus, Emily, Johnson, Melissa, Akers, Walter, Chepyala, Divyabharathi, Mehr, Cyrus, Seth, Aman, Mead, Paul, Opferman, Joseph, Mullighan, Charles
Published in Clinical lymphoma, myeloma and leukemia (01.10.2022)
Published in Clinical lymphoma, myeloma and leukemia (01.10.2022)
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Journal Article
ALL-090 Highly Effective Combination of FLT3 and BCL2 Inhibitors in a Preclinical Model of Lineage Ambiguous Leukemia
Montefiori, Lindsey, lacobucci, Ilaria, Budhraja, Amit, Moore, Jamila, Baskin, Rebekah, DeVries, Rebekah, Backhaus, Emily, Johnson, Melissa, Akers, Walter, Chepyala, Divyabharathi, Mehr, Cyrus, Seth, Aman, Mead, Paul, Opferman, Joseph, Mullighan, Charles
Published in Clinical lymphoma, myeloma and leukemia (01.10.2022)
Published in Clinical lymphoma, myeloma and leukemia (01.10.2022)
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Journal Article
Recipient myeloid-derived immunomodulatory cells induce PD-1 ligand-dependent donor CD4+Foxp3+ regulatory T cell proliferation and donor-recipient immune tolerance after murine nonmyeloablative bone marrow transplantation
van der Merwe, Marie, Abdelsamed, Hossam A, Seth, Aman, Ong, Taren, Vogel, Peter, Pillai, Asha B
Published in The Journal of immunology (1950) (01.12.2013)
Published in The Journal of immunology (1950) (01.12.2013)
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Journal Article
Multiplex CRISPR/Cas9-Based Genome Editing of Mouse Hematopoietic Stem Cells Recapitulates Acute Erythroid Leukemia and Identifies Therapeutic Targets
Iacobucci, Ilaria, Varotto, Elena, Qu, Chunxu, Janke, Laura, Seth, Aman, Shelat, Anang, Freeman, Burgess, Kennedy, James, Sperling, Adam S, Lindsley, R. Coleman, Dickerson, Kirsten, Payne-Turner, Debbie, Morris, Sarah M, Ghosn, Nina, Ebert, Benjamin L., Mullighan, Charles G.
Published in Blood (29.11.2018)
Published in Blood (29.11.2018)
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Journal Article
Abstract IA12: Modeling and targeting CREBBP mutations in relapsed acute lymphoblastic leukemia
Chang, Yunchao, Woessner, David W., Lin, Wenwei, Chen, Taosheng, Xu, Beisi, Fan, Yiping, Tan, Haiyan, Peng, Junmin, Kasper, Lawryn, Churchman, Michelle L., Gerhard, Daniela S., Loh, Mignon L., Hunger, Stephen P., Seth, Aman, Gascoigne, Karen, Mullighan, Charles G.
Published in Cancer research (Chicago, Ill.) (01.10.2018)
Published in Cancer research (Chicago, Ill.) (01.10.2018)
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CREBBP Histone Acetyltransferase Domain Mutations Result in Dexamethasone Resistance in B-Progenitor Acute Lymphoblastic Leukemia
Chang, Yunchao, Woessner, David W., Lin, Wenwei, Chen, Taosheng, Xu, Beisi, Fan, Yiping, Tan, Haiyan, Peng, Junmin, Kasper, Lawryn, Churchman, Michelle L., Loh, Mignon L., Hunger, Stephen P., Seth, Aman, Gascoigne, Karen, Brindle, Paul K, Mullighan, Charles G.
Published in Blood (08.12.2017)
Published in Blood (08.12.2017)
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